5TDHG

The crystal structure of the dominant negative mutant g protein alpha(i)-1-beta-1-gamma-2 g203a/a326s
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
55
structure length
55
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords Guanine nucleotide-binding protein G(i) subunit alpha-1
publication title The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer
pubmed doi rcsb
source organism Homo sapiens
total genus 14
structure length 55
sequence length 55
chains with identical sequence K
ec nomenclature
pdb deposition date 2016-09-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 5tdhG00
3V5WG 2PBIA 1TBGE 4KFMG 3PVWG 1GG2G 5HE3G 3CIKG 3KRXG 3SN6G 1GOTG 4MK0G 4PNKG 1B9XB 3KRWG 2BCJG 3PVUG 1OMWG 1B9YB 5HE0G 5KDOG 1XHMB 1A0RG 1GP2G 3AH8G 5HE1G 3PSCG 5TDHG 5HE2G 2TRCG
chains in the Genus database with same CATH superfamily
3V5WG 2PBIA 1TBGE 4KFMG 3PVWG 1GG2G 5HE3G 3CIKG 3KRXG 3SN6G 1GOTG 4MK0G 4PNKG 1B9XB 3KRWG 2BCJG 3PVUG 1OMWG 1B9YB 1HFES 5HE0G 5KDOG 1XHMB 1A0RG 1GP2G 3AH8G 5HE1G 3PSCG 5TDHG 1IOJA 5HE2G 2TRCG
chains in the Genus database with same CATH topology
3V5WG 2PBIA 1TBGE 4KFMG 3PVWG 1GG2G 5HE3G 3CIKG 3KRXG 3SN6G 1GOTG 4MK0G 4PNKG 1B9XB 3KRWG 2BCJG 3PVUG 1OMWG 1B9YB 5HE0G 5KDOG 1XHMB 1A0RG 1GP2G 3AH8G 5HE1G 3PSCG 5TDHG 5HE2G 2TRCG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V5W G;  2PBI A;  1TBG E;  4KFM G;  3PVW G;  1GG2 G;  5HE3 G;  3CIK G;  3KRX G;  3SN6 G;  1GOT G;  4MK0 G;  4PNK G;  1B9X B;  3KRW G;  2BCJ G;  3PVU G;  1OMW G;  1B9Y B;  5HE0 G;  5KDO G;  1XHM B;  1A0R G;  1GP2 G;  3AH8 G;  5HE1 G;  3PSC G;  5TDH G;  5HE2 G;  2TRC G; 
#chains in the Genus database with same CATH topology
 3V5W G;  2PBI A;  1TBG E;  4KFM G;  3PVW G;  1GG2 G;  5HE3 G;  3CIK G;  3KRX G;  3SN6 G;  1GOT G;  4MK0 G;  4PNK G;  1B9X B;  3KRW G;  2BCJ G;  3PVU G;  1OMW G;  1B9Y B;  1HFE S;  5HE0 G;  5KDO G;  1XHM B;  1A0R G;  1GP2 G;  3AH8 G;  5HE1 G;  3PSC G;  5TDH G;  1IOJ A;  5HE2 G;  2TRC G; 
#chains in the Genus database with same CATH homology
 3V5W G;  2PBI A;  1TBG E;  4KFM G;  3PVW G;  1GG2 G;  5HE3 G;  3CIK G;  3KRX G;  3SN6 G;  1GOT G;  4MK0 G;  4PNK G;  1B9X B;  3KRW G;  2BCJ G;  3PVU G;  1OMW G;  1B9Y B;  5HE0 G;  5KDO G;  1XHM B;  1A0R G;  1GP2 G;  3AH8 G;  5HE1 G;  3PSC G;  5TDH G;  5HE2 G;  2TRC G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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