5BPGA

Crystal structure of the water-soluble frac purified starting from the trans-membrane pore
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
177
structure length
177
Chain Sequence
DVAGAVIDGAGLGFDVLKTVLEALGNVKRKIAVGIDNESGKTWTAMNTYFRSGTSDIVLPHKVAHGKALLYNGQKNRGPVATGVVGVIAYSMSDGNTLAVLFSVPYDYNWYSNWWNVRVYKGQKRADQRMYEELYYHRSPFRGDNGWHSRGLGYGLKSRGFMNSSGHAILEIHVTKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bidirectional Transformation of a Metamorphic Protein between the Water-Soluble and Transmembrane Native States
pubmed doi rcsb
molecule tags Toxin
source organism Actinia fragacea
molecule keywords Fragaceatoxin C
total genus 49
structure length 177
sequence length 177
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2015-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06369 Anemone_cytotox Sea anemone cytotoxic protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.270.20 Mainly Beta Sandwich Mutm (Fpg) Protein; Chain: A, domain 2 Cytolysin/lectin 5bpgA00
3QDSA 4TSLA 4Z2QA 1Y2XA 2L38A 1Y2UA 3ZWGA 1O72A 4YLDA 3QDYA 3QDVA 1Y2VA 3QDWA 2OFCA 3QDXA 1IAZA 1Y2TA 4TSOA 1Y2WA 3VWIA 4TSPA 4WDCA 5BPGA 2L2BA 3QDTA 2KS4A 3W9PA 1KD6A 1GWYA 1X99A 3QDUA 4TSQA 1O71A 4TSYA 3LIMA 4TSNA 4Z2FA 2OFDA 4Z2SA 3ZWJA 2OFEA 1TZQA 1XI0A
chains in the Genus database with same CATH superfamily
3QDSA 4TSLA 4Z2QA 1Y2XA 2L38A 4JOXA 1Y2UA 4WX5A 3ZWGA 1O72A 4YLDA 3QDYA 3QDVA 1Y2VA 3QDWA 2OFCA 4HPQB 3A57A 1IAZA 1Y2TA 3QDXA 4TSOA 1Y2WA 3VWIA 4TSPA 4WDCA 3ZWJA 5BPGA 5JHFB 4P1WB 2L2BA 3QDTA 2KS4A 3W9PA 1KD6A 1GWYA 1X99A 3QDUA 4TSQA 1O71A 4OEBA 4TSYA 3LIMA 4TSNA 4Z2FA 2OFDA 4Z2SA 4WX3A 2OFEA 1TZQA 1XI0A
chains in the Genus database with same CATH topology
3QDSA 4TSLA 4Z2QA 1Y2XA 2L38A 1Y2UA 3ZWGA 1O72A 4YLDA 3QDYA 3QDVA 1Y2VA 3QDWA 2OFCA 3QDXA 1IAZA 1Y2TA 4TSOA 1Y2WA 3VWIA 4TSPA 4WDCA 5BPGA 2L2BA 3QDTA 2KS4A 3W9PA 1KD6A 1GWYA 1X99A 3QDUA 4TSQA 1O71A 4TSYA 3LIMA 4TSNA 4Z2FA 2OFDA 4Z2SA 3ZWJA 2OFEA 1TZQA 1XI0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QDS A;  4TSL A;  4Z2Q A;  1Y2X A;  2L38 A;  1Y2U A;  3ZWG A;  1O72 A;  4YLD A;  3QDY A;  3QDV A;  1Y2V A;  3QDW A;  2OFC A;  3QDX A;  1IAZ A;  1Y2T A;  4TSO A;  1Y2W A;  3VWI A;  4TSP A;  4WDC A;  5BPG A;  2L2B A;  3QDT A;  2KS4 A;  3W9P A;  1KD6 A;  1GWY A;  1X99 A;  3QDU A;  4TSQ A;  1O71 A;  4TSY A;  3LIM A;  4TSN A;  4Z2F A;  2OFD A;  4Z2S A;  3ZWJ A;  2OFE A;  1TZQ A;  1XI0 A; 
#chains in the Genus database with same CATH topology
 3QDS A;  4TSL A;  4Z2Q A;  1Y2X A;  2L38 A;  4JOX A;  1Y2U A;  4WX5 A;  3ZWG A;  1O72 A;  4YLD A;  3QDY A;  3QDV A;  1Y2V A;  3QDW A;  2OFC A;  4HPQ B;  3A57 A;  1IAZ A;  1Y2T A;  3QDX A;  4TSO A;  1Y2W A;  3VWI A;  4TSP A;  4WDC A;  3ZWJ A;  5BPG A;  5JHF B;  4P1W B;  2L2B A;  3QDT A;  2KS4 A;  3W9P A;  1KD6 A;  1GWY A;  1X99 A;  3QDU A;  4TSQ A;  1O71 A;  4OEB A;  4TSY A;  3LIM A;  4TSN A;  4Z2F A;  2OFD A;  4Z2S A;  4WX3 A;  2OFE A;  1TZQ A;  1XI0 A; 
#chains in the Genus database with same CATH homology
 3QDS A;  4TSL A;  4Z2Q A;  1Y2X A;  2L38 A;  1Y2U A;  3ZWG A;  1O72 A;  4YLD A;  3QDY A;  3QDV A;  1Y2V A;  3QDW A;  2OFC A;  3QDX A;  1IAZ A;  1Y2T A;  4TSO A;  1Y2W A;  3VWI A;  4TSP A;  4WDC A;  5BPG A;  2L2B A;  3QDT A;  2KS4 A;  3W9P A;  1KD6 A;  1GWY A;  1X99 A;  3QDU A;  4TSQ A;  1O71 A;  4TSY A;  3LIM A;  4TSN A;  4Z2F A;  2OFD A;  4Z2S A;  3ZWJ A;  2OFE A;  1TZQ A;  1XI0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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