1R2AA

The molecular basis for protein kinase a anchoring revealed by solution nmr
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
46
structure length
46
Chain Sequence
HMGHIQIPPGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transferase
molecule keywords PROTEIN (CAMP-DEPENDENT PROTEIN KINASE TYPE II REGULATORY SU
publication title The molecular basis for protein kinase A anchoring revealed by solution NMR.
pubmed doi rcsb
source organism Mus musculus
total genus 12
structure length 46
sequence length 46
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 1998-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 1r2aA00
4RIQA 3IM3A 5HVZA 1R2AA 1L6EA 2EZWA 4ZP3A 2KYGA 2H9RA 4RTAA 2DRNA 3G36A 3IM4A 4F9KA 4RT4A 2IZYA
chains in the Genus database with same CATH superfamily
4RIQA 3QG0A 1L6EA 3AFJA 2KYGA 3ACTA 3S4AA 2H9RA 3G36A 2CB9A 2K9QA 2OUTA 2IZYA 3IM3A 3PMIA 5HVZA 3S4DA 1R2AA 2EZWA 3GWHA 4F9KA 2RQYA 2I15A 3QDEA 2KNGA 4ZP3A 3RSYA 2DRNA 3RRSA 3IM4A 2CBGA 3S4BA 3QFZA 3UFEA 3ACSA 3QFYA 2CQTA 4RTAA 2CQSA 3S4CA 4RT4A
chains in the Genus database with same CATH topology
4RIQA 3IM3A 5HVZA 1R2AA 1L6EA 2EZWA 4ZP3A 2KYGA 2H9RA 4RTAA 2DRNA 3G36A 3IM4A 4F9KA 4RT4A 2IZYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RIQ A;  3IM3 A;  5HVZ A;  1R2A A;  1L6E A;  2EZW A;  4ZP3 A;  2KYG A;  2H9R A;  4RTA A;  2DRN A;  3G36 A;  3IM4 A;  4F9K A;  4RT4 A;  2IZY A; 
#chains in the Genus database with same CATH topology
 4RIQ A;  3QG0 A;  1L6E A;  3AFJ A;  2KYG A;  3ACT A;  3S4A A;  2H9R A;  3G36 A;  2CB9 A;  2K9Q A;  2OUT A;  2IZY A;  3IM3 A;  3PMI A;  5HVZ A;  3S4D A;  1R2A A;  2EZW A;  3GWH A;  4F9K A;  2RQY A;  2I15 A;  3QDE A;  2KNG A;  4ZP3 A;  3RSY A;  2DRN A;  3RRS A;  3IM4 A;  2CBG A;  3S4B A;  3QFZ A;  3UFE A;  3ACS A;  3QFY A;  2CQT A;  4RTA A;  2CQS A;  3S4C A;  4RT4 A; 
#chains in the Genus database with same CATH homology
 4RIQ A;  3IM3 A;  5HVZ A;  1R2A A;  1L6E A;  2EZW A;  4ZP3 A;  2KYG A;  2H9R A;  4RTA A;  2DRN A;  3G36 A;  3IM4 A;  4F9K A;  4RT4 A;  2IZY A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...