1V66A

Solution structure of human p53 binding domain of pias-1
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
65
structure length
65
Chain Sequence
MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
molecule keywords Protein inhibitor of activated STAT protein 1
publication title NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers
pubmed doi rcsb
source organism Homo sapiens
total genus 20
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2003-11-27
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.30 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 SAP domain 1v66A00
2KVEA 2RNOA 2JVWA 1H1JS 1V66A 1JEQA 4BITA 1ZBHA 2KVUA 2KVDA 4UZWA 1JJRA 2RNNA 2KW9A 2WQGA
chains in the Genus database with same CATH superfamily
1A8VA 1KHCA 2RNOA 1E7LA 1GJJA 2ODGC 2HJQA 2KVUA 1A63A 2QNCA 2MPHA 2KW9A 2WQGA 1H9FA 2A8VA 1H9EA 3LLRA 1E7DA 2LD7A 1H1JS 1JEQA 2KVDA 2DK4A 1JJRA 2G80A 1YNSA 1EN7A 1A62A 1ZBHA 5CIUA 1ZS9A 4UZWA 1Y02A 2ODCI 2RNNA 3L0OA 1GL9B 2QNFA 2W51A 2KVEA 3FLGA 2KFVA 2JVWA 1JEIA 1V66A 1GKUB 2LC3A 4BITA 3QKJA
chains in the Genus database with same CATH topology
2KVEA 2RNOA 2JVWA 1H1JS 1V66A 1JEQA 4BITA 1ZBHA 2KVUA 2KVDA 4UZWA 1JJRA 2RNNA 2KW9A 2WQGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KVE A;  2RNO A;  2JVW A;  1H1J S;  1V66 A;  1JEQ A;  4BIT A;  1ZBH A;  2KVU A;  2KVD A;  4UZW A;  1JJR A;  2RNN A;  2KW9 A;  2WQG A; 
#chains in the Genus database with same CATH topology
 1A8V A;  1KHC A;  2RNO A;  1E7L A;  1GJJ A;  2ODG C;  2HJQ A;  2KVU A;  1A63 A;  2QNC A;  2MPH A;  2KW9 A;  2WQG A;  1H9F A;  2A8V A;  1H9E A;  3LLR A;  1E7D A;  2LD7 A;  1H1J S;  1JEQ A;  2KVD A;  2DK4 A;  1JJR A;  2G80 A;  1YNS A;  1EN7 A;  1A62 A;  1ZBH A;  5CIU A;  1ZS9 A;  4UZW A;  1Y02 A;  2ODC I;  2RNN A;  3L0O A;  1GL9 B;  2QNF A;  2W51 A;  2KVE A;  3FLG A;  2KFV A;  2JVW A;  1JEI A;  1V66 A;  1GKU B;  2LC3 A;  4BIT A;  3QKJ A; 
#chains in the Genus database with same CATH homology
 2KVE A;  2RNO A;  2JVW A;  1H1J S;  1V66 A;  1JEQ A;  4BIT A;  1ZBH A;  2KVU A;  2KVD A;  4UZW A;  1JJR A;  2RNN A;  2KW9 A;  2WQG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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