|
95
|
290
|
5lwnA |
Crystal structure of jak3 in complex with compound 5 (fm409) |
|
94
|
290
|
5l3aA |
Fragment-based discovery of 6-arylindazole jak inhibitors |
|
91
|
265
|
5kupA |
Bruton's tyrosine kinase (btk) with pyridazinone compound 9 |
|
142
|
529
|
5l04A |
Structure of interferon lambda 1 receptor with human kinase jak1 |
|
89
|
288
|
5khxA |
Crystal structure of jak1 in complex with pf-4950736 |
|
81
|
306
|
5j7bA |
The identification and pharmacological characterization of 6-(tert-butylsulfonyl)-n-(5-fluoro-1h-indazol-3-yl)quinolin-4-amine (gsk583), a highly potent and selective inhibitor of rip2 kinase, gsk583 complex |
|
78
|
275
|
5k9iA |
Crystal structure of c-src in complex with a covalent lysine probe |
|
90
|
287
|
5khwA |
Crystal structure of jak1 in complex with adp |
|
114
|
326
|
5k00A |
Melk in complex with nvs-melk5 |
|
83
|
309
|
5j79A |
The identification and pharmacological characterization of 6-(tert-butylsulfonyl)-n-(5-fluoro-1h-indazol-3-yl)quinolin-4-amine (gsk583), a highly potent and selective inhibitor of rip2 kinase, compound 3 complex |
|
128
|
523
|
5ixiA |
Structure of human jak1 ferm/sh2 in complex with ifnlr1/il10ra chimera |
|
78
|
276
|
5j5sA |
Src kinase in complex with a sulfonamide inhibitor |
|
111
|
523
|
5ixdA |
Structure of human jak1 ferm/sh2 in complex with ifn lambda receptor |
|
115
|
326
|
5ihaA |
Melk in complex with nvs-melk8f |
|
112
|
326
|
5ih8A |
Melk in complex with nvs-melk1 |
|
111
|
326
|
5ih9A |
Melk in complex with nvs-melk8a |
|
109
|
326
|
5ihcA |
Melk in complex with nvs-melk12b |
|
6
|
56
|
5i11A |
Crystal structure of the intertwined form of the src tyrosine kinase sh3 domain t114s-q128r mutant |
|
128
|
447
|
5h0gA |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor (s)-2-(((1r,4s)-4-(4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-n,4-dimethylpentanamide |
|
87
|
284
|
5i4nA |
Crystal structure of the e596a v617f mutant jak2 pseudokinase domain bound to mg-atp |
|
89
|
300
|
5hx8A |
Jak1 complex with 4-[(4-aminocyclohexyl)amino]-3-(1h-benzimidazol-2-yl)-1h-pyridin-2-one |
|
86
|
275
|
5hu9A |
Crystal structure of abl1 in complex with chmfl-074 |
|
125
|
447
|
5h0eA |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor (s)-2-(((1r,4s)-4-(4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-4-methylpentanamide |
|
85
|
273
|
6m9hA |
Jak2 jh2 in complex with diaminopyrimidine jak040 |
|
88
|
287
|
6hd6A |
Abl1 in complex with compound6 and imatinib (sti-571) |
|
0
|
6
|
6h6aE |
Crystal structure of unc119 in complex with lck peptide |
|
93
|
291
|
6glaA |
Crystal structure of jak3 in complex with compound 11 (fm481) |
|
94
|
291
|
6glbA |
Crystal structure of jak3 in complex with compound 20 (fm484) |
|
97
|
292
|
6gl9A |
Crystal structure of jak3 in complex with compound 10 (fm475) |
|
84
|
311
|
6fu5A |
Structure of the kinase domain of human ripk2 in complex with the inhibitor cslp18 |
|
90
|
263
|
6ep9A |
Crystal structure of btk kinase domain complexed with n-[2-methyl-3-[4-methyl-6-[4-(4-methylpiperazine-1-carbonyl)anilino]-5-oxo-pyrazin-2-yl]phenyl]-4-(1-piperidyl)benzamide |
|
124
|
449
|
6f3fA |
Autoinhibited src kinase bound to adp |
|
90
|
312
|
6es0A |
Crystal structure of the kinase domain of human ripk2 in complex with the activation loop targeting inhibitor cs-r35 |
|
135
|
481
|
6e2qA |
Structure of human jak2 ferm/sh2 in complex with erythropoietin receptor |
|
126
|
478
|
6e2pA |
Structure of human jak2 ferm/sh2 in complex with leptin receptor |
|
93
|
270
|
6e4fA |
Crystal structure of arq 531 in complex with the kinase domain of btk |
|
86
|
288
|
6dbnA |
Jak1 with compound 23 |
|
85
|
267
|
6di3A |
Crystal structure of btk in complex with fragment ligand |
|
87
|
268
|
6di9A |
Crystal structure of btk in complex with covalent inhibitor |
|
89
|
290
|
6dbmA |
Tyk2 with compound 23 |
|
88
|
271
|
6di5A |
Crystal structure of btk in complex with covalent inhibitor |
|
91
|
295
|
6drwA |
Jak2 jh1 in complex with jnj-7706621 (crystal form 2) |
|
93
|
290
|
6dbkA |
Tyk2 with compound 8 |
|
93
|
262
|
6cz2A |
Structure of the ptk6 kinase domain |
|
90
|
261
|
6cz4A |
Structure of the ptk6 kinase domain bound to a type ii inhibitor 2-{[(3r,4s)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1h-imidazol-4-yl)pyridine-3-carboxamide |
|
87
|
262
|
6cz3A |
Structure of the ptk6 kinase domain bound to a type i inhibitor (3-fluoro-4-{[6-methyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone |
|
79
|
286
|
6c7yA |
Crystal structure of inhibitory protein socs1 in complex with jak1 kinase domain |
|
53
|
125
|
6bz3A |
Complex structure of fak fat domain and dcc p3 motif |
|
83
|
272
|
6bs0A |
Jak2 jh2 in complex with 63552444 |
|
81
|
270
|
6bl8A |
Predicting the conformational variability of abl tyrosine kinase using molecular dynamics simulations and markov state models |
