2XU0A

Crystal structure of the nts-dbl1(alpha-1) domain of the plasmodium falciparum membrane protein 1 (pfemp1) from the varo strain.
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
sequence length
476
structure length
447
Chain Sequence
SPTLSESHKSARNVLENIGIKIYNQEIKKKNPYEQQLKGTLDGNSCNLDHLFGRKPCYGREQNRFDENAEAYCNSDKIRGNENNANGAACAPPRRRHICDQNLEFLDNKNTNTAHDLLGNVLVTAKYEGNYIVNDHPDKNSNGNKAGICTSLARSFADIGDIVRGRDMFLPNKDDKVQKGLQVVFKKIYKSLTPEARKHYAHGDGSGNYAKLREDWWTINREQIWKALTCSAPYYADYFRKGSDGTLHFSSHGKCGHNEGAPPTYLDYVPQFLRWFEEWSEEFCRIKKIKIDKVKKECRDEQNKKYCSGDGHDCTQTNLAHNQIFVDLDCPRCQDQCIKYNEWIVKKLEEFYKQNLKYSMEIQKWKKTKNNYYDKEFYENLDKKSYSTIDKFLNLLNNGKHCHDNKDEKNKIDFNKPIKTFSISEYCKTCPLYGVTCTNRGICIHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Membrane protein
molecule keywords ERYTHROCYTE MEMBRANE PROTEIN 1
publication title Structure of a Plasmodium Falciparum Pfemp1 Rosetting Domain Reveals a Role for the N-Terminal Segment in Heparin-Mediated Rosette Inhibition.
pubmed doi rcsb
source organism Plasmodium falciparum palo alto/uganda
total genus 169
structure length 447
sequence length 476
ec nomenclature
pdb deposition date 2010-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05424 Duffy_binding Duffy binding domain
A PF15447 NTS N-terminal segments of PfEMP1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.20 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like 5 helical Cullin repeat like 2xu0A00
3CPZA 3BQIA 4NUUA 4YFSA 3BQLA 3RRCA 4NUVA 2WAUA 2Y8DA 5F3JA 3CMLA 2XU0A 3BQKA
chains in the Genus database with same CATH superfamily
1LDKB 1U6GA 3BQIA 4JGHD 4APFB 2Y8DA 3CMLA 4EOZB 4NUUA 4YFSA 2PFVA 3RRCA 4NUVA 4AP2B 3DPLC 3BQLA 2WZKA 2WAUA 2B1EA 5F3JA 1LDJA 4HXIB 4WQOD 3BQKA 1LDKA 3CPZA 4N9F3 4F52A 3DQVC 4A64A 4P5OA 2XU0A 3RTRA
chains in the Genus database with same CATH topology
3CPZA 3BQIA 2Y8DA 4NUUA 4YFSA 3BQLA 2PFVA 3RRCA 4NUVA 2WAUA 2B1EA 5F3JA 3CMLA 2XU0A 3BQKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CPZ A;  3BQI A;  4NUU A;  4YFS A;  3BQL A;  3RRC A;  4NUV A;  2WAU A;  2Y8D A;  5F3J A;  3CML A;  2XU0 A;  3BQK A; 
#chains in the Genus database with same CATH topology
 1LDK B;  1U6G A;  3BQI A;  4JGH D;  4APF B;  2Y8D A;  3CML A;  4EOZ B;  4NUU A;  4YFS A;  2PFV A;  3RRC A;  4NUV A;  4AP2 B;  3DPL C;  3BQL A;  2WZK A;  2WAU A;  2B1E A;  5F3J A;  1LDJ A;  4HXI B;  4WQO D;  3BQK A;  1LDK A;  3CPZ A;  4N9F 3;  4F52 A;  3DQV C;  4A64 A;  4P5O A;  2XU0 A;  3RTR A; 
#chains in the Genus database with same CATH homology
 3CPZ A;  3BQI A;  2Y8D A;  4NUU A;  4YFS A;  3BQL A;  2PFV A;  3RRC A;  4NUV A;  2WAU A;  2B1E A;  5F3J A;  3CML A;  2XU0 A;  3BQK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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