1RX8A

Dihydrofolate reductase complexed with folate and 2'-monophosphoadenosine 5'-diphosphoribose
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords DIHYDROFOLATE REDUCTASE
publication title Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
pubmed doi rcsb
source organism Escherichia coli
total genus 44
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-10-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1rx8A00
3KJSA 3KGYA 3QLWA 4M6KA 2FZJA 1KMVA 2W9GA 4CD2A 3CSEA 3FRFX 1DRFA 3NZ9X 1PD9A 3E0BA 5EAJA 1KMSA 3ROAA 3JW3A 3QYLA 4EIZA 5HSUA 4IXED 4IXFX 1RX3A 3D80A 2L28A 3IRMA 3QLRA 4OSGA 1J3JA 4XT4A 3FQVA 3FY9X 3FQOA 4PTJA 3DGAA 4LAEX 5DFRA 3FQCA 3GI2A 4KJKA 4XRBA 1BOZA 4HOGA 3TQBA 1ZDRA 3SR5X 2W9HA 1M79A 3FY8X 4G95A 4HOFA 3DL5A 2BL9A 4HA9A 1JOLA 3JWFA 3Q1HA 4P3RA 1RX7A 4P66A 3SRQX 1RX4A 3EEKA 1DREA 2QK8A 1S3UA 3S7AA 3FRAX 4Q0DA 3QLSA 1DIUA 2CD2A 1LUDA 1VJ3A 3NXRA 3QYOA 1DF7A 2INQA 4I1NA 3S3VA 3QLZA 1M78A 4P3QA 3JSUA 1RA3A 3EEMA 3NXYA 4XT5A 5HVEA 2LF1A 3JWMA 1DG7A 1RX5A 3F0BX 3FRDX 1RB3A 2W3AA 4H96A 5ECXA 7DFRA 1DYJA 4KM0A 1CZ3A 2OBCA 3KFYA 1PD8A 1RE7A 3CLBA 3FL9A 3VCOA 1RA8A 3HBBA 2CIGA 3GHCA 4Q6AA 1DHJA 1RA1A 3IX9A 4KD7A 4DPDA 1DHFA 4PDJA 2W3VA 1DDSA 4XECX 3SA1A 4DP3A 1RX9A 4XT7A 4PTHA 4ELBA 1TDRA 3EIGA 1DLSA 1DR2A 1LY4A 3F8ZA 3UM6A 1DISA 5ECCA 3IA4A 3I8AX 3QLYA 3QL0A 1DG8A 1MVTA 3F0SX 3SRRX 3DRCA 4EILA 2ZZAA 4KL9A 4QLFA 1IA4A 1IA3A 2HXVA 2D5NA 4P68A 4OR7A 3FYWX 4FGGA 5CCCA 1M7AA 4ELFA 5HQZA 3JWKA 3K47A 3CL9A 5U26A 1DHIA 4XT8A 5JA3A 1AOEA 3DFRA 5JG0X 3D84X 3DL6A 4FHBA 1DYIA 1AI9A 3NXTA 4KM2A 4X5IA 3I3RA 3NXVA 3INVA 3NXOA 2HQPA 3K74A 1CD2A 4KEBA 3F0UX 2DRCA 4KLXA 3RG9A 1HFPA 3FYVX 1RA2A 8DFRA 4PSYA 3NTZA 1IA2A 1DRAA 3FS6A 3ZPCA 1DR5A 3JTWA 3GYFA 1BZFA 3NZAX 3JVXA 3M08A 1J3KA 2AZNA 3F0QX 5U27A 1YHOA 1OHKA 4QI9A 3TQ9A 4ELGA 4LEKX 4XE6X 4KY4A 3SAIA 1RX1A 2W3BA 1RX6A 1RX8A 1RB2A 5DXVA 1DAJA 3NZDA 1U71A 1RX2A 2W9SA 3QFXA 3TQ8A 1JUVA 3SRUX 1U70A 3IA5A 2ANQA 2ITHA 2W3WA 1RH3A 3SRSX 3TD8A 4NX6A 1U72A 3NU0A 5HF0X 1D1GA 1KLKA 3SGYA 3N0HA 4QLGA 1DR4A 1S3VA 1S3WA 3FRBX 4DDRA 5HT5A 4KFJA 2D0KA 1PDBA 3GHVA 4DPHA 3SRWX 4M6JA 4ECKA 4KBNA 2DHFA 3K45A 4ELHA 1MVSA 1DR6A 4M6LA 4KAKA 4M7VA 3R33A 2XW7A 3QLXA 1IA1A 2C2TA 4PSTA 3FQFA 1RA9A 3KJRA 4H95A 3IRNA 3L3RA 3NZCX 3DAUA 1SEJA 3EELA 3DATA 4X5HA 3SQYX 4X5JA 1AO8A 3NRRA 5HI6A 2BLBA 1DDRA 2ANOA 2GD9A 1LY3A 4KY8A 4Q0EA 6DFRA 4QJCA 3M09A 1DR1A 4QHVA 3SA2A 1OHJA 4LAHX 2H2QA 1JOMA 3SH2A 4TU5X 3NXXA 4QLEA 4KJJA 5FDAA 3S9UA 3UM8A 4KJLA 3OAFA 3ZPGA 5E8QA 5HVBA 4X5GA 4G8ZX 3NZBX 1S3YA 3F0VX 3CD2A 1DYRA 3F8YA 1RG7A 5HF2X 1DLRA 3IROA 4IXGX 3QL3A 4NX7A 2W3MA 4KNEA 3GHWA 1VDRA 2OIPA 2W9TA 2P4GA 3KY8A 4LAGX 1DYHA 1DRHA 2C2SA 4HOEA 5CC9A 5HSRA 2G6VA 1RD7A 5HUIA 1RF7A 2FZHA 2O7PA 4X5FA 3FQ0A 4HA7A 4DFRA 2BLCA 3TQAA 1RC4A 1DRBA 1DR3A 2JYBA 4EIGA 3DG8A 3OCHA 3JW5A 4QJZD 4PSSA 3UM5A 2B3ZA 4M7UA 3EX8A 3LG4A 1DR7A 3F91A 4GH8A 5HPBA 1HFQA 1HFRA 3QG2A 3FREX 3RO9A 3HJ3A 2KGKA 3NZ6X 5HQYA 4EJ1A 1J3IA 2FZIA 1QZFA 3QGTA 3EEJA 4KYAA 4I13A 3FL8A 4G3MA 4H97A 5HT4A 4RGCA 4M2XA 3JWCA 2BLAA 1E26A 3K2HA 4Q67A 4XT6A 2HM9A 3FQZA 4FGHA 4ELEA 3F0XX 1DG5A 4H98A
chains in the Genus database with same CATH superfamily
3KJSA 3KGYA 3QLWA 4M6KA 2FZJA 1KMVA 2W9GA 4CD2A 3CSEA 3FRFX 1DRFA 3NZ9X 1PD9A 3E0BA 5EAJA 1KMSA 3ROAA 3JW3A 3QYLA 4EIZA 5HSUA 4IXED 4IXFX 1RX3A 3D80A 2L28A 3IRMA 3QLRA 4OSGA 1J3JA 4XT4A 3FQVA 3FY9X 3FQOA 4PTJA 3DGAA 4LAEX 5DFRA 3FQCA 3GI2A 4KJKA 4XRBA 1BOZA 4HOGA 3TQBA 1ZDRA 3SR5X 2W9HA 1M79A 3FY8X 4G95A 4HOFA 3DL5A 2BL9A 4HA9A 1JOLA 3JWFA 3Q1HA 4P3RA 1RX7A 4P66A 3SRQX 1RX4A 3EEKA 1DREA 2QK8A 1S3UA 3S7AA 3FRAX 4Q0DA 3QLSA 1DIUA 2CD2A 1LUDA 1VJ3A 3NXRA 3QYOA 1DF7A 2INQA 4I1NA 3S3VA 3QLZA 1M78A 4P3QA 3JSUA 1RA3A 3EEMA 3NXYA 4XT5A 5HVEA 2LF1A 3JWMA 1DG7A 1RX5A 3F0BX 3FRDX 1RB3A 2W3AA 4H96A 5ECXA 7DFRA 1DYJA 4KM0A 1CZ3A 2OBCA 3KFYA 1PD8A 1RE7A 3CLBA 3FL9A 3VCOA 1RA8A 3HBBA 2CIGA 3GHCA 4Q6AA 1DHJA 1RA1A 3IX9A 4KD7A 4DPDA 1DHFA 4PDJA 2W3VA 1DDSA 4XECX 3SA1A 4DP3A 1RX9A 4XT7A 4PTHA 4ELBA 1TDRA 3EIGA 1DLSA 1DR2A 1LY4A 3F8ZA 3UM6A 1DISA 5ECCA 3IA4A 3I8AX 3QLYA 3QL0A 1DG8A 1MVTA 3F0SX 3SRRX 3DRCA 4EILA 2ZZAA 4KL9A 4QLFA 1IA4A 1IA3A 2HXVA 2D5NA 4P68A 4OR7A 3FYWX 4FGGA 5CCCA 1M7AA 4ELFA 5HQZA 3JWKA 3K47A 3CL9A 5U26A 1DHIA 4XT8A 5JA3A 1AOEA 3DFRA 5JG0X 3D84X 3DL6A 4FHBA 1DYIA 1AI9A 3NXTA 4KM2A 4X5IA 3I3RA 3NXVA 3INVA 3NXOA 2HQPA 3K74A 1CD2A 4KEBA 3F0UX 2DRCA 4KLXA 3RG9A 1HFPA 3FYVX 1RA2A 8DFRA 4PSYA 3NTZA 1IA2A 1DRAA 3FS6A 3ZPCA 1DR5A 3JTWA 3GYFA 1BZFA 3NZAX 3JVXA 3M08A 1J3KA 2AZNA 3F0QX 5U27A 1YHOA 1OHKA 4QI9A 3TQ9A 4ELGA 4LEKX 4XE6X 4KY4A 3SAIA 1RX1A 2W3BA 1RX6A 1RX8A 1RB2A 5DXVA 1DAJA 3NZDA 1U71A 1RX2A 2W9SA 3QFXA 3TQ8A 1JUVA 3SRUX 1U70A 3IA5A 2ANQA 2ITHA 2W3WA 1RH3A 3SRSX 3TD8A 4NX6A 1U72A 3NU0A 5HF0X 1D1GA 1KLKA 3SGYA 3N0HA 4QLGA 1DR4A 1S3VA 1S3WA 3FRBX 4DDRA 5HT5A 4KFJA 2D0KA 1PDBA 3GHVA 4DPHA 3SRWX 4M6JA 4ECKA 4KBNA 2DHFA 3K45A 4ELHA 1MVSA 1DR6A 4M6LA 4KAKA 4M7VA 3R33A 2XW7A 3QLXA 1IA1A 2C2TA 4PSTA 3FQFA 1RA9A 3KJRA 4H95A 3IRNA 3L3RA 3NZCX 3DAUA 1SEJA 3EELA 3DATA 4X5HA 3SQYX 4X5JA 1AO8A 3NRRA 5HI6A 2BLBA 1DDRA 2ANOA 2GD9A 1LY3A 4KY8A 4Q0EA 6DFRA 4QJCA 3M09A 1DR1A 4QHVA 3SA2A 1OHJA 4LAHX 2H2QA 1JOMA 3SH2A 4TU5X 3NXXA 4QLEA 4KJJA 5FDAA 3S9UA 3UM8A 4KJLA 3OAFA 3ZPGA 5E8QA 5HVBA 4X5GA 4G8ZX 3NZBX 1S3YA 3F0VX 3CD2A 1DYRA 3F8YA 1RG7A 5HF2X 1DLRA 3IROA 4IXGX 3QL3A 4NX7A 2W3MA 4KNEA 3GHWA 1VDRA 2OIPA 2W9TA 2P4GA 3KY8A 4LAGX 1DYHA 1DRHA 2C2SA 4HOEA 5CC9A 5HSRA 2G6VA 1RD7A 5HUIA 1RF7A 2FZHA 2O7PA 4X5FA 3FQ0A 4HA7A 4DFRA 2BLCA 3TQAA 1RC4A 1DRBA 1DR3A 2JYBA 4EIGA 3DG8A 3OCHA 3JW5A 4QJZD 4PSSA 3UM5A 2B3ZA 4M7UA 3EX8A 3LG4A 1DR7A 3F91A 4GH8A 5HPBA 1HFQA 1HFRA 3QG2A 3FREX 3RO9A 3HJ3A 2KGKA 3NZ6X 5HQYA 4EJ1A 1J3IA 2FZIA 1QZFA 3QGTA 3EEJA 4KYAA 4I13A 3FL8A 4G3MA 4H97A 5HT4A 4RGCA 4M2XA 3JWCA 2BLAA 1E26A 3K2HA 4Q67A 4XT6A 2HM9A 3FQZA 4FGHA 4ELEA 3F0XX 1DG5A 4H98A
chains in the Genus database with same CATH topology
3KJSA 3KGYA 3QLWA 4M6KA 2FZJA 1KMVA 2W9GA 4CD2A 3CSEA 3FRFX 1DRFA 3NZ9X 1PD9A 3E0BA 5EAJA 1KMSA 3ROAA 3JW3A 3QYLA 4EIZA 5HSUA 4IXED 4IXFX 1RX3A 3D80A 2L28A 3IRMA 3QLRA 4OSGA 1J3JA 4XT4A 3FQVA 3FY9X 3FQOA 4PTJA 3DGAA 4LAEX 5DFRA 3FQCA 3GI2A 4KJKA 4XRBA 1BOZA 4HOGA 3TQBA 1ZDRA 3SR5X 2W9HA 1M79A 3FY8X 4G95A 4HOFA 3DL5A 2BL9A 4HA9A 1JOLA 3JWFA 3Q1HA 4P3RA 1RX7A 4P66A 3SRQX 1RX4A 3EEKA 1DREA 2QK8A 1S3UA 3S7AA 3FRAX 4Q0DA 3QLSA 1DIUA 2CD2A 1LUDA 1VJ3A 3NXRA 3QYOA 1DF7A 2INQA 4I1NA 3S3VA 3QLZA 1M78A 4P3QA 3JSUA 1RA3A 3EEMA 3NXYA 4XT5A 5HVEA 2LF1A 3JWMA 1DG7A 1RX5A 3F0BX 3FRDX 1RB3A 2W3AA 4H96A 5ECXA 7DFRA 1DYJA 4KM0A 1CZ3A 2OBCA 3KFYA 1PD8A 1RE7A 3CLBA 3FL9A 3VCOA 1RA8A 3HBBA 2CIGA 3GHCA 4Q6AA 1DHJA 1RA1A 3IX9A 4KD7A 4DPDA 1DHFA 4PDJA 2W3VA 1DDSA 4XECX 3SA1A 4DP3A 1RX9A 4XT7A 4PTHA 4ELBA 1TDRA 3EIGA 1DLSA 1DR2A 1LY4A 3F8ZA 3UM6A 1DISA 5ECCA 3IA4A 3I8AX 3QLYA 3QL0A 1DG8A 1MVTA 3F0SX 3SRRX 3DRCA 4EILA 2ZZAA 4KL9A 4QLFA 1IA4A 1IA3A 2HXVA 2D5NA 4P68A 4OR7A 3FYWX 4FGGA 5CCCA 1M7AA 4ELFA 5HQZA 3JWKA 3K47A 3CL9A 5U26A 1DHIA 4XT8A 5JA3A 1AOEA 3DFRA 5JG0X 3D84X 3DL6A 4FHBA 1DYIA 1AI9A 3NXTA 4KM2A 4X5IA 3I3RA 3NXVA 3INVA 3NXOA 2HQPA 3K74A 1CD2A 4KEBA 3F0UX 2DRCA 4KLXA 3RG9A 1HFPA 3FYVX 1RA2A 8DFRA 4PSYA 3NTZA 1IA2A 1DRAA 3FS6A 3ZPCA 1DR5A 3JTWA 3GYFA 1BZFA 3NZAX 3JVXA 3M08A 1J3KA 2AZNA 3F0QX 5U27A 1YHOA 1OHKA 4QI9A 3TQ9A 4ELGA 4LEKX 4XE6X 4KY4A 3SAIA 1RX1A 2W3BA 1RX6A 1RX8A 1RB2A 5DXVA 1DAJA 3NZDA 1U71A 1RX2A 2W9SA 3QFXA 3TQ8A 1JUVA 3SRUX 1U70A 3IA5A 2ANQA 2ITHA 2W3WA 1RH3A 3SRSX 3TD8A 4NX6A 1U72A 3NU0A 5HF0X 1D1GA 1KLKA 3SGYA 3N0HA 4QLGA 1DR4A 1S3VA 1S3WA 3FRBX 4DDRA 5HT5A 4KFJA 2D0KA 1PDBA 3GHVA 4DPHA 3SRWX 4M6JA 4ECKA 4KBNA 2DHFA 3K45A 4ELHA 1MVSA 1DR6A 4M6LA 4KAKA 4M7VA 3R33A 2XW7A 3QLXA 1IA1A 2C2TA 4PSTA 3FQFA 1RA9A 3KJRA 4H95A 3IRNA 3L3RA 3NZCX 3DAUA 1SEJA 3EELA 3DATA 4X5HA 3SQYX 4X5JA 1AO8A 3NRRA 5HI6A 2BLBA 1DDRA 2ANOA 2GD9A 1LY3A 4KY8A 4Q0EA 6DFRA 4QJCA 3M09A 1DR1A 4QHVA 3SA2A 1OHJA 4LAHX 2H2QA 1JOMA 3SH2A 4TU5X 3NXXA 4QLEA 4KJJA 5FDAA 3S9UA 3UM8A 4KJLA 3OAFA 3ZPGA 5E8QA 5HVBA 4X5GA 4G8ZX 3NZBX 1S3YA 3F0VX 3CD2A 1DYRA 3F8YA 1RG7A 5HF2X 1DLRA 3IROA 4IXGX 3QL3A 4NX7A 2W3MA 4KNEA 3GHWA 1VDRA 2OIPA 2W9TA 2P4GA 3KY8A 4LAGX 1DYHA 1DRHA 2C2SA 4HOEA 5CC9A 5HSRA 2G6VA 1RD7A 5HUIA 1RF7A 2FZHA 2O7PA 4X5FA 3FQ0A 4HA7A 4DFRA 2BLCA 3TQAA 1RC4A 1DRBA 1DR3A 2JYBA 4EIGA 3DG8A 3OCHA 3JW5A 4QJZD 4PSSA 3UM5A 2B3ZA 4M7UA 3EX8A 3LG4A 1DR7A 3F91A 4GH8A 5HPBA 1HFQA 1HFRA 3QG2A 3FREX 3RO9A 3HJ3A 2KGKA 3NZ6X 5HQYA 4EJ1A 1J3IA 2FZIA 1QZFA 3QGTA 3EEJA 4KYAA 4I13A 3FL8A 4G3MA 4H97A 5HT4A 4RGCA 4M2XA 3JWCA 2BLAA 1E26A 3K2HA 4Q67A 4XT6A 2HM9A 3FQZA 4FGHA 4ELEA 3F0XX 1DG5A 4H98A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3KJS A;  3KGY A;  3QLW A;  4M6K A;  2FZJ A;  1KMV A;  2W9G A;  4CD2 A;  3CSE A;  3FRF X;  1DRF A;  3NZ9 X;  1PD9 A;  3E0B A;  5EAJ A;  1KMS A;  3ROA A;  3JW3 A;  3QYL A;  4EIZ A;  5HSU A;  4IXE D;  4IXF X;  1RX3 A;  3D80 A;  2L28 A;  3IRM A;  3QLR A;  4OSG A;  1J3J A;  4XT4 A;  3FQV A;  3FY9 X;  3FQO A;  4PTJ A;  3DGA A;  4LAE X;  5DFR A;  3FQC A;  3GI2 A;  4KJK A;  4XRB A;  1BOZ A;  4HOG A;  3TQB A;  1ZDR A;  3SR5 X;  2W9H A;  1M79 A;  3FY8 X;  4G95 A;  4HOF A;  3DL5 A;  2BL9 A;  4HA9 A;  1JOL A;  3JWF A;  3Q1H A;  4P3R A;  1RX7 A;  4P66 A;  3SRQ X;  1RX4 A;  3EEK A;  1DRE A;  2QK8 A;  1S3U A;  3S7A A;  3FRA X;  4Q0D A;  3QLS A;  1DIU A;  2CD2 A;  1LUD A;  1VJ3 A;  3NXR A;  3QYO A;  1DF7 A;  2INQ A;  4I1N A;  3S3V A;  3QLZ A;  1M78 A;  4P3Q A;  3JSU A;  1RA3 A;  3EEM A;  3NXY A;  4XT5 A;  5HVE A;  2LF1 A;  3JWM A;  1DG7 A;  1RX5 A;  3F0B X;  3FRD X;  1RB3 A;  2W3A A;  4H96 A;  5ECX A;  7DFR A;  1DYJ A;  4KM0 A;  1CZ3 A;  2OBC A;  3KFY A;  1PD8 A;  1RE7 A;  3CLB A;  3FL9 A;  3VCO A;  1RA8 A;  3HBB A;  2CIG A;  3GHC A;  4Q6A A;  1DHJ A;  1RA1 A;  3IX9 A;  4KD7 A;  4DPD A;  1DHF A;  4PDJ A;  2W3V A;  1DDS A;  4XEC X;  3SA1 A;  4DP3 A;  1RX9 A;  4XT7 A;  4PTH A;  4ELB A;  1TDR A;  3EIG A;  1DLS A;  1DR2 A;  1LY4 A;  3F8Z A;  3UM6 A;  1DIS A;  5ECC A;  3IA4 A;  3I8A X;  3QLY A;  3QL0 A;  1DG8 A;  1MVT A;  3F0S X;  3SRR X;  3DRC A;  4EIL A;  2ZZA A;  4KL9 A;  4QLF A;  1IA4 A;  1IA3 A;  2HXV A;  2D5N A;  4P68 A;  4OR7 A;  3FYW X;  4FGG A;  5CCC A;  1M7A A;  4ELF A;  5HQZ A;  3JWK A;  3K47 A;  3CL9 A;  5U26 A;  1DHI A;  4XT8 A;  5JA3 A;  1AOE A;  3DFR A;  5JG0 X;  3D84 X;  3DL6 A;  4FHB A;  1DYI A;  1AI9 A;  3NXT A;  4KM2 A;  4X5I A;  3I3R A;  3NXV A;  3INV A;  3NXO A;  2HQP A;  3K74 A;  1CD2 A;  4KEB A;  3F0U X;  2DRC A;  4KLX A;  3RG9 A;  1HFP A;  3FYV X;  1RA2 A;  8DFR A;  4PSY A;  3NTZ A;  1IA2 A;  1DRA A;  3FS6 A;  3ZPC A;  1DR5 A;  3JTW A;  3GYF A;  1BZF A;  3NZA X;  3JVX A;  3M08 A;  1J3K A;  2AZN A;  3F0Q X;  5U27 A;  1YHO A;  1OHK A;  4QI9 A;  3TQ9 A;  4ELG A;  4LEK X;  4XE6 X;  4KY4 A;  3SAI A;  1RX1 A;  2W3B A;  1RX6 A;  1RX8 A;  1RB2 A;  5DXV A;  1DAJ A;  3NZD A;  1U71 A;  1RX2 A;  2W9S A;  3QFX A;  3TQ8 A;  1JUV A;  3SRU X;  1U70 A;  3IA5 A;  2ANQ A;  2ITH A;  2W3W A;  1RH3 A;  3SRS X;  3TD8 A;  4NX6 A;  1U72 A;  3NU0 A;  5HF0 X;  1D1G A;  1KLK A;  3SGY A;  3N0H A;  4QLG A;  1DR4 A;  1S3V A;  1S3W A;  3FRB X;  4DDR A;  5HT5 A;  4KFJ A;  2D0K A;  1PDB A;  3GHV A;  4DPH A;  3SRW X;  4M6J A;  4ECK A;  4KBN A;  2DHF A;  3K45 A;  4ELH A;  1MVS A;  1DR6 A;  4M6L A;  4KAK A;  4M7V A;  3R33 A;  2XW7 A;  3QLX A;  1IA1 A;  2C2T A;  4PST A;  3FQF A;  1RA9 A;  3KJR A;  4H95 A;  3IRN A;  3L3R A;  3NZC X;  3DAU A;  1SEJ A;  3EEL A;  3DAT A;  4X5H A;  3SQY X;  4X5J A;  1AO8 A;  3NRR A;  5HI6 A;  2BLB A;  1DDR A;  2ANO A;  2GD9 A;  1LY3 A;  4KY8 A;  4Q0E A;  6DFR A;  4QJC A;  3M09 A;  1DR1 A;  4QHV A;  3SA2 A;  1OHJ A;  4LAH X;  2H2Q A;  1JOM A;  3SH2 A;  4TU5 X;  3NXX A;  4QLE A;  4KJJ A;  5FDA A;  3S9U A;  3UM8 A;  4KJL A;  3OAF A;  3ZPG A;  5E8Q A;  5HVB A;  4X5G A;  4G8Z X;  3NZB X;  1S3Y A;  3F0V X;  3CD2 A;  1DYR A;  3F8Y A;  1RG7 A;  5HF2 X;  1DLR A;  3IRO A;  4IXG X;  3QL3 A;  4NX7 A;  2W3M A;  4KNE A;  3GHW A;  1VDR A;  2OIP A;  2W9T A;  2P4G A;  3KY8 A;  4LAG X;  1DYH A;  1DRH A;  2C2S A;  4HOE A;  5CC9 A;  5HSR A;  2G6V A;  1RD7 A;  5HUI A;  1RF7 A;  2FZH A;  2O7P A;  4X5F A;  3FQ0 A;  4HA7 A;  4DFR A;  2BLC A;  3TQA A;  1RC4 A;  1DRB A;  1DR3 A;  2JYB A;  4EIG A;  3DG8 A;  3OCH A;  3JW5 A;  4QJZ D;  4PSS A;  3UM5 A;  2B3Z A;  4M7U A;  3EX8 A;  3LG4 A;  1DR7 A;  3F91 A;  4GH8 A;  5HPB A;  1HFQ A;  1HFR A;  3QG2 A;  3FRE X;  3RO9 A;  3HJ3 A;  2KGK A;  3NZ6 X;  5HQY A;  4EJ1 A;  1J3I A;  2FZI A;  1QZF A;  3QGT A;  3EEJ A;  4KYA A;  4I13 A;  3FL8 A;  4G3M A;  4H97 A;  5HT4 A;  4RGC A;  4M2X A;  3JWC A;  2BLA A;  1E26 A;  3K2H A;  4Q67 A;  4XT6 A;  2HM9 A;  3FQZ A;  4FGH A;  4ELE A;  3F0X X;  1DG5 A;  4H98 A; 
#chains in the Genus database with same CATH topology
 3KJS A;  3KGY A;  3QLW A;  4M6K A;  2FZJ A;  1KMV A;  2W9G A;  4CD2 A;  3CSE A;  3FRF X;  1DRF A;  3NZ9 X;  1PD9 A;  3E0B A;  5EAJ A;  1KMS A;  3ROA A;  3JW3 A;  3QYL A;  4EIZ A;  5HSU A;  4IXE D;  4IXF X;  1RX3 A;  3D80 A;  2L28 A;  3IRM A;  3QLR A;  4OSG A;  1J3J A;  4XT4 A;  3FQV A;  3FY9 X;  3FQO A;  4PTJ A;  3DGA A;  4LAE X;  5DFR A;  3FQC A;  3GI2 A;  4KJK A;  4XRB A;  1BOZ A;  4HOG A;  3TQB A;  1ZDR A;  3SR5 X;  2W9H A;  1M79 A;  3FY8 X;  4G95 A;  4HOF A;  3DL5 A;  2BL9 A;  4HA9 A;  1JOL A;  3JWF A;  3Q1H A;  4P3R A;  1RX7 A;  4P66 A;  3SRQ X;  1RX4 A;  3EEK A;  1DRE A;  2QK8 A;  1S3U A;  3S7A A;  3FRA X;  4Q0D A;  3QLS A;  1DIU A;  2CD2 A;  1LUD A;  1VJ3 A;  3NXR A;  3QYO A;  1DF7 A;  2INQ A;  4I1N A;  3S3V A;  3QLZ A;  1M78 A;  4P3Q A;  3JSU A;  1RA3 A;  3EEM A;  3NXY A;  4XT5 A;  5HVE A;  2LF1 A;  3JWM A;  1DG7 A;  1RX5 A;  3F0B X;  3FRD X;  1RB3 A;  2W3A A;  4H96 A;  5ECX A;  7DFR A;  1DYJ A;  4KM0 A;  1CZ3 A;  2OBC A;  3KFY A;  1PD8 A;  1RE7 A;  3CLB A;  3FL9 A;  3VCO A;  1RA8 A;  3HBB A;  2CIG A;  3GHC A;  4Q6A A;  1DHJ A;  1RA1 A;  3IX9 A;  4KD7 A;  4DPD A;  1DHF A;  4PDJ A;  2W3V A;  1DDS A;  4XEC X;  3SA1 A;  4DP3 A;  1RX9 A;  4XT7 A;  4PTH A;  4ELB A;  1TDR A;  3EIG A;  1DLS A;  1DR2 A;  1LY4 A;  3F8Z A;  3UM6 A;  1DIS A;  5ECC A;  3IA4 A;  3I8A X;  3QLY A;  3QL0 A;  1DG8 A;  1MVT A;  3F0S X;  3SRR X;  3DRC A;  4EIL A;  2ZZA A;  4KL9 A;  4QLF A;  1IA4 A;  1IA3 A;  2HXV A;  2D5N A;  4P68 A;  4OR7 A;  3FYW X;  4FGG A;  5CCC A;  1M7A A;  4ELF A;  5HQZ A;  3JWK A;  3K47 A;  3CL9 A;  5U26 A;  1DHI A;  4XT8 A;  5JA3 A;  1AOE A;  3DFR A;  5JG0 X;  3D84 X;  3DL6 A;  4FHB A;  1DYI A;  1AI9 A;  3NXT A;  4KM2 A;  4X5I A;  3I3R A;  3NXV A;  3INV A;  3NXO A;  2HQP A;  3K74 A;  1CD2 A;  4KEB A;  3F0U X;  2DRC A;  4KLX A;  3RG9 A;  1HFP A;  3FYV X;  1RA2 A;  8DFR A;  4PSY A;  3NTZ A;  1IA2 A;  1DRA A;  3FS6 A;  3ZPC A;  1DR5 A;  3JTW A;  3GYF A;  1BZF A;  3NZA X;  3JVX A;  3M08 A;  1J3K A;  2AZN A;  3F0Q X;  5U27 A;  1YHO A;  1OHK A;  4QI9 A;  3TQ9 A;  4ELG A;  4LEK X;  4XE6 X;  4KY4 A;  3SAI A;  1RX1 A;  2W3B A;  1RX6 A;  1RX8 A;  1RB2 A;  5DXV A;  1DAJ A;  3NZD A;  1U71 A;  1RX2 A;  2W9S A;  3QFX A;  3TQ8 A;  1JUV A;  3SRU X;  1U70 A;  3IA5 A;  2ANQ A;  2ITH A;  2W3W A;  1RH3 A;  3SRS X;  3TD8 A;  4NX6 A;  1U72 A;  3NU0 A;  5HF0 X;  1D1G A;  1KLK A;  3SGY A;  3N0H A;  4QLG A;  1DR4 A;  1S3V A;  1S3W A;  3FRB X;  4DDR A;  5HT5 A;  4KFJ A;  2D0K A;  1PDB A;  3GHV A;  4DPH A;  3SRW X;  4M6J A;  4ECK A;  4KBN A;  2DHF A;  3K45 A;  4ELH A;  1MVS A;  1DR6 A;  4M6L A;  4KAK A;  4M7V A;  3R33 A;  2XW7 A;  3QLX A;  1IA1 A;  2C2T A;  4PST A;  3FQF A;  1RA9 A;  3KJR A;  4H95 A;  3IRN A;  3L3R A;  3NZC X;  3DAU A;  1SEJ A;  3EEL A;  3DAT A;  4X5H A;  3SQY X;  4X5J A;  1AO8 A;  3NRR A;  5HI6 A;  2BLB A;  1DDR A;  2ANO A;  2GD9 A;  1LY3 A;  4KY8 A;  4Q0E A;  6DFR A;  4QJC A;  3M09 A;  1DR1 A;  4QHV A;  3SA2 A;  1OHJ A;  4LAH X;  2H2Q A;  1JOM A;  3SH2 A;  4TU5 X;  3NXX A;  4QLE A;  4KJJ A;  5FDA A;  3S9U A;  3UM8 A;  4KJL A;  3OAF A;  3ZPG A;  5E8Q A;  5HVB A;  4X5G A;  4G8Z X;  3NZB X;  1S3Y A;  3F0V X;  3CD2 A;  1DYR A;  3F8Y A;  1RG7 A;  5HF2 X;  1DLR A;  3IRO A;  4IXG X;  3QL3 A;  4NX7 A;  2W3M A;  4KNE A;  3GHW A;  1VDR A;  2OIP A;  2W9T A;  2P4G A;  3KY8 A;  4LAG X;  1DYH A;  1DRH A;  2C2S A;  4HOE A;  5CC9 A;  5HSR A;  2G6V A;  1RD7 A;  5HUI A;  1RF7 A;  2FZH A;  2O7P A;  4X5F A;  3FQ0 A;  4HA7 A;  4DFR A;  2BLC A;  3TQA A;  1RC4 A;  1DRB A;  1DR3 A;  2JYB A;  4EIG A;  3DG8 A;  3OCH A;  3JW5 A;  4QJZ D;  4PSS A;  3UM5 A;  2B3Z A;  4M7U A;  3EX8 A;  3LG4 A;  1DR7 A;  3F91 A;  4GH8 A;  5HPB A;  1HFQ A;  1HFR A;  3QG2 A;  3FRE X;  3RO9 A;  3HJ3 A;  2KGK A;  3NZ6 X;  5HQY A;  4EJ1 A;  1J3I A;  2FZI A;  1QZF A;  3QGT A;  3EEJ A;  4KYA A;  4I13 A;  3FL8 A;  4G3M A;  4H97 A;  5HT4 A;  4RGC A;  4M2X A;  3JWC A;  2BLA A;  1E26 A;  3K2H A;  4Q67 A;  4XT6 A;  2HM9 A;  3FQZ A;  4FGH A;  4ELE A;  3F0X X;  1DG5 A;  4H98 A; 
#chains in the Genus database with same CATH homology
 3KJS A;  3KGY A;  3QLW A;  4M6K A;  2FZJ A;  1KMV A;  2W9G A;  4CD2 A;  3CSE A;  3FRF X;  1DRF A;  3NZ9 X;  1PD9 A;  3E0B A;  5EAJ A;  1KMS A;  3ROA A;  3JW3 A;  3QYL A;  4EIZ A;  5HSU A;  4IXE D;  4IXF X;  1RX3 A;  3D80 A;  2L28 A;  3IRM A;  3QLR A;  4OSG A;  1J3J A;  4XT4 A;  3FQV A;  3FY9 X;  3FQO A;  4PTJ A;  3DGA A;  4LAE X;  5DFR A;  3FQC A;  3GI2 A;  4KJK A;  4XRB A;  1BOZ A;  4HOG A;  3TQB A;  1ZDR A;  3SR5 X;  2W9H A;  1M79 A;  3FY8 X;  4G95 A;  4HOF A;  3DL5 A;  2BL9 A;  4HA9 A;  1JOL A;  3JWF A;  3Q1H A;  4P3R A;  1RX7 A;  4P66 A;  3SRQ X;  1RX4 A;  3EEK A;  1DRE A;  2QK8 A;  1S3U A;  3S7A A;  3FRA X;  4Q0D A;  3QLS A;  1DIU A;  2CD2 A;  1LUD A;  1VJ3 A;  3NXR A;  3QYO A;  1DF7 A;  2INQ A;  4I1N A;  3S3V A;  3QLZ A;  1M78 A;  4P3Q A;  3JSU A;  1RA3 A;  3EEM A;  3NXY A;  4XT5 A;  5HVE A;  2LF1 A;  3JWM A;  1DG7 A;  1RX5 A;  3F0B X;  3FRD X;  1RB3 A;  2W3A A;  4H96 A;  5ECX A;  7DFR A;  1DYJ A;  4KM0 A;  1CZ3 A;  2OBC A;  3KFY A;  1PD8 A;  1RE7 A;  3CLB A;  3FL9 A;  3VCO A;  1RA8 A;  3HBB A;  2CIG A;  3GHC A;  4Q6A A;  1DHJ A;  1RA1 A;  3IX9 A;  4KD7 A;  4DPD A;  1DHF A;  4PDJ A;  2W3V A;  1DDS A;  4XEC X;  3SA1 A;  4DP3 A;  1RX9 A;  4XT7 A;  4PTH A;  4ELB A;  1TDR A;  3EIG A;  1DLS A;  1DR2 A;  1LY4 A;  3F8Z A;  3UM6 A;  1DIS A;  5ECC A;  3IA4 A;  3I8A X;  3QLY A;  3QL0 A;  1DG8 A;  1MVT A;  3F0S X;  3SRR X;  3DRC A;  4EIL A;  2ZZA A;  4KL9 A;  4QLF A;  1IA4 A;  1IA3 A;  2HXV A;  2D5N A;  4P68 A;  4OR7 A;  3FYW X;  4FGG A;  5CCC A;  1M7A A;  4ELF A;  5HQZ A;  3JWK A;  3K47 A;  3CL9 A;  5U26 A;  1DHI A;  4XT8 A;  5JA3 A;  1AOE A;  3DFR A;  5JG0 X;  3D84 X;  3DL6 A;  4FHB A;  1DYI A;  1AI9 A;  3NXT A;  4KM2 A;  4X5I A;  3I3R A;  3NXV A;  3INV A;  3NXO A;  2HQP A;  3K74 A;  1CD2 A;  4KEB A;  3F0U X;  2DRC A;  4KLX A;  3RG9 A;  1HFP A;  3FYV X;  1RA2 A;  8DFR A;  4PSY A;  3NTZ A;  1IA2 A;  1DRA A;  3FS6 A;  3ZPC A;  1DR5 A;  3JTW A;  3GYF A;  1BZF A;  3NZA X;  3JVX A;  3M08 A;  1J3K A;  2AZN A;  3F0Q X;  5U27 A;  1YHO A;  1OHK A;  4QI9 A;  3TQ9 A;  4ELG A;  4LEK X;  4XE6 X;  4KY4 A;  3SAI A;  1RX1 A;  2W3B A;  1RX6 A;  1RX8 A;  1RB2 A;  5DXV A;  1DAJ A;  3NZD A;  1U71 A;  1RX2 A;  2W9S A;  3QFX A;  3TQ8 A;  1JUV A;  3SRU X;  1U70 A;  3IA5 A;  2ANQ A;  2ITH A;  2W3W A;  1RH3 A;  3SRS X;  3TD8 A;  4NX6 A;  1U72 A;  3NU0 A;  5HF0 X;  1D1G A;  1KLK A;  3SGY A;  3N0H A;  4QLG A;  1DR4 A;  1S3V A;  1S3W A;  3FRB X;  4DDR A;  5HT5 A;  4KFJ A;  2D0K A;  1PDB A;  3GHV A;  4DPH A;  3SRW X;  4M6J A;  4ECK A;  4KBN A;  2DHF A;  3K45 A;  4ELH A;  1MVS A;  1DR6 A;  4M6L A;  4KAK A;  4M7V A;  3R33 A;  2XW7 A;  3QLX A;  1IA1 A;  2C2T A;  4PST A;  3FQF A;  1RA9 A;  3KJR A;  4H95 A;  3IRN A;  3L3R A;  3NZC X;  3DAU A;  1SEJ A;  3EEL A;  3DAT A;  4X5H A;  3SQY X;  4X5J A;  1AO8 A;  3NRR A;  5HI6 A;  2BLB A;  1DDR A;  2ANO A;  2GD9 A;  1LY3 A;  4KY8 A;  4Q0E A;  6DFR A;  4QJC A;  3M09 A;  1DR1 A;  4QHV A;  3SA2 A;  1OHJ A;  4LAH X;  2H2Q A;  1JOM A;  3SH2 A;  4TU5 X;  3NXX A;  4QLE A;  4KJJ A;  5FDA A;  3S9U A;  3UM8 A;  4KJL A;  3OAF A;  3ZPG A;  5E8Q A;  5HVB A;  4X5G A;  4G8Z X;  3NZB X;  1S3Y A;  3F0V X;  3CD2 A;  1DYR A;  3F8Y A;  1RG7 A;  5HF2 X;  1DLR A;  3IRO A;  4IXG X;  3QL3 A;  4NX7 A;  2W3M A;  4KNE A;  3GHW A;  1VDR A;  2OIP A;  2W9T A;  2P4G A;  3KY8 A;  4LAG X;  1DYH A;  1DRH A;  2C2S A;  4HOE A;  5CC9 A;  5HSR A;  2G6V A;  1RD7 A;  5HUI A;  1RF7 A;  2FZH A;  2O7P A;  4X5F A;  3FQ0 A;  4HA7 A;  4DFR A;  2BLC A;  3TQA A;  1RC4 A;  1DRB A;  1DR3 A;  2JYB A;  4EIG A;  3DG8 A;  3OCH A;  3JW5 A;  4QJZ D;  4PSS A;  3UM5 A;  2B3Z A;  4M7U A;  3EX8 A;  3LG4 A;  1DR7 A;  3F91 A;  4GH8 A;  5HPB A;  1HFQ A;  1HFR A;  3QG2 A;  3FRE X;  3RO9 A;  3HJ3 A;  2KGK A;  3NZ6 X;  5HQY A;  4EJ1 A;  1J3I A;  2FZI A;  1QZF A;  3QGT A;  3EEJ A;  4KYA A;  4I13 A;  3FL8 A;  4G3M A;  4H97 A;  5HT4 A;  4RGC A;  4M2X A;  3JWC A;  2BLA A;  1E26 A;  3K2H A;  4Q67 A;  4XT6 A;  2HM9 A;  3FQZ A;  4FGH A;  4ELE A;  3F0X X;  1DG5 A;  4H98 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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