4HXIB

Crystal structure of klhl3/cul3 complex
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
354
structure length
346
Chain Sequence
DEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMRTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEDYRQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
molecule keywords Kelch-like protein 3
publication title Structural and Functional Characterization of KLHL3/Cul3 complex and implications of FHHt mutations in Cul3 binding
rcsb
source organism Homo sapiens
total genus 139
structure length 346
sequence length 354
ec nomenclature
pdb deposition date 2012-11-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4hxiB01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4hxiB02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4hxiB03
4HXIB 1U6GA 4APFB 3DQVC 4JGHD 2WZKA 1LDJA 4AP2B 4EOZB 4WQOD 3DPLC 1LDKB 4N9F3 1LDKA 4P5OA 4F52A 4A64A 3RTRA
chains in the Genus database with same CATH superfamily
3BQLA 3BQKA 4JGHD 1LDJA 3BQIA 4EOZB 5F3JA 4WQOD 4P5OA 3CMLA 4NUVA 4F52A 4A64A 3DQVC 4YFSA 3RRCA 3DPLC 4N9F3 1LDKA 2WAUA 3RTRA 1U6GA 2Y8DA 2WZKA 4AP2B 4NUUA 4HXIB 4APFB 2XU0A 2PFVA 3CPZA 1LDKB 2B1EA
chains in the Genus database with same CATH topology
4HXIB 1U6GA 4APFB 3DQVC 4JGHD 2WZKA 1LDJA 4AP2B 4EOZB 4WQOD 3DPLC 1LDKB 4N9F3 1LDKA 4P5OA 4F52A 4A64A 3RTRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HXI B;  1U6G A;  4APF B;  3DQV C;  4JGH D;  2WZK A;  1LDJ A;  4AP2 B;  4EOZ B;  4WQO D;  3DPL C;  1LDK B;  4N9F 3;  1LDK A;  4P5O A;  4F52 A;  4A64 A;  3RTR A; 
#chains in the Genus database with same CATH topology
 3BQL A;  3BQK A;  4JGH D;  1LDJ A;  3BQI A;  4EOZ B;  5F3J A;  4WQO D;  4P5O A;  3CML A;  4NUV A;  4F52 A;  4A64 A;  3DQV C;  4YFS A;  3RRC A;  3DPL C;  4N9F 3;  1LDK A;  2WAU A;  3RTR A;  1U6G A;  2Y8D A;  2WZK A;  4AP2 B;  4NUU A;  4HXI B;  4APF B;  2XU0 A;  2PFV A;  3CPZ A;  1LDK B;  2B1E A; 
#chains in the Genus database with same CATH homology
 4HXI B;  1U6G A;  4APF B;  3DQV C;  4JGH D;  2WZK A;  1LDJ A;  4AP2 B;  4EOZ B;  4WQO D;  3DPL C;  1LDK B;  4N9F 3;  1LDK A;  4P5O A;  4F52 A;  4A64 A;  3RTR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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