|
129
|
448
|
4k11A |
The structure of 1na in complex with src t338g |
|
100
|
277
|
4l2yB |
Crystal structure of p110alpha complexed with nish2 of p85alpha and compound 9d |
|
24
|
104
|
4k44A |
Auto-inhibition and phosphorylation-induced activation of plc-gamma isozymes |
|
104
|
277
|
4l1bB |
Crystal structure of p110alpha complexed with nish2 of p85alpha |
|
162
|
613
|
4k2rA |
Structural basis for activation of zap-70 by phosphorylation of the sh2-kinase linker |
|
26
|
102
|
4k45A |
Auto-inhibition and phosphorylation-induced activation of plc-gamma isozymes |
|
101
|
277
|
4l23B |
Crystal structure of p110alpha complexed with nish2 of p85alpha and pi-103 |
|
27
|
102
|
4je4A |
Crystal structure of monobody nsa1/shp2 n-sh2 domain complex |
|
46
|
173
|
4jghA |
Structure of the socs2-elongin bc complex bound to an n-terminal fragment of cullin5 |
|
27
|
118
|
4jegA |
Crystal structure of monobody cs1/shp2 c-sh2 domain complex |
|
84
|
261
|
4jpsB |
Co-crystal structures of the lipid kinase pi3k alpha with pan and isoform selective inhibitors |
|
150
|
534
|
4h34A |
Crystal structure of the tyrosine phosphatase shp-2 with q506p mutation |
|
148
|
531
|
4h1oA |
Crystal structure of the tyrosine phosphatase shp-2 with d61g mutation |
|
157
|
534
|
4gwfA |
Crystal structure of the tyrosine phosphatase shp-2 with y279c mutation |
|
25
|
137
|
4gl9E |
Crystal structure of inhibitory protein socs3 in complex with jak2 kinase domain and fragment of gp130 intracellular domain |
|
180
|
627
|
4fl3A |
Structural and biophysical characterization of the syk activation switch |
|
179
|
627
|
4fl2A |
Structural and biophysical characterization of the syk activation switch |
|
37
|
171
|
3qwxX |
Ced-2 1-174 |
|
35
|
170
|
3qwyA |
Ced-2 |
|
245
|
899
|
3psiA |
Crystal structure of the spt6 core domain from saccharomyces cerevisiae, form spt6(239-1451) |
|
139
|
529
|
3ps5A |
Crystal structure of the full-length human protein tyrosine phosphatase shp-1 |
|
48
|
189
|
3psjA |
Crystal structure of the spt6 tandem sh2 domain from saccharomyces cerevisiae, form se-spt6 (1247-1451) |
|
57
|
199
|
3pskA |
Crystal structure of the spt6 tandem sh2 domain from saccharomyces cerevisiae, form native spt6 (1247-1451) |
|
27
|
105
|
3pqzA |
Grb7 sh2 with peptide |
|
25
|
101
|
3ov1A |
Crystal structure of the grb2 sh2 domain in complex with a pyxn-derived tripeptide |
|
24
|
101
|
3oveA |
Crystal structure of the grb2 sh2 domain in complex with a pyxn-derived tripeptide |
|
31
|
163
|
3nhnA |
Crystal structure of the src-family kinase hck sh3-sh2-linker regulatory region |
|
23
|
98
|
3n7yA |
Crystal structure of the grb2 sh2 domain in complex with a 20-membered macrocyclic ligand having the sequence pyvnv |
|
25
|
99
|
3n8mA |
Crystal structure of the grb2 sh2 domain in complex with an acyclic ligand having the sequence pyvnvp |
|
27
|
109
|
3n84A |
Crystal structure of the grb2 sh2 domain in complex with a 23-membered macrocyclic ligand having the sequence pyvnvp |
|
24
|
98
|
3mxcA |
Structures of grb2-sh2 domain and aicd peptide complexes reveal a conformational switch and their functional implications. |
|
22
|
101
|
3mxyA |
Structures of grb2-sh2 domain and aicd peptide complexes reveal a conformational switch and their functional implications. |
|
22
|
99
|
3mazA |
Crystal structure of the human brdg1/stap-1 sh2 domain in complex with the ntal ptyr136 peptide |
|
29
|
107
|
3m7fA |
Crystal structure of the nedd4 c2/grb10 sh2 complex |
|
24
|
100
|
3kfjA |
Crystal structure of the grb2 sh2 domain in complex with a flexible ac-py-e-n-nh2 tripeptide mimic |
|
25
|
100
|
3k2mA |
Crystal structure of monobody ha4/abl1 sh2 domain complex |
|
23
|
101
|
3imdA |
Crystal structure of the grb2 sh2 domain in complex with a flexible ac-py-q-n-nh2 tripeptide mimic |
|
24
|
101
|
3in8A |
Crystal structure of the grb2 sh2 domain in complex with a flexible ac-ptyr-ile-asn-nh2 tripeptide mimic |
|
24
|
101
|
3imjA |
Crystal structure of the grb2 sh2 domain in complex with a cyclopropyl-constrained ac-ptyr-ile-asn-nh2 tripeptide mimic |
|
24
|
99
|
3in7A |
Crystal structure of the grb2 sh2 domain in complex with a cyclopropyl-constrained ac-py-q-n-nh2 tripeptide mimic |
|
15
|
107
|
3hckA |
Nmr ensemble of the uncomplexed human hck sh2 domain, 20 structures |
|
73
|
254
|
3hhmB |
Crystal structure of p110alpha h1047r mutant in complex with nish2 of p85alpha and the drug wortmannin |
|
58
|
253
|
3hizB |
Crystal structure of p110alpha h1047r mutant in complex with nish2 of p85alpha |
|
47
|
226
|
3gqiB |
Crystal structure of activated receptor tyrosine kinase in complex with substrates |
|
22
|
101
|
3eacA |
Crystal structure of sh2 domain of human csk (carboxyl-terminal src kinase), oxidized form. |
|
25
|
102
|
3eazA |
Crystal structure of sh2 domain of human csk (carboxyl-terminal src kinase), c122s mutant. |
|
119
|
446
|
3cxlA |
Crystal structure of human chimerin 1 (chn1) |
|
136
|
553
|
3cwgA |
Unphosphorylated mouse stat3 core fragment |
|
114
|
376
|
3cblA |
Crystal structure of human feline sarcoma viral oncogene homologue (v-fes) in complex with staurosporine and a consensus peptide |
|
25
|
101
|
3c7iA |
X-ray crystal structure of the complex between the grb2-sh2 domain and a flexible ligand, fptvn. |
