1FD4A

Human beta-defensin 2
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
41
structure length
41
Chain Sequence
GIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of human beta-defensin-2 shows evidence of higher order oligomerization.
pubmed doi rcsb
molecule tags Antimicrobial peptide
molecule keywords BETA-DEFENSIN 2
total genus 9
structure length 41
sequence length 41
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
ec nomenclature
pdb deposition date 2000-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00711 Defensin_beta Beta defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.360.10 Alpha Beta Roll Antimicrobial Peptide, Beta-defensin 2; Chain A Antimicrobial Peptide, Beta-defensin 2; Chain A 1fd4A00
1FD4A 1FD3A 2LWLA 1FQQA 2LXOA 1KJ6A
chains in the Genus database with same CATH superfamily
1FD4A 1FD3A 4E4DR 3MI8D 2LWLA 2MJKA 1FQQA 3QD6R 2LXOA 3MHDD 1KJ6A 2UWIA
chains in the Genus database with same CATH topology
1FD4A 1FD3A 4E4DR 3MI8D 2LWLA 2MJKA 1FQQA 3QD6R 2LXOA 3MHDD 1KJ6A 2UWIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FD4 A;  1FD3 A;  2LWL A;  1FQQ A;  2LXO A;  1KJ6 A; 
#chains in the Genus database with same CATH topology
 1FD4 A;  1FD3 A;  4E4D R;  3MI8 D;  2LWL A;  2MJK A;  1FQQ A;  3QD6 R;  2LXO A;  3MHD D;  1KJ6 A;  2UWI A; 
#chains in the Genus database with same CATH homology
 1FD4 A;  1FD3 A;  4E4D R;  3MI8 D;  2LWL A;  2MJK A;  1FQQ A;  3QD6 R;  2LXO A;  3MHD D;  1KJ6 A;  2UWI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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