4JGHD

Structure of the socs2-elongin bc complex bound to an n-terminal fragment of cullin5
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
378
structure length
368
Chain Sequence
KGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYREQLDTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
molecule keywords Suppressor of cytokine signaling 2
publication title Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes.
pubmed doi rcsb
source organism Homo sapiens
total genus 135
structure length 368
sequence length 378
ec nomenclature
pdb deposition date 2013-03-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4jghD01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4jghD02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4jghD03
4EOZB 4N9F3 1LDKB 3RTRA 4HXIB 4WQOD 4F52A 3DPLC 4APFB 1LDKA 4P5OA 4JGHD 2WZKA 1LDJA 4AP2B 1U6GA 4A64A 3DQVC
chains in the Genus database with same CATH superfamily
5F3JA 4YFSA 4WQOD 4P5OA 3BQLA 3CMLA 1U6GA 4A64A 3BQIA 4N9F3 4NUVA 3RTRA 4APFB 2WZKA 2Y8DA 4EOZB 4NUUA 4F52A 3DPLC 2WAUA 1LDKA 3BQKA 2XU0A 2B1EA 3RRCA 3CPZA 1LDKB 4HXIB 4AP2B 4JGHD 1LDJA 2PFVA 3DQVC
chains in the Genus database with same CATH topology
4EOZB 4N9F3 1LDKB 3RTRA 4HXIB 4WQOD 4F52A 3DPLC 4APFB 1LDKA 4P5OA 4JGHD 2WZKA 1LDJA 4AP2B 1U6GA 4A64A 3DQVC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EOZ B;  4N9F 3;  1LDK B;  3RTR A;  4HXI B;  4WQO D;  4F52 A;  3DPL C;  4APF B;  1LDK A;  4P5O A;  4JGH D;  2WZK A;  1LDJ A;  4AP2 B;  1U6G A;  4A64 A;  3DQV C; 
#chains in the Genus database with same CATH topology
 5F3J A;  4YFS A;  4WQO D;  4P5O A;  3BQL A;  3CML A;  1U6G A;  4A64 A;  3BQI A;  4N9F 3;  4NUV A;  3RTR A;  4APF B;  2WZK A;  2Y8D A;  4EOZ B;  4NUU A;  4F52 A;  3DPL C;  2WAU A;  1LDK A;  3BQK A;  2XU0 A;  2B1E A;  3RRC A;  3CPZ A;  1LDK B;  4HXI B;  4AP2 B;  4JGH D;  1LDJ A;  2PFV A;  3DQV C; 
#chains in the Genus database with same CATH homology
 4EOZ B;  4N9F 3;  1LDK B;  3RTR A;  4HXI B;  4WQO D;  4F52 A;  3DPL C;  4APF B;  1LDK A;  4P5O A;  4JGH D;  2WZK A;  1LDJ A;  4AP2 B;  1U6G A;  4A64 A;  3DQV C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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