2LWLA

Structural basis for the interaction of human β-defensin 6 and its putative chemokine receptor ccr2 and breast cancer microvesicles
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
45
structure length
45
Chain Sequence
FFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPSGSIID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Antimicrobial protein
molecule keywords Beta-defensin 106
publication title Structural Basis for the Interaction of Human beta-Defensin 6 and Its Putative Chemokine Receptor CCR2 and Breast Cancer Microvesicles.
pubmed doi rcsb
source organism Homo sapiens
total genus 9
structure length 45
sequence length 45
ec nomenclature
pdb deposition date 2012-08-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13841 Defensin_beta_2 Beta defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.360.10 Alpha Beta Roll Antimicrobial Peptide, Beta-defensin 2; Chain A Antimicrobial Peptide, Beta-defensin 2; Chain A 2lwlA00
2LXOA 1FD4A 1FQQA 1KJ6A 1FD3A 2LWLA
chains in the Genus database with same CATH superfamily
2LXOA 3QD6R 2UWIA 1FD4A 1FQQA 3MI8D 4E4DR 2MJKA 1KJ6A 1FD3A 2LWLA 3MHDD
chains in the Genus database with same CATH topology
2LXOA 3QD6R 2UWIA 1FD4A 1FQQA 3MI8D 4E4DR 2MJKA 1KJ6A 1FD3A 2LWLA 3MHDD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LXO A;  1FD4 A;  1FQQ A;  1KJ6 A;  1FD3 A;  2LWL A; 
#chains in the Genus database with same CATH topology
 2LXO A;  3QD6 R;  2UWI A;  1FD4 A;  1FQQ A;  3MI8 D;  4E4D R;  2MJK A;  1KJ6 A;  1FD3 A;  2LWL A;  3MHD D; 
#chains in the Genus database with same CATH homology
 2LXO A;  3QD6 R;  2UWI A;  1FD4 A;  1FQQ A;  3MI8 D;  4E4D R;  2MJK A;  1KJ6 A;  1FD3 A;  2LWL A;  3MHD D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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