1DDRA

Molecule: dihydrofolate reductase (e.c.1.5.1.3) complexed with methotrexate and urea
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords DIHYDROFOLATE REDUCTASE
publication title The effect of denaturants on protein structure.
pubmed rcsb
total genus 36
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1995-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1ddrA00
3NRRA 4KBNA 4PDJA 4M6JA 1IA1A 1RX7A 3QYLA 1RX1A 1IA4A 1JOLA 3FYWX 2W3AA 3F8ZA 3S9UA 4P3QA 3IX9A 1KMSA 1M79A 3QYOA 3OCHA 2CIGA 2W3BA 1AI9A 3D84X 2DHFA 3F0BX 4DDRA 4OSGA 3M09A 3GHVA 4EIZA 2BLCA 5HUIA 1U70A 1DDRA 1HFQA 4DFRA 4X5HA 4GH8A 1HFPA 5JA3A 2FZJA 3CD2A 4G3MA 5DXVA 3FQFA 3SRQX 3NZ9X 4ELHA 3SRWX 3FRAX 1RA2A 4Q6AA 3TQBA 2OIPA 5HF0X 3F91A 4TU5X 3K74A 4XT5A 3VCOA 3INVA 1M78A 1ZDRA 4ELBA 3FL9A 4PTJA 3DAUA 1RX5A 4G8ZX 4HOEA 1VJ3A 3S3VA 5JG0X 4ELFA 4QHVA 4H95A 4IXFX 2ITHA 3EELA 4DPHA 3NTZA 5HVBA 3IA5A 1MVSA 3UM6A 2W9TA 4P3RA 3SQYX 1RX9A 2W3WA 3QFXA 4X5GA 4DP3A 4KY8A 4KM2A 2W9GA 4NX7A 2BLBA 4X5FA 5HVEA 1DR1A 4P66A 4H98A 4KM0A 4EILA 4X5IA 1DYJA 3JWFA 5HI6A 3NZDA 1KMVA 4EJ1A 1DR4A 3FYVX 4FHBA 4M6KA 1DR2A 4Q0DA 3TD8A 5HQZA 5HT4A 2G6VA 2GD9A 3I3RA 1RX2A 3JWCA 3IRMA 3N0HA 4KYAA 1YHOA 2C2SA 1SEJA 3K45A 3CLBA 4M7UA 3RO9A 1BOZA 3EIGA 4XT7A 4ELEA 5HT5A 1DR5A 3IRNA 2ZZAA 4KLXA 4LAGX 2W9HA 1PD8A 1KLKA 4Q0EA 4I1NA 4RGCA 3JTWA 3SRSX 1RA3A 3F0XX 3IROA 1LUDA 3FQZA 4PTHA 4XE6X 2DRCA 3NZAX 1AO8A 2W3VA 2W9SA 3FY8X 7DFRA 2ANQA 3JWKA 3GYFA 2FZHA 3DGAA 3SRRX 1LY4A 3FS6A 3IA4A 3KGYA 1S3YA 3QL0A 1LY3A 1DG5A 3NXVA 1RH3A 5HSUA 1IA3A 3R33A 1E26A 4I13A 3JSUA 3ZPCA 4KL9A 3F8YA 1RX6A 4KJLA 4FGHA 1RX4A 2C2TA 5U27A 4QJZD 4P68A 3QLYA 4ELGA 3GHWA 8DFRA 5ECCA 4HA9A 3KJSA 4ECKA 2L28A 1JOMA 3Q1HA 3ROAA 1DRFA 2XW7A 4PSSA 1OHJA 4Q67A 1U72A 1DLSA 4XT4A 1RC4A 4KJKA 1J3JA 1RF7A 2O7PA 4QLGA 3TQ8A 2LF1A 2W3MA 4XT6A 2BL9A 3NXTA 4LEKX 3KY8A 1MVTA 2D0KA 5HSRA 1RE7A 1DIUA 2H2QA 1DREA 1RB2A 3QLRA 1RX8A 1QZFA 3I8AX 1DRAA 1AOEA 1RA8A 2QK8A 4LAHX 2P4GA 3OAFA 3TQAA 4KAKA 3NU0A 4LAEX 3FRFX 3HBBA 3ZPGA 3FY9X 3JW5A 3QG2A 1S3WA 2OBCA 3NXYA 4HA7A 3S7AA 3F0SX 4KY4A 1RX3A 1RG7A 3SR5X 3NXRA 1DG8A 5HQYA 2BLAA 3NXOA 3EEJA 4QI9A 3QLXA 3NZ6X 1VDRA 1DYHA 1S3VA 3FQCA 5DFRA 1OHKA 3SA1A 3HJ3A 3JVXA 4DPDA 5HPBA 2FZIA 1J3KA 3UM8A 5EAJA 4XRBA 4M7VA 1DYRA 4H97A 4KD7A 3QL3A 1CD2A 1DF7A 1RA1A 1S3UA 2KGKA 1BZFA 2HXVA 3GI2A 3M08A 4M6LA 3DRCA 3FRBX 6DFRA 2AZNA 1M7AA 1CZ3A 4KEBA 3NZBX 5FDAA 3FREX 3EX8A 3DFRA 4CD2A 4XECX 2INQA 3CSEA 4OR7A 3CL9A 1HFRA 3UM5A 5U26A 1TDRA 4H96A 1DHFA 1J3IA 3JW3A 3LG4A 4PSYA 3SRUX 1DG7A 3FL8A 1DYIA 1PD9A 3DL6A 3K47A 3QLWA 2ANOA 3JWMA 3FQ0A 5ECXA 1PDBA 4FGGA 3SH2A 3FQOA 1DHJA 3SA2A 3F0QX 1IA2A 3QLZA 3GHCA 1DAJA 1DR6A 1D1GA 5E8QA 1RA9A 3KJRA 3KFYA 3FQVA 3L3RA 1DRBA 1U71A 1DLRA 4HOFA 4QLFA 1DHIA 3E0BA 1DDSA 4X5JA 4KJJA 4IXGX 1DRHA 3DATA 3EEMA 1RD7A 1RB3A 2JYBA 3EEKA 5CC9A 4XT8A 4QJCA 1DISA 1DR3A 3TQ9A 2D5NA 3NZCX 4QLEA 4M2XA 3SAIA 4EIGA 5CCCA 3QLSA 2HQPA 3D80A 3QGTA 4NX6A 3F0UX 3K2HA 3FRDX 3SGYA 3DG8A 4G95A 4HOGA 3RG9A 5HF2X 4KFJA 1DR7A 2B3ZA 4IXED 2HM9A 4PSTA 3NXXA 2CD2A 4KNEA 3F0VX 1JUVA 3DL5A
chains in the Genus database with same CATH superfamily
3NRRA 4KBNA 4PDJA 4M6JA 1IA1A 1RX7A 3QYLA 1RX1A 1IA4A 1JOLA 3FYWX 2W3AA 3F8ZA 3S9UA 4P3QA 3IX9A 1KMSA 1M79A 3QYOA 3OCHA 2CIGA 2W3BA 1AI9A 3D84X 2DHFA 3F0BX 4DDRA 4OSGA 3M09A 3GHVA 4EIZA 2BLCA 5HUIA 1U70A 1DDRA 1HFQA 4DFRA 4X5HA 4GH8A 1HFPA 5JA3A 2FZJA 3CD2A 4G3MA 5DXVA 3FQFA 3SRQX 3NZ9X 4ELHA 3SRWX 3FRAX 1RA2A 4Q6AA 3TQBA 2OIPA 5HF0X 3F91A 4TU5X 3K74A 4XT5A 3VCOA 3INVA 1M78A 1ZDRA 4ELBA 3FL9A 4PTJA 3DAUA 1RX5A 4G8ZX 4HOEA 1VJ3A 3S3VA 5JG0X 4ELFA 4QHVA 4H95A 4IXFX 2ITHA 3EELA 4DPHA 3NTZA 5HVBA 3IA5A 1MVSA 3UM6A 2W9TA 4P3RA 3SQYX 1RX9A 2W3WA 3QFXA 4X5GA 4DP3A 4KY8A 4KM2A 2W9GA 4NX7A 2BLBA 4X5FA 5HVEA 1DR1A 4P66A 4H98A 4KM0A 4EILA 4X5IA 1DYJA 3JWFA 5HI6A 3NZDA 1KMVA 4EJ1A 1DR4A 3FYVX 4FHBA 4M6KA 1DR2A 4Q0DA 3TD8A 5HQZA 5HT4A 2G6VA 2GD9A 3I3RA 1RX2A 3JWCA 3IRMA 3N0HA 4KYAA 1YHOA 2C2SA 1SEJA 3K45A 3CLBA 4M7UA 3RO9A 1BOZA 3EIGA 4XT7A 4ELEA 5HT5A 1DR5A 3IRNA 2ZZAA 4KLXA 4LAGX 2W9HA 1PD8A 1KLKA 4Q0EA 4I1NA 4RGCA 3JTWA 3SRSX 1RA3A 3F0XX 3IROA 1LUDA 3FQZA 4PTHA 4XE6X 2DRCA 3NZAX 1AO8A 2W3VA 2W9SA 3FY8X 7DFRA 2ANQA 3JWKA 3GYFA 2FZHA 3DGAA 3SRRX 1LY4A 3FS6A 3IA4A 3KGYA 1S3YA 3QL0A 1LY3A 1DG5A 3NXVA 1RH3A 5HSUA 1IA3A 3R33A 1E26A 4I13A 3JSUA 3ZPCA 4KL9A 3F8YA 1RX6A 4KJLA 4FGHA 1RX4A 2C2TA 5U27A 4QJZD 4P68A 3QLYA 4ELGA 3GHWA 8DFRA 5ECCA 4HA9A 3KJSA 4ECKA 2L28A 1JOMA 3Q1HA 3ROAA 1DRFA 2XW7A 4PSSA 1OHJA 4Q67A 1U72A 1DLSA 4XT4A 1RC4A 4KJKA 1J3JA 1RF7A 2O7PA 4QLGA 3TQ8A 2LF1A 2W3MA 4XT6A 2BL9A 3NXTA 4LEKX 3KY8A 1MVTA 2D0KA 5HSRA 1RE7A 1DIUA 2H2QA 1DREA 1RB2A 3QLRA 1RX8A 1QZFA 3I8AX 1DRAA 1AOEA 1RA8A 2QK8A 4LAHX 2P4GA 3OAFA 3TQAA 4KAKA 3NU0A 4LAEX 3FRFX 3HBBA 3ZPGA 3FY9X 3JW5A 3QG2A 1S3WA 2OBCA 3NXYA 4HA7A 3S7AA 3F0SX 4KY4A 1RX3A 1RG7A 3SR5X 3NXRA 1DG8A 5HQYA 2BLAA 3NXOA 3EEJA 4QI9A 3QLXA 3NZ6X 1VDRA 1DYHA 1S3VA 3FQCA 5DFRA 1OHKA 3SA1A 3HJ3A 3JVXA 4DPDA 5HPBA 2FZIA 1J3KA 3UM8A 5EAJA 4XRBA 4M7VA 1DYRA 4H97A 4KD7A 3QL3A 1CD2A 1DF7A 1RA1A 1S3UA 2KGKA 1BZFA 2HXVA 3GI2A 3M08A 4M6LA 3DRCA 3FRBX 6DFRA 2AZNA 1M7AA 1CZ3A 4KEBA 3NZBX 5FDAA 3FREX 3EX8A 3DFRA 4CD2A 4XECX 2INQA 3CSEA 4OR7A 3CL9A 1HFRA 3UM5A 5U26A 1TDRA 4H96A 1DHFA 1J3IA 3JW3A 3LG4A 4PSYA 3SRUX 1DG7A 3FL8A 1DYIA 1PD9A 3DL6A 3K47A 3QLWA 2ANOA 3JWMA 3FQ0A 5ECXA 1PDBA 4FGGA 3SH2A 3FQOA 1DHJA 3SA2A 3F0QX 1IA2A 3QLZA 3GHCA 1DAJA 1DR6A 1D1GA 5E8QA 1RA9A 3KJRA 3KFYA 3FQVA 3L3RA 1DRBA 1U71A 1DLRA 4HOFA 4QLFA 1DHIA 3E0BA 1DDSA 4X5JA 4KJJA 4IXGX 1DRHA 3DATA 3EEMA 1RD7A 1RB3A 2JYBA 3EEKA 5CC9A 4XT8A 4QJCA 1DISA 1DR3A 3TQ9A 2D5NA 3NZCX 4QLEA 4M2XA 3SAIA 4EIGA 5CCCA 3QLSA 2HQPA 3D80A 3QGTA 4NX6A 3F0UX 3K2HA 3FRDX 3SGYA 3DG8A 4G95A 4HOGA 3RG9A 5HF2X 4KFJA 1DR7A 2B3ZA 4IXED 2HM9A 4PSTA 3NXXA 2CD2A 4KNEA 3F0VX 1JUVA 3DL5A
chains in the Genus database with same CATH topology
3NRRA 4KBNA 4PDJA 4M6JA 1IA1A 1RX7A 3QYLA 1RX1A 1IA4A 1JOLA 3FYWX 2W3AA 3F8ZA 3S9UA 4P3QA 3IX9A 1KMSA 1M79A 3QYOA 3OCHA 2CIGA 2W3BA 1AI9A 3D84X 2DHFA 3F0BX 4DDRA 4OSGA 3M09A 3GHVA 4EIZA 2BLCA 5HUIA 1U70A 1DDRA 1HFQA 4DFRA 4X5HA 4GH8A 1HFPA 5JA3A 2FZJA 3CD2A 4G3MA 5DXVA 3FQFA 3SRQX 3NZ9X 4ELHA 3SRWX 3FRAX 1RA2A 4Q6AA 3TQBA 2OIPA 5HF0X 3F91A 4TU5X 3K74A 4XT5A 3VCOA 3INVA 1M78A 1ZDRA 4ELBA 3FL9A 4PTJA 3DAUA 1RX5A 4G8ZX 4HOEA 1VJ3A 3S3VA 5JG0X 4ELFA 4QHVA 4H95A 4IXFX 2ITHA 3EELA 4DPHA 3NTZA 5HVBA 3IA5A 1MVSA 3UM6A 2W9TA 4P3RA 3SQYX 1RX9A 2W3WA 3QFXA 4X5GA 4DP3A 4KY8A 4KM2A 2W9GA 4NX7A 2BLBA 4X5FA 5HVEA 1DR1A 4P66A 4H98A 4KM0A 4EILA 4X5IA 1DYJA 3JWFA 5HI6A 3NZDA 1KMVA 4EJ1A 1DR4A 3FYVX 4FHBA 4M6KA 1DR2A 4Q0DA 3TD8A 5HQZA 5HT4A 2G6VA 2GD9A 3I3RA 1RX2A 3JWCA 3IRMA 3N0HA 4KYAA 1YHOA 2C2SA 1SEJA 3K45A 3CLBA 4M7UA 3RO9A 1BOZA 3EIGA 4XT7A 4ELEA 5HT5A 1DR5A 3IRNA 2ZZAA 4KLXA 4LAGX 2W9HA 1PD8A 1KLKA 4Q0EA 4I1NA 4RGCA 3JTWA 3SRSX 1RA3A 3F0XX 3IROA 1LUDA 3FQZA 4PTHA 4XE6X 2DRCA 3NZAX 1AO8A 2W3VA 2W9SA 3FY8X 7DFRA 2ANQA 3JWKA 3GYFA 2FZHA 3DGAA 3SRRX 1LY4A 3FS6A 3IA4A 3KGYA 1S3YA 3QL0A 1LY3A 1DG5A 3NXVA 1RH3A 5HSUA 1IA3A 3R33A 1E26A 4I13A 3JSUA 3ZPCA 4KL9A 3F8YA 1RX6A 4KJLA 4FGHA 1RX4A 2C2TA 5U27A 4QJZD 4P68A 3QLYA 4ELGA 3GHWA 8DFRA 5ECCA 4HA9A 3KJSA 4ECKA 2L28A 1JOMA 3Q1HA 3ROAA 1DRFA 2XW7A 4PSSA 1OHJA 4Q67A 1U72A 1DLSA 4XT4A 1RC4A 4KJKA 1J3JA 1RF7A 2O7PA 4QLGA 3TQ8A 2LF1A 2W3MA 4XT6A 2BL9A 3NXTA 4LEKX 3KY8A 1MVTA 2D0KA 5HSRA 1RE7A 1DIUA 2H2QA 1DREA 1RB2A 3QLRA 1RX8A 1QZFA 3I8AX 1DRAA 1AOEA 1RA8A 2QK8A 4LAHX 2P4GA 3OAFA 3TQAA 4KAKA 3NU0A 4LAEX 3FRFX 3HBBA 3ZPGA 3FY9X 3JW5A 3QG2A 1S3WA 2OBCA 3NXYA 4HA7A 3S7AA 3F0SX 4KY4A 1RX3A 1RG7A 3SR5X 3NXRA 1DG8A 5HQYA 2BLAA 3NXOA 3EEJA 4QI9A 3QLXA 3NZ6X 1VDRA 1DYHA 1S3VA 3FQCA 5DFRA 1OHKA 3SA1A 3HJ3A 3JVXA 4DPDA 5HPBA 2FZIA 1J3KA 3UM8A 5EAJA 4XRBA 4M7VA 1DYRA 4H97A 4KD7A 3QL3A 1CD2A 1DF7A 1RA1A 1S3UA 2KGKA 1BZFA 2HXVA 3GI2A 3M08A 4M6LA 3DRCA 3FRBX 6DFRA 2AZNA 1M7AA 1CZ3A 4KEBA 3NZBX 5FDAA 3FREX 3EX8A 3DFRA 4CD2A 4XECX 2INQA 3CSEA 4OR7A 3CL9A 1HFRA 3UM5A 5U26A 1TDRA 4H96A 1DHFA 1J3IA 3JW3A 3LG4A 4PSYA 3SRUX 1DG7A 3FL8A 1DYIA 1PD9A 3DL6A 3K47A 3QLWA 2ANOA 3JWMA 3FQ0A 5ECXA 1PDBA 4FGGA 3SH2A 3FQOA 1DHJA 3SA2A 3F0QX 1IA2A 3QLZA 3GHCA 1DAJA 1DR6A 1D1GA 5E8QA 1RA9A 3KJRA 3KFYA 3FQVA 3L3RA 1DRBA 1U71A 1DLRA 4HOFA 4QLFA 1DHIA 3E0BA 1DDSA 4X5JA 4KJJA 4IXGX 1DRHA 3DATA 3EEMA 1RD7A 1RB3A 2JYBA 3EEKA 5CC9A 4XT8A 4QJCA 1DISA 1DR3A 3TQ9A 2D5NA 3NZCX 4QLEA 4M2XA 3SAIA 4EIGA 5CCCA 3QLSA 2HQPA 3D80A 3QGTA 4NX6A 3F0UX 3K2HA 3FRDX 3SGYA 3DG8A 4G95A 4HOGA 3RG9A 5HF2X 4KFJA 1DR7A 2B3ZA 4IXED 2HM9A 4PSTA 3NXXA 2CD2A 4KNEA 3F0VX 1JUVA 3DL5A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3NRR A;  4KBN A;  4PDJ A;  4M6J A;  1IA1 A;  1RX7 A;  3QYL A;  1RX1 A;  1IA4 A;  1JOL A;  3FYW X;  2W3A A;  3F8Z A;  3S9U A;  4P3Q A;  3IX9 A;  1KMS A;  1M79 A;  3QYO A;  3OCH A;  2CIG A;  2W3B A;  1AI9 A;  3D84 X;  2DHF A;  3F0B X;  4DDR A;  4OSG A;  3M09 A;  3GHV A;  4EIZ A;  2BLC A;  5HUI A;  1U70 A;  1DDR A;  1HFQ A;  4DFR A;  4X5H A;  4GH8 A;  1HFP A;  5JA3 A;  2FZJ A;  3CD2 A;  4G3M A;  5DXV A;  3FQF A;  3SRQ X;  3NZ9 X;  4ELH A;  3SRW X;  3FRA X;  1RA2 A;  4Q6A A;  3TQB A;  2OIP A;  5HF0 X;  3F91 A;  4TU5 X;  3K74 A;  4XT5 A;  3VCO A;  3INV A;  1M78 A;  1ZDR A;  4ELB A;  3FL9 A;  4PTJ A;  3DAU A;  1RX5 A;  4G8Z X;  4HOE A;  1VJ3 A;  3S3V A;  5JG0 X;  4ELF A;  4QHV A;  4H95 A;  4IXF X;  2ITH A;  3EEL A;  4DPH A;  3NTZ A;  5HVB A;  3IA5 A;  1MVS A;  3UM6 A;  2W9T A;  4P3R A;  3SQY X;  1RX9 A;  2W3W A;  3QFX A;  4X5G A;  4DP3 A;  4KY8 A;  4KM2 A;  2W9G A;  4NX7 A;  2BLB A;  4X5F A;  5HVE A;  1DR1 A;  4P66 A;  4H98 A;  4KM0 A;  4EIL A;  4X5I A;  1DYJ A;  3JWF A;  5HI6 A;  3NZD A;  1KMV A;  4EJ1 A;  1DR4 A;  3FYV X;  4FHB A;  4M6K A;  1DR2 A;  4Q0D A;  3TD8 A;  5HQZ A;  5HT4 A;  2G6V A;  2GD9 A;  3I3R A;  1RX2 A;  3JWC A;  3IRM A;  3N0H A;  4KYA A;  1YHO A;  2C2S A;  1SEJ A;  3K45 A;  3CLB A;  4M7U A;  3RO9 A;  1BOZ A;  3EIG A;  4XT7 A;  4ELE A;  5HT5 A;  1DR5 A;  3IRN A;  2ZZA A;  4KLX A;  4LAG X;  2W9H A;  1PD8 A;  1KLK A;  4Q0E A;  4I1N A;  4RGC A;  3JTW A;  3SRS X;  1RA3 A;  3F0X X;  3IRO A;  1LUD A;  3FQZ A;  4PTH A;  4XE6 X;  2DRC A;  3NZA X;  1AO8 A;  2W3V A;  2W9S A;  3FY8 X;  7DFR A;  2ANQ A;  3JWK A;  3GYF A;  2FZH A;  3DGA A;  3SRR X;  1LY4 A;  3FS6 A;  3IA4 A;  3KGY A;  1S3Y A;  3QL0 A;  1LY3 A;  1DG5 A;  3NXV A;  1RH3 A;  5HSU A;  1IA3 A;  3R33 A;  1E26 A;  4I13 A;  3JSU A;  3ZPC A;  4KL9 A;  3F8Y A;  1RX6 A;  4KJL A;  4FGH A;  1RX4 A;  2C2T A;  5U27 A;  4QJZ D;  4P68 A;  3QLY A;  4ELG A;  3GHW A;  8DFR A;  5ECC A;  4HA9 A;  3KJS A;  4ECK A;  2L28 A;  1JOM A;  3Q1H A;  3ROA A;  1DRF A;  2XW7 A;  4PSS A;  1OHJ A;  4Q67 A;  1U72 A;  1DLS A;  4XT4 A;  1RC4 A;  4KJK A;  1J3J A;  1RF7 A;  2O7P A;  4QLG A;  3TQ8 A;  2LF1 A;  2W3M A;  4XT6 A;  2BL9 A;  3NXT A;  4LEK X;  3KY8 A;  1MVT A;  2D0K A;  5HSR A;  1RE7 A;  1DIU A;  2H2Q A;  1DRE A;  1RB2 A;  3QLR A;  1RX8 A;  1QZF A;  3I8A X;  1DRA A;  1AOE A;  1RA8 A;  2QK8 A;  4LAH X;  2P4G A;  3OAF A;  3TQA A;  4KAK A;  3NU0 A;  4LAE X;  3FRF X;  3HBB A;  3ZPG A;  3FY9 X;  3JW5 A;  3QG2 A;  1S3W A;  2OBC A;  3NXY A;  4HA7 A;  3S7A A;  3F0S X;  4KY4 A;  1RX3 A;  1RG7 A;  3SR5 X;  3NXR A;  1DG8 A;  5HQY A;  2BLA A;  3NXO A;  3EEJ A;  4QI9 A;  3QLX A;  3NZ6 X;  1VDR A;  1DYH A;  1S3V A;  3FQC A;  5DFR A;  1OHK A;  3SA1 A;  3HJ3 A;  3JVX A;  4DPD A;  5HPB A;  2FZI A;  1J3K A;  3UM8 A;  5EAJ A;  4XRB A;  4M7V A;  1DYR A;  4H97 A;  4KD7 A;  3QL3 A;  1CD2 A;  1DF7 A;  1RA1 A;  1S3U A;  2KGK A;  1BZF A;  2HXV A;  3GI2 A;  3M08 A;  4M6L A;  3DRC A;  3FRB X;  6DFR A;  2AZN A;  1M7A A;  1CZ3 A;  4KEB A;  3NZB X;  5FDA A;  3FRE X;  3EX8 A;  3DFR A;  4CD2 A;  4XEC X;  2INQ A;  3CSE A;  4OR7 A;  3CL9 A;  1HFR A;  3UM5 A;  5U26 A;  1TDR A;  4H96 A;  1DHF A;  1J3I A;  3JW3 A;  3LG4 A;  4PSY A;  3SRU X;  1DG7 A;  3FL8 A;  1DYI A;  1PD9 A;  3DL6 A;  3K47 A;  3QLW A;  2ANO A;  3JWM A;  3FQ0 A;  5ECX A;  1PDB A;  4FGG A;  3SH2 A;  3FQO A;  1DHJ A;  3SA2 A;  3F0Q X;  1IA2 A;  3QLZ A;  3GHC A;  1DAJ A;  1DR6 A;  1D1G A;  5E8Q A;  1RA9 A;  3KJR A;  3KFY A;  3FQV A;  3L3R A;  1DRB A;  1U71 A;  1DLR A;  4HOF A;  4QLF A;  1DHI A;  3E0B A;  1DDS A;  4X5J A;  4KJJ A;  4IXG X;  1DRH A;  3DAT A;  3EEM A;  1RD7 A;  1RB3 A;  2JYB A;  3EEK A;  5CC9 A;  4XT8 A;  4QJC A;  1DIS A;  1DR3 A;  3TQ9 A;  2D5N A;  3NZC X;  4QLE A;  4M2X A;  3SAI A;  4EIG A;  5CCC A;  3QLS A;  2HQP A;  3D80 A;  3QGT A;  4NX6 A;  3F0U X;  3K2H A;  3FRD X;  3SGY A;  3DG8 A;  4G95 A;  4HOG A;  3RG9 A;  5HF2 X;  4KFJ A;  1DR7 A;  2B3Z A;  4IXE D;  2HM9 A;  4PST A;  3NXX A;  2CD2 A;  4KNE A;  3F0V X;  1JUV A;  3DL5 A; 
#chains in the Genus database with same CATH topology
 3NRR A;  4KBN A;  4PDJ A;  4M6J A;  1IA1 A;  1RX7 A;  3QYL A;  1RX1 A;  1IA4 A;  1JOL A;  3FYW X;  2W3A A;  3F8Z A;  3S9U A;  4P3Q A;  3IX9 A;  1KMS A;  1M79 A;  3QYO A;  3OCH A;  2CIG A;  2W3B A;  1AI9 A;  3D84 X;  2DHF A;  3F0B X;  4DDR A;  4OSG A;  3M09 A;  3GHV A;  4EIZ A;  2BLC A;  5HUI A;  1U70 A;  1DDR A;  1HFQ A;  4DFR A;  4X5H A;  4GH8 A;  1HFP A;  5JA3 A;  2FZJ A;  3CD2 A;  4G3M A;  5DXV A;  3FQF A;  3SRQ X;  3NZ9 X;  4ELH A;  3SRW X;  3FRA X;  1RA2 A;  4Q6A A;  3TQB A;  2OIP A;  5HF0 X;  3F91 A;  4TU5 X;  3K74 A;  4XT5 A;  3VCO A;  3INV A;  1M78 A;  1ZDR A;  4ELB A;  3FL9 A;  4PTJ A;  3DAU A;  1RX5 A;  4G8Z X;  4HOE A;  1VJ3 A;  3S3V A;  5JG0 X;  4ELF A;  4QHV A;  4H95 A;  4IXF X;  2ITH A;  3EEL A;  4DPH A;  3NTZ A;  5HVB A;  3IA5 A;  1MVS A;  3UM6 A;  2W9T A;  4P3R A;  3SQY X;  1RX9 A;  2W3W A;  3QFX A;  4X5G A;  4DP3 A;  4KY8 A;  4KM2 A;  2W9G A;  4NX7 A;  2BLB A;  4X5F A;  5HVE A;  1DR1 A;  4P66 A;  4H98 A;  4KM0 A;  4EIL A;  4X5I A;  1DYJ A;  3JWF A;  5HI6 A;  3NZD A;  1KMV A;  4EJ1 A;  1DR4 A;  3FYV X;  4FHB A;  4M6K A;  1DR2 A;  4Q0D A;  3TD8 A;  5HQZ A;  5HT4 A;  2G6V A;  2GD9 A;  3I3R A;  1RX2 A;  3JWC A;  3IRM A;  3N0H A;  4KYA A;  1YHO A;  2C2S A;  1SEJ A;  3K45 A;  3CLB A;  4M7U A;  3RO9 A;  1BOZ A;  3EIG A;  4XT7 A;  4ELE A;  5HT5 A;  1DR5 A;  3IRN A;  2ZZA A;  4KLX A;  4LAG X;  2W9H A;  1PD8 A;  1KLK A;  4Q0E A;  4I1N A;  4RGC A;  3JTW A;  3SRS X;  1RA3 A;  3F0X X;  3IRO A;  1LUD A;  3FQZ A;  4PTH A;  4XE6 X;  2DRC A;  3NZA X;  1AO8 A;  2W3V A;  2W9S A;  3FY8 X;  7DFR A;  2ANQ A;  3JWK A;  3GYF A;  2FZH A;  3DGA A;  3SRR X;  1LY4 A;  3FS6 A;  3IA4 A;  3KGY A;  1S3Y A;  3QL0 A;  1LY3 A;  1DG5 A;  3NXV A;  1RH3 A;  5HSU A;  1IA3 A;  3R33 A;  1E26 A;  4I13 A;  3JSU A;  3ZPC A;  4KL9 A;  3F8Y A;  1RX6 A;  4KJL A;  4FGH A;  1RX4 A;  2C2T A;  5U27 A;  4QJZ D;  4P68 A;  3QLY A;  4ELG A;  3GHW A;  8DFR A;  5ECC A;  4HA9 A;  3KJS A;  4ECK A;  2L28 A;  1JOM A;  3Q1H A;  3ROA A;  1DRF A;  2XW7 A;  4PSS A;  1OHJ A;  4Q67 A;  1U72 A;  1DLS A;  4XT4 A;  1RC4 A;  4KJK A;  1J3J A;  1RF7 A;  2O7P A;  4QLG A;  3TQ8 A;  2LF1 A;  2W3M A;  4XT6 A;  2BL9 A;  3NXT A;  4LEK X;  3KY8 A;  1MVT A;  2D0K A;  5HSR A;  1RE7 A;  1DIU A;  2H2Q A;  1DRE A;  1RB2 A;  3QLR A;  1RX8 A;  1QZF A;  3I8A X;  1DRA A;  1AOE A;  1RA8 A;  2QK8 A;  4LAH X;  2P4G A;  3OAF A;  3TQA A;  4KAK A;  3NU0 A;  4LAE X;  3FRF X;  3HBB A;  3ZPG A;  3FY9 X;  3JW5 A;  3QG2 A;  1S3W A;  2OBC A;  3NXY A;  4HA7 A;  3S7A A;  3F0S X;  4KY4 A;  1RX3 A;  1RG7 A;  3SR5 X;  3NXR A;  1DG8 A;  5HQY A;  2BLA A;  3NXO A;  3EEJ A;  4QI9 A;  3QLX A;  3NZ6 X;  1VDR A;  1DYH A;  1S3V A;  3FQC A;  5DFR A;  1OHK A;  3SA1 A;  3HJ3 A;  3JVX A;  4DPD A;  5HPB A;  2FZI A;  1J3K A;  3UM8 A;  5EAJ A;  4XRB A;  4M7V A;  1DYR A;  4H97 A;  4KD7 A;  3QL3 A;  1CD2 A;  1DF7 A;  1RA1 A;  1S3U A;  2KGK A;  1BZF A;  2HXV A;  3GI2 A;  3M08 A;  4M6L A;  3DRC A;  3FRB X;  6DFR A;  2AZN A;  1M7A A;  1CZ3 A;  4KEB A;  3NZB X;  5FDA A;  3FRE X;  3EX8 A;  3DFR A;  4CD2 A;  4XEC X;  2INQ A;  3CSE A;  4OR7 A;  3CL9 A;  1HFR A;  3UM5 A;  5U26 A;  1TDR A;  4H96 A;  1DHF A;  1J3I A;  3JW3 A;  3LG4 A;  4PSY A;  3SRU X;  1DG7 A;  3FL8 A;  1DYI A;  1PD9 A;  3DL6 A;  3K47 A;  3QLW A;  2ANO A;  3JWM A;  3FQ0 A;  5ECX A;  1PDB A;  4FGG A;  3SH2 A;  3FQO A;  1DHJ A;  3SA2 A;  3F0Q X;  1IA2 A;  3QLZ A;  3GHC A;  1DAJ A;  1DR6 A;  1D1G A;  5E8Q A;  1RA9 A;  3KJR A;  3KFY A;  3FQV A;  3L3R A;  1DRB A;  1U71 A;  1DLR A;  4HOF A;  4QLF A;  1DHI A;  3E0B A;  1DDS A;  4X5J A;  4KJJ A;  4IXG X;  1DRH A;  3DAT A;  3EEM A;  1RD7 A;  1RB3 A;  2JYB A;  3EEK A;  5CC9 A;  4XT8 A;  4QJC A;  1DIS A;  1DR3 A;  3TQ9 A;  2D5N A;  3NZC X;  4QLE A;  4M2X A;  3SAI A;  4EIG A;  5CCC A;  3QLS A;  2HQP A;  3D80 A;  3QGT A;  4NX6 A;  3F0U X;  3K2H A;  3FRD X;  3SGY A;  3DG8 A;  4G95 A;  4HOG A;  3RG9 A;  5HF2 X;  4KFJ A;  1DR7 A;  2B3Z A;  4IXE D;  2HM9 A;  4PST A;  3NXX A;  2CD2 A;  4KNE A;  3F0V X;  1JUV A;  3DL5 A; 
#chains in the Genus database with same CATH homology
 3NRR A;  4KBN A;  4PDJ A;  4M6J A;  1IA1 A;  1RX7 A;  3QYL A;  1RX1 A;  1IA4 A;  1JOL A;  3FYW X;  2W3A A;  3F8Z A;  3S9U A;  4P3Q A;  3IX9 A;  1KMS A;  1M79 A;  3QYO A;  3OCH A;  2CIG A;  2W3B A;  1AI9 A;  3D84 X;  2DHF A;  3F0B X;  4DDR A;  4OSG A;  3M09 A;  3GHV A;  4EIZ A;  2BLC A;  5HUI A;  1U70 A;  1DDR A;  1HFQ A;  4DFR A;  4X5H A;  4GH8 A;  1HFP A;  5JA3 A;  2FZJ A;  3CD2 A;  4G3M A;  5DXV A;  3FQF A;  3SRQ X;  3NZ9 X;  4ELH A;  3SRW X;  3FRA X;  1RA2 A;  4Q6A A;  3TQB A;  2OIP A;  5HF0 X;  3F91 A;  4TU5 X;  3K74 A;  4XT5 A;  3VCO A;  3INV A;  1M78 A;  1ZDR A;  4ELB A;  3FL9 A;  4PTJ A;  3DAU A;  1RX5 A;  4G8Z X;  4HOE A;  1VJ3 A;  3S3V A;  5JG0 X;  4ELF A;  4QHV A;  4H95 A;  4IXF X;  2ITH A;  3EEL A;  4DPH A;  3NTZ A;  5HVB A;  3IA5 A;  1MVS A;  3UM6 A;  2W9T A;  4P3R A;  3SQY X;  1RX9 A;  2W3W A;  3QFX A;  4X5G A;  4DP3 A;  4KY8 A;  4KM2 A;  2W9G A;  4NX7 A;  2BLB A;  4X5F A;  5HVE A;  1DR1 A;  4P66 A;  4H98 A;  4KM0 A;  4EIL A;  4X5I A;  1DYJ A;  3JWF A;  5HI6 A;  3NZD A;  1KMV A;  4EJ1 A;  1DR4 A;  3FYV X;  4FHB A;  4M6K A;  1DR2 A;  4Q0D A;  3TD8 A;  5HQZ A;  5HT4 A;  2G6V A;  2GD9 A;  3I3R A;  1RX2 A;  3JWC A;  3IRM A;  3N0H A;  4KYA A;  1YHO A;  2C2S A;  1SEJ A;  3K45 A;  3CLB A;  4M7U A;  3RO9 A;  1BOZ A;  3EIG A;  4XT7 A;  4ELE A;  5HT5 A;  1DR5 A;  3IRN A;  2ZZA A;  4KLX A;  4LAG X;  2W9H A;  1PD8 A;  1KLK A;  4Q0E A;  4I1N A;  4RGC A;  3JTW A;  3SRS X;  1RA3 A;  3F0X X;  3IRO A;  1LUD A;  3FQZ A;  4PTH A;  4XE6 X;  2DRC A;  3NZA X;  1AO8 A;  2W3V A;  2W9S A;  3FY8 X;  7DFR A;  2ANQ A;  3JWK A;  3GYF A;  2FZH A;  3DGA A;  3SRR X;  1LY4 A;  3FS6 A;  3IA4 A;  3KGY A;  1S3Y A;  3QL0 A;  1LY3 A;  1DG5 A;  3NXV A;  1RH3 A;  5HSU A;  1IA3 A;  3R33 A;  1E26 A;  4I13 A;  3JSU A;  3ZPC A;  4KL9 A;  3F8Y A;  1RX6 A;  4KJL A;  4FGH A;  1RX4 A;  2C2T A;  5U27 A;  4QJZ D;  4P68 A;  3QLY A;  4ELG A;  3GHW A;  8DFR A;  5ECC A;  4HA9 A;  3KJS A;  4ECK A;  2L28 A;  1JOM A;  3Q1H A;  3ROA A;  1DRF A;  2XW7 A;  4PSS A;  1OHJ A;  4Q67 A;  1U72 A;  1DLS A;  4XT4 A;  1RC4 A;  4KJK A;  1J3J A;  1RF7 A;  2O7P A;  4QLG A;  3TQ8 A;  2LF1 A;  2W3M A;  4XT6 A;  2BL9 A;  3NXT A;  4LEK X;  3KY8 A;  1MVT A;  2D0K A;  5HSR A;  1RE7 A;  1DIU A;  2H2Q A;  1DRE A;  1RB2 A;  3QLR A;  1RX8 A;  1QZF A;  3I8A X;  1DRA A;  1AOE A;  1RA8 A;  2QK8 A;  4LAH X;  2P4G A;  3OAF A;  3TQA A;  4KAK A;  3NU0 A;  4LAE X;  3FRF X;  3HBB A;  3ZPG A;  3FY9 X;  3JW5 A;  3QG2 A;  1S3W A;  2OBC A;  3NXY A;  4HA7 A;  3S7A A;  3F0S X;  4KY4 A;  1RX3 A;  1RG7 A;  3SR5 X;  3NXR A;  1DG8 A;  5HQY A;  2BLA A;  3NXO A;  3EEJ A;  4QI9 A;  3QLX A;  3NZ6 X;  1VDR A;  1DYH A;  1S3V A;  3FQC A;  5DFR A;  1OHK A;  3SA1 A;  3HJ3 A;  3JVX A;  4DPD A;  5HPB A;  2FZI A;  1J3K A;  3UM8 A;  5EAJ A;  4XRB A;  4M7V A;  1DYR A;  4H97 A;  4KD7 A;  3QL3 A;  1CD2 A;  1DF7 A;  1RA1 A;  1S3U A;  2KGK A;  1BZF A;  2HXV A;  3GI2 A;  3M08 A;  4M6L A;  3DRC A;  3FRB X;  6DFR A;  2AZN A;  1M7A A;  1CZ3 A;  4KEB A;  3NZB X;  5FDA A;  3FRE X;  3EX8 A;  3DFR A;  4CD2 A;  4XEC X;  2INQ A;  3CSE A;  4OR7 A;  3CL9 A;  1HFR A;  3UM5 A;  5U26 A;  1TDR A;  4H96 A;  1DHF A;  1J3I A;  3JW3 A;  3LG4 A;  4PSY A;  3SRU X;  1DG7 A;  3FL8 A;  1DYI A;  1PD9 A;  3DL6 A;  3K47 A;  3QLW A;  2ANO A;  3JWM A;  3FQ0 A;  5ECX A;  1PDB A;  4FGG A;  3SH2 A;  3FQO A;  1DHJ A;  3SA2 A;  3F0Q X;  1IA2 A;  3QLZ A;  3GHC A;  1DAJ A;  1DR6 A;  1D1G A;  5E8Q A;  1RA9 A;  3KJR A;  3KFY A;  3FQV A;  3L3R A;  1DRB A;  1U71 A;  1DLR A;  4HOF A;  4QLF A;  1DHI A;  3E0B A;  1DDS A;  4X5J A;  4KJJ A;  4IXG X;  1DRH A;  3DAT A;  3EEM A;  1RD7 A;  1RB3 A;  2JYB A;  3EEK A;  5CC9 A;  4XT8 A;  4QJC A;  1DIS A;  1DR3 A;  3TQ9 A;  2D5N A;  3NZC X;  4QLE A;  4M2X A;  3SAI A;  4EIG A;  5CCC A;  3QLS A;  2HQP A;  3D80 A;  3QGT A;  4NX6 A;  3F0U X;  3K2H A;  3FRD X;  3SGY A;  3DG8 A;  4G95 A;  4HOG A;  3RG9 A;  5HF2 X;  4KFJ A;  1DR7 A;  2B3Z A;  4IXE D;  2HM9 A;  4PST A;  3NXX A;  2CD2 A;  4KNE A;  3F0V X;  1JUV A;  3DL5 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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