3PVWG

Bovine grk2 in complex with gbetagamma subunits and a selective kinase inhibitor (cmpd103a)
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
60
structure length
60
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/signaling protein/inhibitor
molecule keywords Beta-adrenergic receptor kinase 1
publication title Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.
pubmed doi rcsb
source organism Bos taurus
total genus 12
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2010-12-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 3pvwG00
5HE2G 3KRXG 5TDHG 1TBGE 1XHMB 1B9XB 1GOTG 1GG2G 4KFMG 5KDOG 1A0RG 3SN6G 5HE3G 1OMWG 1GP2G 5HE1G 3PVWG 4PNKG 3PVUG 1B9YB 5HE0G 4MK0G 2PBIA 3AH8G 3KRWG 3CIKG 3V5WG 2TRCG 2BCJG 3PSCG
chains in the Genus database with same CATH superfamily
5HE2G 3KRXG 5TDHG 1TBGE 1XHMB 1B9XB 1GOTG 1GG2G 4KFMG 5KDOG 1A0RG 3SN6G 5HE3G 1OMWG 1GP2G 5HE1G 3PVWG 4PNKG 3PVUG 1B9YB 5HE0G 4MK0G 2PBIA 3AH8G 3KRWG 1HFES 1IOJA 3CIKG 3V5WG 2TRCG 2BCJG 3PSCG
chains in the Genus database with same CATH topology
5HE2G 3KRXG 5TDHG 1TBGE 1XHMB 1B9XB 1GOTG 1GG2G 4KFMG 5KDOG 1A0RG 3SN6G 5HE3G 1OMWG 1GP2G 5HE1G 3PVWG 4PNKG 3PVUG 1B9YB 5HE0G 4MK0G 2PBIA 3AH8G 3KRWG 3CIKG 3V5WG 2TRCG 2BCJG 3PSCG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HE2 G;  3KRX G;  5TDH G;  1TBG E;  1XHM B;  1B9X B;  1GOT G;  1GG2 G;  4KFM G;  5KDO G;  1A0R G;  3SN6 G;  5HE3 G;  1OMW G;  1GP2 G;  5HE1 G;  3PVW G;  4PNK G;  3PVU G;  1B9Y B;  5HE0 G;  4MK0 G;  2PBI A;  3AH8 G;  3KRW G;  3CIK G;  3V5W G;  2TRC G;  2BCJ G;  3PSC G; 
#chains in the Genus database with same CATH topology
 5HE2 G;  3KRX G;  5TDH G;  1TBG E;  1XHM B;  1B9X B;  1GOT G;  1GG2 G;  4KFM G;  5KDO G;  1A0R G;  3SN6 G;  5HE3 G;  1OMW G;  1GP2 G;  5HE1 G;  3PVW G;  4PNK G;  3PVU G;  1B9Y B;  5HE0 G;  4MK0 G;  2PBI A;  3AH8 G;  3KRW G;  1HFE S;  1IOJ A;  3CIK G;  3V5W G;  2TRC G;  2BCJ G;  3PSC G; 
#chains in the Genus database with same CATH homology
 5HE2 G;  3KRX G;  5TDH G;  1TBG E;  1XHM B;  1B9X B;  1GOT G;  1GG2 G;  4KFM G;  5KDO G;  1A0R G;  3SN6 G;  5HE3 G;  1OMW G;  1GP2 G;  5HE1 G;  3PVW G;  4PNK G;  3PVU G;  1B9Y B;  5HE0 G;  4MK0 G;  2PBI A;  3AH8 G;  3KRW G;  3CIK G;  3V5W G;  2TRC G;  2BCJ G;  3PSC G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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