|
11
|
61
|
4rtxA |
Crystal structure of the src tyrosine kinase sh3 domain t96g/q128r mutant |
|
13
|
60
|
4qt7A |
Crystal structure of the c-src sh3 domain in complex with a peptide from the hepatitis c virus ns5a-protein |
|
90
|
285
|
4rioA |
Crystal structure of jak3 kinase domain in complex with a pyrrolopyridazine carboxamide inhibitor |
|
55
|
132
|
4r32A |
Crystal structure analysis of pyk2 and paxillin ld motifs |
|
13
|
57
|
4rtwA |
Crystal structure of the c-src-sh3 domain e93v/q128r mutant in complex with the high affinity peptide app12 |
|
83
|
287
|
4qpsA |
Crystal structure of jak3 complexed to n-[3-(6-phenylamino-pyrazin-2-yl)-3h-benzoimidazol-5-yl]-acrylamide |
|
79
|
273
|
4q9sA |
Crystal structure of human focal adhesion kinase (fak) bound to compound1 (3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1h)-one) |
|
66
|
264
|
4ppcA |
Itk kinase domain with compound 27 (n-{1-[(1r)-3-(dimethylamino)-1-phenylpropyl]-1h-pyrazol-4-yl}-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide) |
|
88
|
273
|
4px6A |
Syk catalytic domain in complex with a potent pyridopyrimidinone inhibitor |
|
75
|
265
|
4qd6A |
Itk kinase domain in complex with inhibitor compound |
|
76
|
264
|
4pp9A |
Itk kinase domain with compound 1 (n-[1-(3-cyanobenzyl)-1h-pyrazol-4-yl]-2h-indazole-3-carboxamide) |
|
87
|
275
|
4pv0A |
Crystal structure of spleen tyrosine kinase (syk) in complex with an imidazopyrazine inhibitor |
|
159
|
599
|
4oliA |
The pseudokinase/kinase protein from jak-family member tyk2 |
|
93
|
290
|
4py1A |
Crystal structure of tyk2 in complex with compound 15, 6-((2,5-dimethoxyphenyl)thio)-3-(1-methyl-1h-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazine |
|
138
|
541
|
4po6A |
Crystal structure of the human tyk2 ferm and sh2 domains with an ifnar1 intracellular peptide |
|
89
|
290
|
4p7eA |
Triazolopyridine compounds as selective jak1 inhibitors: from hit identification to glpg0634 |
|
69
|
264
|
4ppaA |
Itk kinase domain with compound 11 (n-[1-(3-cyanobenzyl)-1h-pyrazol-4-yl]-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide) |
|
84
|
259
|
4pqnA |
Itk kinase domain with compound gne-9822 |
|
13
|
56
|
4orzA |
Hiv-1 nef protein in complex with single domain antibody sdab19 and an engineered hck sh3 domain |
|
83
|
271
|
4puzA |
Crystal structure of spleen tyrosine kinase (syk) in complex with gs-9973 |
|
67
|
264
|
4ppbA |
Itk kinase domain with compound 28 (n-{1-[(1s)-3-(dimethylamino)-1-phenylpropyl]-1h-pyrazol-4-yl}-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide) |
|
94
|
263
|
4otrA |
Crystal structure of btk kinase domain complexed with 6-cyclopropyl-2-[3-[5-[[5-(4-ethylpiperazin-1-yl)-2-pyridyl]amino]-1-methyl-6-oxo-3-pyridyl]-2-(hydroxymethyl)phenyl]-8-fluoro-isoquinolin-1-one |
|
93
|
263
|
4ot5A |
Crystal structure of btk kinase domain complexed with 4-tert-butyl-n-(3-{8-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-benzamide |
|
5
|
57
|
4ommA |
Crystal structure of the intertwined dimer of the c-src tyrosine kinase sh3 domain mutant n113s |
|
88
|
263
|
4otfA |
Crystal structure of the kinase domain of bruton's tyrosine kinase with gdc0834 |
|
85
|
263
|
4nwmA |
Crystal structure of bruton agammaglobulinemia tyrosine kinase complexed with bms-809959 aka 4-tert-butyl-n-[2-me thyl-3-(6-{[4-(morpholine-4-carbonyl)phenyl]amino}-9h- purin-2-yl)phenyl]benzamide |
|
91
|
265
|
4ot6A |
Crystal structure of btk kinase domain complexed with 4-methanesulfonyl-n-(3-{8-[4-(morpholine-4-carbonyl)-phenylamino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-benzamide |
|
87
|
277
|
4o2pA |
Kinase domain of csrc in complex with a substituted pyrazolopyrimidine |
|
6
|
57
|
4omlA |
Crystal structure of the intertwined dimer of the c-src tyrosine kinase sh3 domain mutant q128r |
|
5
|
57
|
4omnA |
Crystal structure of the intertwined dimer of the c-src tyrosine kinase sh3 domain mutant q128e |
|
97
|
329
|
4ny0A |
Crystal structure of ferm domain of human focal adhesion kinase |
|
90
|
263
|
4otqA |
Crystal structure of btk kinase domain complexed with 1-[5-[3-(7-tert-butyl-4-oxo-quinazolin-3-yl)-2-methyl-phenyl]-1-methyl-2-oxo-3-pyridyl]-3-methyl-urea |
|
5
|
57
|
4omqA |
Crystal structure of the intertwined dimer of the c-src tyrosine kinase sh3 domain mutant s94a |
|
6
|
56
|
4ompA |
Crystal structure of the intertwined dimer of the c-src tyrosine kinase sh3 domain mutant q128k |
|
13
|
61
|
4omoA |
Crystal structure of the c-src tyrosine kinase sh3 domain mutant q128e |
|
82
|
277
|
4mxoA |
Human src kinase bound to kinase inhibitor bosutinib |
|
79
|
277
|
4mxyA |
Src m314l t338m double mutant bound to kinase inhibitor bosutinib |
|
79
|
277
|
4mxzA |
Src m314l t338m double mutant bound to kinase inhibitor bosutinib |
|
69
|
263
|
4mf0A |
Itk kinase domain in complex with benzothiazole inhibitor compound 12a (1s,2s)-2-{4-[(dimethylamino)methyl]phenyl}-n-[6-(pyridin-3-yl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide (12a) |
|
84
|
264
|
4m13A |
Crystal structure of itk in complex with compound 8 [4-(carbamoylamino)-1-(7-propoxynaphthalen-1-yl)-1h-pyrazole-3-carboxamide] |
|
75
|
277
|
4mxxA |
Human src a403t mutant bound to kinase inhibitor bosutinib |
|
88
|
264
|
4m0zA |
Crystal structure of itk in complex with compound 5 {4-(carbamoylamino)-1-(7-methoxynaphthalen-1-yl)-1h-pyrazole-3-carboxamide} |
|
112
|
446
|
4lueA |
Crystal structure of hck in complex with 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine (resulting from displacement of skf86002) |
|
74
|
278
|
4mcvA |
Star 12 bound to analog-sensitive src kinase |
|
88
|
263
|
4m14A |
Crystal structure of itk in complex with compound 9 [4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1h-pyrazole-3-carboxamide] |
|
81
|
265
|
4mf1A |
Itk kinase domain in complex with benzothiazole inhibitor 12b (1s,2s)-2-{4-[(dimethylamino)methyl]phenyl}-n-[6-(1h-pyrazol-4-yl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide |
|
84
|
264
|
4m12A |
Crystal structure of itk in complex with compound 7 [4-(carbamoylamino)-1-(7-ethoxynaphthalen-1-yl)-1h-pyrazole-3-carboxamide] |
|
106
|
447
|
4ludA |
Crystal structure of hck in complex with the fluorescent compound skf86002 |
|
84
|
263
|
4m15A |
Crystal structure of itk in complex with compound 9 [4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1h-pyrazole-3-carboxamide] and adp |
|
92
|
263
|
4m0yA |
Crystal structure of itk in complex with compound 1 [4-(carbamoylamino)-1-(naphthalen-1-yl)-1h-pyrazole-3-carboxamide] |
