5CLNA

Crystal structure of a 4-oxalocrotonate tautomerase mutant at 2.7 angstrom
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
57
structure length
57
Chain Sequence
PIAQIHILEGRSDEQKETLIREVSEAISRSLDAPLTSVRVIITEYAKGHAGIGGELA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases.
pubmed doi rcsb
molecule tags Isomerase
source organism Pseudomonas putida
molecule keywords 2-hydroxymuconate tautomerase
total genus 15
structure length 57
sequence length 57
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L
ec nomenclature ec 5.3.2.6: 2-hydroxymuconate tautomerase.
pdb deposition date 2015-07-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.429.10 Alpha Beta 2-Layer Sandwich Macrophage Migration Inhibitory Factor Macrophage Migration Inhibitory Factor 5clnA00
4OTCA 5CLOA 5BSCA 4FAZA 4K9GA 4OYQA 4P7SA 1OTGA 5HVSA 2X4KA 1FIMA 4X19A 3L5PA 1MWWA 3SMBA 2OOWA 3MB2A 1CGQA 4TRFA 4U5PA 1S0YB 4PKKA 3WNRA 2OPAA 4OTAA 2WKBA 4WR8A 2AAGA 3N4GA 3SMCA 3WNTA 4X1CC 4P0HA 3RF4A 3EJ9A 3FWUA 1GD0A 1GYYA 4OTBA 5J7PA 3MF7A 2FM7A 4WRBA 4EUIA 3FWTA 3JSFA 5HVVA 3EJ3B 5BS9A 3KERA 4P01A 1GCZA 3EJ7A 3N4DA 3M21A 1MIFA 5BSJA 4U5RA 4X1CA 1UIZA 3GADA 4JCUA 2GDGA 4NWQB 3RY0A 4P7MA 3JSGA 3N4HA 2OOZA 5CLNA 4GRPA 3U18A 1LJTA 4XX7A 3DJHA 3ABFA 3MB2B 3B64A 2FLZA 3GACA 5BSIA 3KANA 4Q3FA 2AAJA 5EIZA 4DH4A 2WKFA 3E6QA 4LKBA 4GRNA 4GROA 4M1AA 4PKZA 1MFFA 3EJ9B 3IJJA 1GYXA 3CE4A 3MJZA 3WNSA 2ORMA 2XCZA 3RF5A 4F2KA 4GRQA 1OTFA 2OOHA 3JTUA 3T5SA 4OSFA 4TRUA 1GYJA 3L5VA 3L5UA 4ETGA 4Z1TA 3C6VA 5HVTA 3MLCA 4FDXA 5B4OA 3L5SA 3L5RA 3M20A 2OP8A 4GRUA 3MF8A 1DPTA 1S0YA 4LHOA 4EVGA 3L5TA 4JJ9A 2OS5A 1GIFA 3DJIA 4XX8A 1P1GA 1BJPA 4PLUA 3HOFA 4GUMA 4Z1UA 3IJGA 4LHPA 1CA7A 4GRRA 1MFIA 2AALA 2WKFB 1U9DA 4NWPE 3EJ3A 4Z15A 2FLTA 3B9SA 3EJ7B 1HFOA 5J7QA
chains in the Genus database with same CATH superfamily
4OTCA 5CLOA 5BSCA 4FAZA 4K9GA 4OYQA 4P7SA 1OTGA 5HVSA 2X4KA 1FIMA 4X19A 3L5PA 1MWWA 3SMBA 2OOWA 3MB2A 1CGQA 4TRFA 4U5PA 1S0YB 4PKKA 3WNRA 2OPAA 4OTAA 2WKBA 4WR8A 2AAGA 3N4GA 3SMCA 3WNTA 4X1CC 4P0HA 3RF4A 3EJ9A 3FWUA 1GD0A 1GYYA 4OTBA 5J7PA 3MF7A 2FM7A 4WRBA 4EUIA 3FWTA 3JSFA 5HVVA 3EJ3B 5BS9A 3KERA 4P01A 1GCZA 3EJ7A 3N4DA 3M21A 1MIFA 5BSJA 4U5RA 4X1CA 1UIZA 3GADA 4JCUA 2GDGA 4NWQB 3RY0A 4P7MA 3JSGA 3N4HA 2OOZA 5CLNA 4GRPA 3U18A 1LJTA 4XX7A 3DJHA 3ABFA 3MB2B 3B64A 2FLZA 3GACA 5BSIA 3KANA 4Q3FA 2AAJA 5EIZA 4DH4A 2WKFA 3E6QA 4LKBA 4GRNA 4GROA 4M1AA 4PKZA 1MFFA 3EJ9B 3IJJA 1GYXA 3CE4A 3MJZA 3WNSA 2ORMA 2XCZA 3RF5A 4F2KA 4GRQA 1OTFA 2OOHA 3JTUA 3T5SA 4OSFA 4TRUA 1GYJA 3L5VA 3L5UA 4ETGA 4Z1TA 3C6VA 5HVTA 3MLCA 4FDXA 5B4OA 3L5SA 3L5RA 3M20A 2OP8A 4GRUA 3MF8A 1DPTA 1S0YA 4LHOA 4EVGA 3L5TA 4JJ9A 2OS5A 1GIFA 3DJIA 4XX8A 1P1GA 1BJPA 4PLUA 3HOFA 4GUMA 4Z1UA 3IJGA 4LHPA 1CA7A 4GRRA 1MFIA 2AALA 2WKFB 1U9DA 4NWPE 3EJ3A 4Z15A 2FLTA 3B9SA 3EJ7B 1HFOA 5J7QA
chains in the Genus database with same CATH topology
4OTCA 5CLOA 5BSCA 4FAZA 4K9GA 4OYQA 4P7SA 1OTGA 5HVSA 2X4KA 1FIMA 4X19A 3L5PA 1MWWA 3SMBA 2OOWA 3MB2A 1CGQA 4TRFA 4U5PA 1S0YB 4PKKA 3WNRA 2OPAA 4OTAA 2WKBA 4WR8A 2AAGA 3N4GA 3SMCA 3WNTA 4X1CC 4P0HA 3RF4A 3EJ9A 3FWUA 1GD0A 1GYYA 4OTBA 5J7PA 3MF7A 2FM7A 4WRBA 4EUIA 3FWTA 3JSFA 5HVVA 3EJ3B 5BS9A 3KERA 4P01A 1GCZA 3EJ7A 3N4DA 3M21A 1MIFA 5BSJA 4U5RA 4X1CA 1UIZA 3GADA 4JCUA 2GDGA 4NWQB 3RY0A 4P7MA 3JSGA 3N4HA 2OOZA 5CLNA 4GRPA 3U18A 1LJTA 4XX7A 3DJHA 3ABFA 3MB2B 3B64A 2FLZA 3GACA 5BSIA 3KANA 4Q3FA 2AAJA 5EIZA 4DH4A 2WKFA 3E6QA 4LKBA 4GRNA 4GROA 4M1AA 4PKZA 1MFFA 3EJ9B 3IJJA 1GYXA 3CE4A 3MJZA 3WNSA 2ORMA 2XCZA 3RF5A 4F2KA 4GRQA 1OTFA 2OOHA 3JTUA 3T5SA 4OSFA 4TRUA 1GYJA 3L5VA 3L5UA 4ETGA 4Z1TA 3C6VA 5HVTA 3MLCA 4FDXA 5B4OA 3L5SA 3L5RA 3M20A 2OP8A 4GRUA 3MF8A 1DPTA 1S0YA 4LHOA 4EVGA 3L5TA 4JJ9A 2OS5A 1GIFA 3DJIA 4XX8A 1P1GA 1BJPA 4PLUA 3HOFA 4GUMA 4Z1UA 3IJGA 4LHPA 1CA7A 4GRRA 1MFIA 2AALA 2WKFB 1U9DA 4NWPE 3EJ3A 4Z15A 2FLTA 3B9SA 3EJ7B 1HFOA 5J7QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OTC A;  5CLO A;  5BSC A;  4FAZ A;  4K9G A;  4OYQ A;  4P7S A;  1OTG A;  5HVS A;  2X4K A;  1FIM A;  4X19 A;  3L5P A;  1MWW A;  3SMB A;  2OOW A;  3MB2 A;  1CGQ A;  4TRF A;  4U5P A;  1S0Y B;  4PKK A;  3WNR A;  2OPA A;  4OTA A;  2WKB A;  4WR8 A;  2AAG A;  3N4G A;  3SMC A;  3WNT A;  4X1C C;  4P0H A;  3RF4 A;  3EJ9 A;  3FWU A;  1GD0 A;  1GYY A;  4OTB A;  5J7P A;  3MF7 A;  2FM7 A;  4WRB A;  4EUI A;  3FWT A;  3JSF A;  5HVV A;  3EJ3 B;  5BS9 A;  3KER A;  4P01 A;  1GCZ A;  3EJ7 A;  3N4D A;  3M21 A;  1MIF A;  5BSJ A;  4U5R A;  4X1C A;  1UIZ A;  3GAD A;  4JCU A;  2GDG A;  4NWQ B;  3RY0 A;  4P7M A;  3JSG A;  3N4H A;  2OOZ A;  5CLN A;  4GRP A;  3U18 A;  1LJT A;  4XX7 A;  3DJH A;  3ABF A;  3MB2 B;  3B64 A;  2FLZ A;  3GAC A;  5BSI A;  3KAN A;  4Q3F A;  2AAJ A;  5EIZ A;  4DH4 A;  2WKF A;  3E6Q A;  4LKB A;  4GRN A;  4GRO A;  4M1A A;  4PKZ A;  1MFF A;  3EJ9 B;  3IJJ A;  1GYX A;  3CE4 A;  3MJZ A;  3WNS A;  2ORM A;  2XCZ A;  3RF5 A;  4F2K A;  4GRQ A;  1OTF A;  2OOH A;  3JTU A;  3T5S A;  4OSF A;  4TRU A;  1GYJ A;  3L5V A;  3L5U A;  4ETG A;  4Z1T A;  3C6V A;  5HVT A;  3MLC A;  4FDX A;  5B4O A;  3L5S A;  3L5R A;  3M20 A;  2OP8 A;  4GRU A;  3MF8 A;  1DPT A;  1S0Y A;  4LHO A;  4EVG A;  3L5T A;  4JJ9 A;  2OS5 A;  1GIF A;  3DJI A;  4XX8 A;  1P1G A;  1BJP A;  4PLU A;  3HOF A;  4GUM A;  4Z1U A;  3IJG A;  4LHP A;  1CA7 A;  4GRR A;  1MFI A;  2AAL A;  2WKF B;  1U9D A;  4NWP E;  3EJ3 A;  4Z15 A;  2FLT A;  3B9S A;  3EJ7 B;  1HFO A;  5J7Q A; 
#chains in the Genus database with same CATH topology
 4OTC A;  5CLO A;  5BSC A;  4FAZ A;  4K9G A;  4OYQ A;  4P7S A;  1OTG A;  5HVS A;  2X4K A;  1FIM A;  4X19 A;  3L5P A;  1MWW A;  3SMB A;  2OOW A;  3MB2 A;  1CGQ A;  4TRF A;  4U5P A;  1S0Y B;  4PKK A;  3WNR A;  2OPA A;  4OTA A;  2WKB A;  4WR8 A;  2AAG A;  3N4G A;  3SMC A;  3WNT A;  4X1C C;  4P0H A;  3RF4 A;  3EJ9 A;  3FWU A;  1GD0 A;  1GYY A;  4OTB A;  5J7P A;  3MF7 A;  2FM7 A;  4WRB A;  4EUI A;  3FWT A;  3JSF A;  5HVV A;  3EJ3 B;  5BS9 A;  3KER A;  4P01 A;  1GCZ A;  3EJ7 A;  3N4D A;  3M21 A;  1MIF A;  5BSJ A;  4U5R A;  4X1C A;  1UIZ A;  3GAD A;  4JCU A;  2GDG A;  4NWQ B;  3RY0 A;  4P7M A;  3JSG A;  3N4H A;  2OOZ A;  5CLN A;  4GRP A;  3U18 A;  1LJT A;  4XX7 A;  3DJH A;  3ABF A;  3MB2 B;  3B64 A;  2FLZ A;  3GAC A;  5BSI A;  3KAN A;  4Q3F A;  2AAJ A;  5EIZ A;  4DH4 A;  2WKF A;  3E6Q A;  4LKB A;  4GRN A;  4GRO A;  4M1A A;  4PKZ A;  1MFF A;  3EJ9 B;  3IJJ A;  1GYX A;  3CE4 A;  3MJZ A;  3WNS A;  2ORM A;  2XCZ A;  3RF5 A;  4F2K A;  4GRQ A;  1OTF A;  2OOH A;  3JTU A;  3T5S A;  4OSF A;  4TRU A;  1GYJ A;  3L5V A;  3L5U A;  4ETG A;  4Z1T A;  3C6V A;  5HVT A;  3MLC A;  4FDX A;  5B4O A;  3L5S A;  3L5R A;  3M20 A;  2OP8 A;  4GRU A;  3MF8 A;  1DPT A;  1S0Y A;  4LHO A;  4EVG A;  3L5T A;  4JJ9 A;  2OS5 A;  1GIF A;  3DJI A;  4XX8 A;  1P1G A;  1BJP A;  4PLU A;  3HOF A;  4GUM A;  4Z1U A;  3IJG A;  4LHP A;  1CA7 A;  4GRR A;  1MFI A;  2AAL A;  2WKF B;  1U9D A;  4NWP E;  3EJ3 A;  4Z15 A;  2FLT A;  3B9S A;  3EJ7 B;  1HFO A;  5J7Q A; 
#chains in the Genus database with same CATH homology
 4OTC A;  5CLO A;  5BSC A;  4FAZ A;  4K9G A;  4OYQ A;  4P7S A;  1OTG A;  5HVS A;  2X4K A;  1FIM A;  4X19 A;  3L5P A;  1MWW A;  3SMB A;  2OOW A;  3MB2 A;  1CGQ A;  4TRF A;  4U5P A;  1S0Y B;  4PKK A;  3WNR A;  2OPA A;  4OTA A;  2WKB A;  4WR8 A;  2AAG A;  3N4G A;  3SMC A;  3WNT A;  4X1C C;  4P0H A;  3RF4 A;  3EJ9 A;  3FWU A;  1GD0 A;  1GYY A;  4OTB A;  5J7P A;  3MF7 A;  2FM7 A;  4WRB A;  4EUI A;  3FWT A;  3JSF A;  5HVV A;  3EJ3 B;  5BS9 A;  3KER A;  4P01 A;  1GCZ A;  3EJ7 A;  3N4D A;  3M21 A;  1MIF A;  5BSJ A;  4U5R A;  4X1C A;  1UIZ A;  3GAD A;  4JCU A;  2GDG A;  4NWQ B;  3RY0 A;  4P7M A;  3JSG A;  3N4H A;  2OOZ A;  5CLN A;  4GRP A;  3U18 A;  1LJT A;  4XX7 A;  3DJH A;  3ABF A;  3MB2 B;  3B64 A;  2FLZ A;  3GAC A;  5BSI A;  3KAN A;  4Q3F A;  2AAJ A;  5EIZ A;  4DH4 A;  2WKF A;  3E6Q A;  4LKB A;  4GRN A;  4GRO A;  4M1A A;  4PKZ A;  1MFF A;  3EJ9 B;  3IJJ A;  1GYX A;  3CE4 A;  3MJZ A;  3WNS A;  2ORM A;  2XCZ A;  3RF5 A;  4F2K A;  4GRQ A;  1OTF A;  2OOH A;  3JTU A;  3T5S A;  4OSF A;  4TRU A;  1GYJ A;  3L5V A;  3L5U A;  4ETG A;  4Z1T A;  3C6V A;  5HVT A;  3MLC A;  4FDX A;  5B4O A;  3L5S A;  3L5R A;  3M20 A;  2OP8 A;  4GRU A;  3MF8 A;  1DPT A;  1S0Y A;  4LHO A;  4EVG A;  3L5T A;  4JJ9 A;  2OS5 A;  1GIF A;  3DJI A;  4XX8 A;  1P1G A;  1BJP A;  4PLU A;  3HOF A;  4GUM A;  4Z1U A;  3IJG A;  4LHP A;  1CA7 A;  4GRR A;  1MFI A;  2AAL A;  2WKF B;  1U9D A;  4NWP E;  3EJ3 A;  4Z15 A;  2FLT A;  3B9S A;  3EJ7 B;  1HFO A;  5J7Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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