4WQOD

Structure of vhl-elob-eloc-cul2
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
159
structure length
141
Chain Sequence
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNPLMEIGELALDMWRKLMVEPLQAIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
molecule keywords Von Hippel-Lindau disease tumor suppressor
publication title Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex.
pubmed doi rcsb
source organism Homo sapiens
total genus 52
structure length 141
sequence length 159
ec nomenclature
pdb deposition date 2014-10-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4wqoD00
4A64A 4P5OA 4JGHD 4F52A 4HXIB 3RTRA 4N9F3 3DPLC 2WZKA 4AP2B 3DQVC 4EOZB 4APFB 1LDJA 1LDKB 1U6GA 4WQOD 1LDKA
chains in the Genus database with same CATH superfamily
2Y8DA 4A64A 3BQKA 4F52A 3RTRA 3CPZA 4N9F3 2WAUA 1LDKA 4AP2B 1LDKB 1U6GA 4EOZB 4P5OA 2PFVA 4NUUA 2XU0A 4YFSA 3CMLA 2B1EA 5F3JA 4NUVA 4HXIB 3BQIA 4APFB 1LDJA 4WQOD 3BQLA 4JGHD 3DPLC 2WZKA 3RRCA 3DQVC
chains in the Genus database with same CATH topology
4A64A 4P5OA 4JGHD 4F52A 4HXIB 3RTRA 4N9F3 3DPLC 2WZKA 4AP2B 3DQVC 4EOZB 4APFB 1LDJA 1LDKB 1U6GA 4WQOD 1LDKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A64 A;  4P5O A;  4JGH D;  4F52 A;  4HXI B;  3RTR A;  4N9F 3;  3DPL C;  2WZK A;  4AP2 B;  3DQV C;  4EOZ B;  4APF B;  1LDJ A;  1LDK B;  1U6G A;  4WQO D;  1LDK A; 
#chains in the Genus database with same CATH topology
 2Y8D A;  4A64 A;  3BQK A;  4F52 A;  3RTR A;  3CPZ A;  4N9F 3;  2WAU A;  1LDK A;  4AP2 B;  1LDK B;  1U6G A;  4EOZ B;  4P5O A;  2PFV A;  4NUU A;  2XU0 A;  4YFS A;  3CML A;  2B1E A;  5F3J A;  4NUV A;  4HXI B;  3BQI A;  4APF B;  1LDJ A;  4WQO D;  3BQL A;  4JGH D;  3DPL C;  2WZK A;  3RRC A;  3DQV C; 
#chains in the Genus database with same CATH homology
 4A64 A;  4P5O A;  4JGH D;  4F52 A;  4HXI B;  3RTR A;  4N9F 3;  3DPL C;  2WZK A;  4AP2 B;  3DQV C;  4EOZ B;  4APF B;  1LDJ A;  1LDK B;  1U6G A;  4WQO D;  1LDK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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