2KVEA

C-terminal domain of mesencephalic astrocyte-derived neurotrophic factor (manf)
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
MGKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASARTDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hormone
molecule keywords Mesencephalic astrocyte-derived neurotrophic factor
publication title Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
pubmed doi rcsb
source organism Homo sapiens
total genus 11
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2010-03-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.30 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 SAP domain 2kveA00
2KVDA 1V66A 2JVWA 4UZWA 4BITA 1H1JS 2RNOA 2KW9A 2WQGA 1JEQA 2KVUA 1ZBHA 2KVEA 1JJRA 2RNNA
chains in the Genus database with same CATH superfamily
2KVDA 1V66A 4BITA 1YNSA 2HJQA 2ODCI 1H1JS 1JEQA 2KVUA 2G80A 5CIUA 2LC3A 2MPHA 1Y02A 1ZS9A 1JEIA 1A62A 2A8VA 1H9FA 1GL9B 2JVWA 2LD7A 1E7DA 1KHCA 3L0OA 1JJRA 2DK4A 1A8VA 1H9EA 4UZWA 2RNOA 2WQGA 1E7LA 2QNFA 2KVEA 3LLRA 2RNNA 3FLGA 2W51A 1EN7A 1GJJA 2QNCA 1A63A 2ODGC 3QKJA 2KW9A 1ZBHA 1GKUB 2KFVA
chains in the Genus database with same CATH topology
2KVDA 1V66A 2JVWA 4UZWA 4BITA 1H1JS 2RNOA 2KW9A 2WQGA 1JEQA 2KVUA 1ZBHA 2KVEA 1JJRA 2RNNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KVD A;  1V66 A;  2JVW A;  4UZW A;  4BIT A;  1H1J S;  2RNO A;  2KW9 A;  2WQG A;  1JEQ A;  2KVU A;  1ZBH A;  2KVE A;  1JJR A;  2RNN A; 
#chains in the Genus database with same CATH topology
 2KVD A;  1V66 A;  4BIT A;  1YNS A;  2HJQ A;  2ODC I;  1H1J S;  1JEQ A;  2KVU A;  2G80 A;  5CIU A;  2LC3 A;  2MPH A;  1Y02 A;  1ZS9 A;  1JEI A;  1A62 A;  2A8V A;  1H9F A;  1GL9 B;  2JVW A;  2LD7 A;  1E7D A;  1KHC A;  3L0O A;  1JJR A;  2DK4 A;  1A8V A;  1H9E A;  4UZW A;  2RNO A;  2WQG A;  1E7L A;  2QNF A;  2KVE A;  3LLR A;  2RNN A;  3FLG A;  2W51 A;  1EN7 A;  1GJJ A;  2QNC A;  1A63 A;  2ODG C;  3QKJ A;  2KW9 A;  1ZBH A;  1GKU B;  2KFV A; 
#chains in the Genus database with same CATH homology
 2KVD A;  1V66 A;  2JVW A;  4UZW A;  4BIT A;  1H1J S;  2RNO A;  2KW9 A;  2WQG A;  1JEQ A;  2KVU A;  1ZBH A;  2KVE A;  1JJR A;  2RNN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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