2DRNA

Docking and dimerization domain (d/d) of the type ii-alpha regulatory subunity of protein kinase a (pka) in complex with a peptide from an a-kinase anchoring protein
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
46
structure length
46
Chain Sequence
HMGHIQIPPGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords cAMP-dependent protein kinase type II-alpha regulatory subun
publication title A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 13
structure length 46
sequence length 46
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 2006-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 2drnA00
2KYGA 2H9RA 3IM4A 4ZP3A 5HVZA 4RTAA 2IZYA 4F9KA 1L6EA 1R2AA 2DRNA 3G36A 4RIQA 3IM3A 2EZWA 4RT4A
chains in the Genus database with same CATH superfamily
3UFEA 2I15A 2H9RA 3ACTA 5HVZA 3QFYA 2IZYA 2OUTA 4RIQA 3QFZA 2K9QA 2EZWA 2KYGA 2CB9A 3RSYA 2CBGA 3RRSA 4F9KA 2KNGA 3PMIA 3AFJA 3ACSA 3QDEA 3S4CA 3GWHA 2RQYA 3QG0A 1L6EA 2DRNA 3G36A 2CQTA 2CQSA 4RT4A 3S4DA 3S4BA 3IM4A 4ZP3A 4RTAA 3S4AA 1R2AA 3IM3A
chains in the Genus database with same CATH topology
2KYGA 2H9RA 3IM4A 4ZP3A 5HVZA 4RTAA 2IZYA 4F9KA 1L6EA 1R2AA 2DRNA 3G36A 4RIQA 3IM3A 2EZWA 4RT4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KYG A;  2H9R A;  3IM4 A;  4ZP3 A;  5HVZ A;  4RTA A;  2IZY A;  4F9K A;  1L6E A;  1R2A A;  2DRN A;  3G36 A;  4RIQ A;  3IM3 A;  2EZW A;  4RT4 A; 
#chains in the Genus database with same CATH topology
 3UFE A;  2I15 A;  2H9R A;  3ACT A;  5HVZ A;  3QFY A;  2IZY A;  2OUT A;  4RIQ A;  3QFZ A;  2K9Q A;  2EZW A;  2KYG A;  2CB9 A;  3RSY A;  2CBG A;  3RRS A;  4F9K A;  2KNG A;  3PMI A;  3AFJ A;  3ACS A;  3QDE A;  3S4C A;  3GWH A;  2RQY A;  3QG0 A;  1L6E A;  2DRN A;  3G36 A;  2CQT A;  2CQS A;  4RT4 A;  3S4D A;  3S4B A;  3IM4 A;  4ZP3 A;  4RTA A;  3S4A A;  1R2A A;  3IM3 A; 
#chains in the Genus database with same CATH homology
 2KYG A;  2H9R A;  3IM4 A;  4ZP3 A;  5HVZ A;  4RTA A;  2IZY A;  4F9K A;  1L6E A;  1R2A A;  2DRN A;  3G36 A;  4RIQ A;  3IM3 A;  2EZW A;  4RT4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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