5CXYA

Structure of a glycosyltransferase in complex with inhibitor
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
292
structure length
292
Chain Sequence
KWKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title To be published.
rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransfer
total genus 95
structure length 292
sequence length 292
chains with identical sequence B
ec nomenclature ec 2.4.99.-:
pdb deposition date 2015-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00777 Glyco_transf_29 Glycosyltransferase family 29 (sialyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1480.20 Alpha Beta Alpha-Beta Complex sialyltransferase cstii, chain A sialyltransferase cstii, chain A 5cxyA00
2WNBA 5BO6A 5BO8A 4JS2A 2WNFA 5CXYA 5BO9A 5BO7A 4JS1A 4MPSA 2WMLA
chains in the Genus database with same CATH superfamily
2X63A 5BO9A 5BO7A 2X62A 1RO8A 2X61A 2P56A 2WNBA 1RO7A 4JS1A 4MPSA 2DRJA 2WNFA 2WMLA 5BO8A 4JS2A 5CXYA 2WQQA 2P2VA 5BO6A
chains in the Genus database with same CATH topology
2WNBA 5BO6A 5BO8A 4JS2A 2WNFA 5CXYA 5BO9A 5BO7A 4JS1A 4MPSA 2WMLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WNB A;  5BO6 A;  5BO8 A;  4JS2 A;  2WNF A;  5CXY A;  5BO9 A;  5BO7 A;  4JS1 A;  4MPS A;  2WML A; 
#chains in the Genus database with same CATH topology
 2X63 A;  5BO9 A;  5BO7 A;  2X62 A;  1RO8 A;  2X61 A;  2P56 A;  2WNB A;  1RO7 A;  4JS1 A;  4MPS A;  2DRJ A;  2WNF A;  2WML A;  5BO8 A;  4JS2 A;  5CXY A;  2WQQ A;  2P2V A;  5BO6 A; 
#chains in the Genus database with same CATH homology
 2WNB A;  5BO6 A;  5BO8 A;  4JS2 A;  2WNF A;  5CXY A;  5BO9 A;  5BO7 A;  4JS1 A;  4MPS A;  2WML A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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