6ACNA

Structure of activated aconitase. formation of the (4fe-4s) cluster in the crystal
Total Genus 292
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
292
sequence length
754
structure length
754
Chain Sequence
ERAKVAMSHFEPHEYIRYDLLEKNIDIVRKRLNRPLTLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQLGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRADIANLADEFKDHLVPDPGCHYDQVIEINLSELKPHINGPFTPDLAHPVAEVGSVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQVLRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRAEFDPGQDTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENRKANSVRNAVTQEFGPVPDTARYYKQHGIRWVVIGDENYGEGSSREHSALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLKDFAPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of activated aconitase: formation of the [4Fe-4S] cluster in the crystal.
pubmed doi rcsb
molecule tags Lyase(carbon-oxygen)
source organism Sus scrofa
molecule keywords ACONITASE
total genus 292
structure length 754
sequence length 754
ec nomenclature ec 4.2.1.3: Aconitate hydratase.
pdb deposition date 1990-01-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00330 Aconitase Aconitase family (aconitate hydratase)
A PF00694 Aconitase_C Aconitase C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.19.10 Alpha Beta Alpha-Beta Barrel Aconitase; domain 4 Aconitase, domain 4 6acnA04
3.30.499.10 Alpha Beta 2-Layer Sandwich Aconitase; domain 3 Aconitase, domain 3 6acnA01
3.30.499.10 Alpha Beta 2-Layer Sandwich Aconitase; domain 3 Aconitase, domain 3 6acnA03
3.40.1060.10 Alpha Beta 3-Layer(aba) Sandwich Aconitase; Domain 2 Aconitase, Domain 2 6acnA02
1V7LA 2PKPA 3SNPA 1C96A 3H5HA 1B0JA 1NITA 1AMIA 4KP1A 5ACNA 1B0KA 2HCUA 1L5JA 1C97A 1FGHA 6ACNA 2B3XA 7ACNA 1ACOA 1NISA 3SN2A 4KP2A 1B0MA 2B3YA 1AMJA 3Q3WA 4NQYA 3VBAA 8ACNA 3H5EA 3H5JA
chains in the Genus database with same CATH superfamily
1V7LA 2PKPA 3SNPA 1C96A 3H5HA 1B0JA 1NITA 1AMIA 4KP1A 5ACNA 1B0KA 2HCUA 1L5JA 1C97A 1FGHA 6ACNA 2B3XA 7ACNA 1ACOA 1NISA 3SN2A 4KP2A 1B0MA 2B3YA 1AMJA 3Q3WA 4NQYA 3VBAA 8ACNA 3H5EA 3H5JA
chains in the Genus database with same CATH topology
1V7LA 2PKPA 3SNPA 1C96A 3H5HA 1B0JA 1NITA 1AMIA 4KP1A 5ACNA 1B0KA 2HCUA 1L5JA 1C97A 1FGHA 6ACNA 2B3XA 7ACNA 1ACOA 1NISA 3SN2A 4KP2A 1B0MA 2B3YA 1AMJA 3Q3WA 4NQYA 3VBAA 8ACNA 3H5EA 3H5JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1V7L A;  2PKP A;  3SNP A;  1C96 A;  3H5H A;  1B0J A;  1NIT A;  1AMI A;  4KP1 A;  5ACN A;  1B0K A;  2HCU A;  1L5J A;  1C97 A;  1FGH A;  6ACN A;  2B3X A;  7ACN A;  1ACO A;  1NIS A;  3SN2 A;  4KP2 A;  1B0M A;  2B3Y A;  1AMJ A;  3Q3W A;  4NQY A;  3VBA A;  8ACN A;  3H5E A;  3H5J A; 
#chains in the Genus database with same CATH topology
 1V7L A;  2PKP A;  3SNP A;  1C96 A;  3H5H A;  1B0J A;  1NIT A;  1AMI A;  4KP1 A;  5ACN A;  1B0K A;  2HCU A;  1L5J A;  1C97 A;  1FGH A;  6ACN A;  2B3X A;  7ACN A;  1ACO A;  1NIS A;  3SN2 A;  4KP2 A;  1B0M A;  2B3Y A;  1AMJ A;  3Q3W A;  4NQY A;  3VBA A;  8ACN A;  3H5E A;  3H5J A; 
#chains in the Genus database with same CATH homology
 1V7L A;  2PKP A;  3SNP A;  1C96 A;  3H5H A;  1B0J A;  1NIT A;  1AMI A;  4KP1 A;  5ACN A;  1B0K A;  2HCU A;  1L5J A;  1C97 A;  1FGH A;  6ACN A;  2B3X A;  7ACN A;  1ACO A;  1NIS A;  3SN2 A;  4KP2 A;  1B0M A;  2B3Y A;  1AMJ A;  3Q3W A;  4NQY A;  3VBA A;  8ACN A;  3H5E A;  3H5J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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