96
|
265
|
4rx5A |
Bruton's tyrosine kinase (btk) with pyridazinone compound 23 |
91
|
290
|
4f08A |
Discovery and optimization of c-2 methyl imidazo-pyrrolopyridines as potent and orally bioavailable jak1 inhibitors with selectivity over jak2 |
82
|
287
|
4hviA |
Jak3 kinase domain in complex with 2-cyclopropyl-5h-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((r)-1-methyl-2-oxo-2-piperidin-1-yl-ethyl)-amide |
28
|
108
|
4f5bA |
Triple mutant src sh2 domain bound to phosphotyrosine |
29
|
108
|
4f59A |
Triple mutant src sh2 domain |
84
|
273
|
4f4pA |
Syk in complex with ligand lasw836 |
28
|
108
|
4f5aA |
Triple mutant src sh2 domain bound to phosphate ion |
78
|
275
|
4ewhA |
Co-crystal structure of ack1 with inhibitor |
83
|
287
|
4hvdA |
Jak3 kinase domain in complex with 2-cyclopropyl-5h-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((s)-1,2,2-trimethyl-propyl)-amide |
91
|
290
|
4f09A |
Discovery and optimization of c-2 methyl imidazo-pyrrolopyridines as potent and orally bioavailable jak1 inhibitors with selectivity over jak2 |
88
|
289
|
4hvhA |
Jak3 kinase domain in complex with 2-cyclopropyl-5h-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((r)-2-hydroxy-1,2-dimethyl-propyl |
96
|
298
|
4e6qA |
Jak2 kinase (jh1 domain) triple mutant in complex with compound 12 |
101
|
293
|
4e6dA |
Jak2 kinase (jh1 domain) triple mutant in complex with compound 7 |
86
|
297
|
4ehzA |
The jak1 kinase domain in complex with inhibitor |
88
|
277
|
4ebvA |
Structure of focal adhesion kinase catalytic domain in complex with novel allosteric inhibitor |
92
|
290
|
4e4lA |
Jak1 kinase (jh1 domain) in complex with compound 30 |
87
|
291
|
4e1zA |
Structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor |
24
|
101
|
4eihA |
Crystal structure of arg sh2 domain |
88
|
290
|
4e20A |
Structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor |
107
|
377
|
4e93A |
Crystal structure of human feline sarcoma viral oncogene homologue (v-fes)in complex with tae684 |
98
|
348
|
4ekuA |
Crystal structure of ferm domain of proline-rich tyrosine kinase 2 |
93
|
298
|
4e4mA |
Jak2 kinase (jh1 domain) in complex with compound 30 |
160
|
403
|
4dylA |
F-bar domain of human fes tyrosine kinase |
13
|
58
|
4eikA |
Crystal structure of the human fyn sh3 domain in complex with the synthetic peptide vsl12 |
91
|
302
|
4e5wA |
Jak1 kinase (jh1 domain) in complex with compound 26 |
84
|
302
|
4ei4A |
Jak1 kinase (jh1 domain) in complex with compound 20 |
89
|
302
|
4e4nA |
Jak1 kinase (jh1 domain) in complex with compound 49 |
81
|
276
|
4ebwA |
Structure of focal adhesion kinase catalytic domain in complex with novel allosteric inhibitor |
98
|
334
|
4d2vA |
Structure of melk in complex with inhibitors |
86
|
272
|
4d5kA |
Focal adhesion kinase catalytic domain |
103
|
292
|
4d0wA |
Pyrrole-3-carboxamides as potent and selective jak2 inhibitors |
94
|
333
|
4d2tA |
Structure of melk in complex with inhibitors |
76
|
265
|
4csvA |
Tyrosine kinase as - a common ancestor of src and abl bound to gleevec |
12
|
57
|
4d8dA |
Crystal structure of hiv-1 nef fyn-sh3 r96w variant |
103
|
333
|
4d2wA |
Structure of melk in complex with inhibitors |
79
|
272
|
4d5hA |
Focal adhesion kinase catalytic domain |
98
|
293
|
4d0xA |
Pyrrole-3-carboxamides as potent and selective jak2 inhibitors |
81
|
272
|
4d4yA |
Focal adhesion kinase catalytic domain |
81
|
273
|
4d58A |
Focal adhesion kinase catalytic domain in complex with bis-anilino pyrimidine inhibitor |
94
|
289
|
4d1sA |
Pyrrole-3-carboxamides as potent and selective jak2 inhibitors |
103
|
330
|
4cqgA |
The crystal structure of mpk38 in complex with otssp167, an orally- administrative melk selective inhibitor |
82
|
278
|
4dggA |
C-src kinase domain in complex with rm-1-176 |
82
|
273
|
4d55A |
Focal adhesion kinase catalytic domain |
83
|
272
|
4d4rA |
Focal adhesion kinase catalytic domain |
79
|
272
|
4d4sA |
Focal adhesion kinase catalytic domain |
83
|
274
|
4dfnA |
Crystal structure of spleen tyrosine kinase complexed with an adamantylpyrazine inhibitor |
87
|
274
|
4dflA |
Crystal structure of spleen tyrosine kinase complexed with a sulfonamidopyrazine piperidine inhibitor |
82
|
272
|
4d4vA |
Focal adhesion kinase catalytic domain |
95
|
333
|
4d2pA |
Structure of melk in complex with inhibitors |
95
|
330
|
4cyeA |
Crystal structure of avian fak ferm domain fak31-405 at 3.2a |