6HX4A

Fab fragment of a native monomer-selective antibody in complex with alpha-1-antitrypsin
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
369
structure length
344
Chain Sequence
KITPNLAEFAFSLYRQLAHQNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFIPEAQIHEGFQELLRTLNQSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFDTEEEDFHVDQTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterisation of a monoclonal antibody conformationally-selective for native alpha-1-antitrypsin
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Alpha-1-antitrypsin
total genus 88
structure length 344
sequence length 369
chains with identical sequence B
ec nomenclature
pdb deposition date 2018-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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