1L6EA

Solution structure of the docking and dimerization domain of protein kinase a ii-alpha (riialpha d/d). alternatively called the n-terminal dimerization domain of the regulatory subunit of protein kinase a.
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
46
structure length
46
Chain Sequence
HMGHIQIPPGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords cAMP-dependent protein kinase Type II-alpha regulatory chain
publication title Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIalpha
pubmed doi rcsb
source organism Mus musculus
total genus 11
structure length 46
sequence length 46
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 2002-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 1l6eA00
5HVZA 2DRNA 2IZYA 2KYGA 4F9KA 2H9RA 4RTAA 4ZP3A 3G36A 1L6EA 3IM3A 2EZWA 4RT4A 1R2AA 3IM4A 4RIQA
chains in the Genus database with same CATH superfamily
5HVZA 2DRNA 2IZYA 3RRSA 3S4BA 4F9KA 3RSYA 3QG0A 4ZP3A 3ACSA 3IM3A 2KNGA 1R2AA 3S4AA 2CQTA 2I15A 3S4DA 3G36A 1L6EA 2CBGA 2CQSA 4RIQA 3AFJA 3PMIA 2KYGA 2H9RA 2OUTA 3UFEA 2EZWA 4RT4A 3ACTA 2K9QA 3QDEA 3QFZA 4RTAA 2CB9A 2RQYA 3S4CA 3QFYA 3IM4A 3GWHA
chains in the Genus database with same CATH topology
5HVZA 2DRNA 2IZYA 2KYGA 4F9KA 2H9RA 4RTAA 4ZP3A 3G36A 1L6EA 3IM3A 2EZWA 4RT4A 1R2AA 3IM4A 4RIQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HVZ A;  2DRN A;  2IZY A;  2KYG A;  4F9K A;  2H9R A;  4RTA A;  4ZP3 A;  3G36 A;  1L6E A;  3IM3 A;  2EZW A;  4RT4 A;  1R2A A;  3IM4 A;  4RIQ A; 
#chains in the Genus database with same CATH topology
 5HVZ A;  2DRN A;  2IZY A;  3RRS A;  3S4B A;  4F9K A;  3RSY A;  3QG0 A;  4ZP3 A;  3ACS A;  3IM3 A;  2KNG A;  1R2A A;  3S4A A;  2CQT A;  2I15 A;  3S4D A;  3G36 A;  1L6E A;  2CBG A;  2CQS A;  4RIQ A;  3AFJ A;  3PMI A;  2KYG A;  2H9R A;  2OUT A;  3UFE A;  2EZW A;  4RT4 A;  3ACT A;  2K9Q A;  3QDE A;  3QFZ A;  4RTA A;  2CB9 A;  2RQY A;  3S4C A;  3QFY A;  3IM4 A;  3GWH A; 
#chains in the Genus database with same CATH homology
 5HVZ A;  2DRN A;  2IZY A;  2KYG A;  4F9K A;  2H9R A;  4RTA A;  4ZP3 A;  3G36 A;  1L6E A;  3IM3 A;  2EZW A;  4RT4 A;  1R2A A;  3IM4 A;  4RIQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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