2WZKA

Structure of the cul5 n-terminal domain at 2.05a resolution.
Total Genus 152
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
152
sequence length
377
structure length
369
Chain Sequence
SLQFEDKWDFMHPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGSSKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEVTLLGKMEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYREQLDTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKAENL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
molecule keywords CULLIN-5
publication title Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases
pubmed doi rcsb
source organism Mus musculus
total genus 152
structure length 369
sequence length 377
ec nomenclature
pdb deposition date 2009-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA03
4HXIB 4WQOD 1LDJA 1U6GA 4P5OA 4N9F3 3RTRA 4AP2B 4F52A 4APFB 4EOZB 3DPLC 2WZKA 4A64A 1LDKA 4JGHD 3DQVC 1LDKB
chains in the Genus database with same CATH superfamily
4YFSA 3BQIA 1LDJA 4P5OA 4NUUA 4F52A 4APFB 2Y8DA 3DQVC 5F3JA 1LDKB 4HXIB 2WAUA 3CPZA 4N9F3 3RRCA 4EOZB 1LDKA 3BQKA 4WQOD 1U6GA 2PFVA 3DPLC 2WZKA 4NUVA 3CMLA 4JGHD 2B1EA 4AP2B 3RTRA 2XU0A 3BQLA 4A64A
chains in the Genus database with same CATH topology
4HXIB 4WQOD 1LDJA 1U6GA 4P5OA 4N9F3 3RTRA 4AP2B 4F52A 4APFB 4EOZB 3DPLC 2WZKA 4A64A 1LDKA 4JGHD 3DQVC 1LDKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HXI B;  4WQO D;  1LDJ A;  1U6G A;  4P5O A;  4N9F 3;  3RTR A;  4AP2 B;  4F52 A;  4APF B;  4EOZ B;  3DPL C;  2WZK A;  4A64 A;  1LDK A;  4JGH D;  3DQV C;  1LDK B; 
#chains in the Genus database with same CATH topology
 4YFS A;  3BQI A;  1LDJ A;  4P5O A;  4NUU A;  4F52 A;  4APF B;  2Y8D A;  3DQV C;  5F3J A;  1LDK B;  4HXI B;  2WAU A;  3CPZ A;  4N9F 3;  3RRC A;  4EOZ B;  1LDK A;  3BQK A;  4WQO D;  1U6G A;  2PFV A;  3DPL C;  2WZK A;  4NUV A;  3CML A;  4JGH D;  2B1E A;  4AP2 B;  3RTR A;  2XU0 A;  3BQL A;  4A64 A; 
#chains in the Genus database with same CATH homology
 4HXI B;  4WQO D;  1LDJ A;  1U6G A;  4P5O A;  4N9F 3;  3RTR A;  4AP2 B;  4F52 A;  4APF B;  4EOZ B;  3DPL C;  2WZK A;  4A64 A;  1LDK A;  4JGH D;  3DQV C;  1LDK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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