5BO7A

Structure of human sialyltransferase st8siaiii in complex with ctp
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
292
structure length
290
Chain Sequence
KWKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKESHQLPAEFQLLYRMHGEGLTKLTLSHCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransfer
total genus 94
structure length 290
sequence length 292
chains with identical sequence B
ec nomenclature ec 2.4.99.-:
pdb deposition date 2015-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00777 Glyco_transf_29 Glycosyltransferase family 29 (sialyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1480.20 Alpha Beta Alpha-Beta Complex sialyltransferase cstii, chain A sialyltransferase cstii, chain A 5bo7A00
4JS2A 5BO6A 4JS1A 2WMLA 5BO7A 5BO8A 5BO9A 5CXYA 2WNBA 4MPSA 2WNFA
chains in the Genus database with same CATH superfamily
2X63A 5BO8A 1RO8A 2WNFA 2X62A 4JS1A 5CXYA 2WNBA 1RO7A 2X61A 5BO7A 5BO9A 2DRJA 2P2VA 4JS2A 5BO6A 2P56A 2WMLA 2WQQA 4MPSA
chains in the Genus database with same CATH topology
4JS2A 5BO6A 4JS1A 2WMLA 5BO7A 5BO8A 5BO9A 5CXYA 2WNBA 4MPSA 2WNFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JS2 A;  5BO6 A;  4JS1 A;  2WML A;  5BO7 A;  5BO8 A;  5BO9 A;  5CXY A;  2WNB A;  4MPS A;  2WNF A; 
#chains in the Genus database with same CATH topology
 2X63 A;  5BO8 A;  1RO8 A;  2WNF A;  2X62 A;  4JS1 A;  5CXY A;  2WNB A;  1RO7 A;  2X61 A;  5BO7 A;  5BO9 A;  2DRJ A;  2P2V A;  4JS2 A;  5BO6 A;  2P56 A;  2WML A;  2WQQ A;  4MPS A; 
#chains in the Genus database with same CATH homology
 4JS2 A;  5BO6 A;  4JS1 A;  2WML A;  5BO7 A;  5BO8 A;  5BO9 A;  5CXY A;  2WNB A;  4MPS A;  2WNF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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