119
|
386
|
5lxdA |
Crystal structure of dyrk2 in complex with eht 1610 (compound 2) |
114
|
384
|
5lxcA |
Crystal structure of dyrk2 in complex with eht 5372 (compound 1) |
67
|
281
|
5ljjA |
Crystal structure of human mps1 (ttk) in complex with reversine |
80
|
280
|
4cvaA |
Mps1 kinase with 3-aminopyridin-2-one inhibitors |
116
|
336
|
6ft9A |
Crystal structure of clk1 in complex with inhibitor 16 |
74
|
279
|
6h3kA |
Introduction of a methyl group curbs metabolism of pyrido[3,4-d]pyrimidine mps1 inhibitors and enables the discovery of the phase 1 clinical candidate bos172722. |
112
|
337
|
6g33A |
Crystal structure of clk1 in complex with 5-iodotubercidin |
121
|
355
|
6fyrA |
X-ray structure of clk3-kd(gp-[275-632], non-phos.)/cpd-2 at 1.42a |
117
|
340
|
6fylA |
X-ray structure of clk2-kd(136-496)/cx-4945 at 1.95a |
109
|
337
|
6g33B |
Crystal structure of clk1 in complex with 5-iodotubercidin |
118
|
349
|
6fykA |
X-ray structure of clk2-kd(136-496)/indazole1 at 2.39a |
110
|
336
|
6fyiA |
X-ray structure of clk2-kd(130-496)/tg003 at 2.6a |
110
|
348
|
6fypA |
X-ray structure of clk3-kd(gp-[275-632], non-phos.)/cx-4945 at 2.29a |
112
|
334
|
6fyoA |
X-ray structure of clk1-kd(148-484)/cpd-2 at 2.32a |
111
|
332
|
6fyvA |
X-ray structure of clk4-kd(146-480)/cx-4945 at 2.46a |
117
|
356
|
6ft7A |
Crystal structure of clk3 in complex with compound 8a |
121
|
338
|
6ft8A |
Crystal structure of clk1 in complex with inhibitor 8g |
107
|
347
|
6eipA |
Dyrk1a in complex with xmd8-62e |
110
|
347
|
6eijA |
Dyrk1a in complex with hg-8-60-1 |
108
|
347
|
6eiqA |
Dyrk1a in complex with xmd14-124 |
113
|
347
|
6eifA |
Dyrk1a in complex with xmd7-117 |
112
|
347
|
6eilA |
Dyrk1a in complex with xmd8-49 |
104
|
347
|
6eivA |
Dyrk1a in complex with jwd-065 |
102
|
347
|
6ej4A |
Dyrk1a in complex with xmd7-112 |
118
|
347
|
6eisA |
Dyrk1a in complex with jwc-055 |
29
|
127
|
6c4uA |
Engineered fha with myc-ptbd peptide |
77
|
279
|
6b4wA |
Ttk in complex with inhibitor |
120
|
404
|
5ztnA |
The crystal structure of human dyrk2 in complex with curcumin |
115
|
350
|
6a1fA |
Crystal structure of human dyrk1a in complex with compound 14 |
120
|
347
|
6a1gA |
Crystal structure of human dyrk1a in complex with compound 32 |
126
|
395
|
5y86A |
Crystal structure of kinase |
85
|
451
|
5xzwA |
Crystal structure of rad53 1-466 |
86
|
450
|
5xzvA |
Crystal structure of rad53 1-466 in complex with amp-pnp |
109
|
347
|
5a4tA |
Dyrk1a in complex with nitrile benzothiazole fragment |
112
|
347
|
5a54A |
Dyrk1a in complex with nitro benzothiazole fragment |
120
|
347
|
5a4qA |
Dyrk1a in complex with chloro benzothiazole fragment |
109
|
347
|
5a4eA |
Dyrk1a in complex with methoxy benzothiazole fragment |
111
|
347
|
5a4lA |
Dyrk1a in complex with fluoro benzothiazole fragment |
116
|
349
|
4yu2A |
Crystal structure of dyrk1a with harmine-derivatized annh-75 inhibitor |
73
|
281
|
4d2sA |
Human ttk in complex with a dyrk1b inhibitor |
72
|
279
|
4cv8A |
Mps1 kinase with 3-aminopyridin-2-one inhibitors |
76
|
280
|
4cv9A |
Mps1 kinase with 3-aminopyridin-2-one inhibitors |
81
|
279
|
4c4eA |
Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic kinase mps1 |
77
|
280
|
4c4gA |
Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic kinase mps1 |
77
|
279
|
4c4hA |
Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic kinase mps1 |
78
|
279
|
4c4iA |
Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic kinase mps1 |
88
|
280
|
4c4fA |
Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic kinase mps1 |
74
|
279
|
4c4jA |
Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic kinase mps1 |
82
|
279
|
4bi1A |
Scaffold focused virtual screening: prospective application to the discovery of ttk inhibitor |
127
|
409
|
4azfA |
Human dyrk2 in complex with leucettine l41 |