2EZWA

Solution structure of the docking and dimerization domain of the type i alpha regulatory subunit of protein kinase a (rialpha d/d)
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
50
structure length
50
Chain Sequence
SLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFEKLEKEEAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords cAMP-dependent protein kinase type I-alpha regulatory subuni
publication title Related Protein-Protein Interaction Modules Present Drastically Different Surface Topographies Despite A Conserved Helical Platform
pubmed doi rcsb
source organism Bos taurus
total genus 10
structure length 50
sequence length 50
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 2005-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 2ezwA00
1R2AA 5HVZA 3IM4A 4ZP3A 4F9KA 2IZYA 3G36A 2EZWA 3IM3A 2DRNA 2KYGA 4RTAA 4RIQA 2H9RA 4RT4A 1L6EA
chains in the Genus database with same CATH superfamily
5HVZA 4ZP3A 4F9KA 2K9QA 3IM3A 3S4AA 3ACSA 2RQYA 2DRNA 3AFJA 3ACTA 4RTAA 4RIQA 2H9RA 1L6EA 3RRSA 3S4DA 3IM4A 3QFYA 2IZYA 3G36A 2KNGA 3S4CA 2CQSA 3GWHA 2CBGA 2I15A 3QDEA 4RT4A 2CQTA 1R2AA 3PMIA 2CB9A 2EZWA 3UFEA 2KYGA 3S4BA 3QG0A 2OUTA 3QFZA 3RSYA
chains in the Genus database with same CATH topology
1R2AA 5HVZA 3IM4A 4ZP3A 4F9KA 2IZYA 3G36A 2EZWA 3IM3A 2DRNA 2KYGA 4RTAA 4RIQA 2H9RA 4RT4A 1L6EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R2A A;  5HVZ A;  3IM4 A;  4ZP3 A;  4F9K A;  2IZY A;  3G36 A;  2EZW A;  3IM3 A;  2DRN A;  2KYG A;  4RTA A;  4RIQ A;  2H9R A;  4RT4 A;  1L6E A; 
#chains in the Genus database with same CATH topology
 5HVZ A;  4ZP3 A;  4F9K A;  2K9Q A;  3IM3 A;  3S4A A;  3ACS A;  2RQY A;  2DRN A;  3AFJ A;  3ACT A;  4RTA A;  4RIQ A;  2H9R A;  1L6E A;  3RRS A;  3S4D A;  3IM4 A;  3QFY A;  2IZY A;  3G36 A;  2KNG A;  3S4C A;  2CQS A;  3GWH A;  2CBG A;  2I15 A;  3QDE A;  4RT4 A;  2CQT A;  1R2A A;  3PMI A;  2CB9 A;  2EZW A;  3UFE A;  2KYG A;  3S4B A;  3QG0 A;  2OUT A;  3QFZ A;  3RSY A; 
#chains in the Genus database with same CATH homology
 1R2A A;  5HVZ A;  3IM4 A;  4ZP3 A;  4F9K A;  2IZY A;  3G36 A;  2EZW A;  3IM3 A;  2DRN A;  2KYG A;  4RTA A;  4RIQ A;  2H9R A;  4RT4 A;  1L6E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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