1KJ6A

Solution structure of human beta-defensin 3
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
45
structure length
45
Chain Sequence
GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus.
pubmed doi rcsb
molecule tags Antibiotic
source organism Homo sapiens
molecule keywords Beta-defensin 3
total genus 5
structure length 45
sequence length 45
ec nomenclature
pdb deposition date 2001-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00711 Defensin_beta Beta defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.360.10 Alpha Beta Roll Antimicrobial Peptide, Beta-defensin 2; Chain A Antimicrobial Peptide, Beta-defensin 2; Chain A 1kj6A00
2LWLA 1FD3A 1FD4A 2LXOA 1FQQA 1KJ6A
chains in the Genus database with same CATH superfamily
2LWLA 1FD3A 1FD4A 4E4DR 2MJKA 2LXOA 3QD6R 2UWIA 1FQQA 3MI8D 1KJ6A 3MHDD
chains in the Genus database with same CATH topology
2LWLA 1FD3A 1FD4A 4E4DR 2MJKA 2LXOA 3QD6R 2UWIA 1FQQA 3MI8D 1KJ6A 3MHDD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LWL A;  1FD3 A;  1FD4 A;  2LXO A;  1FQQ A;  1KJ6 A; 
#chains in the Genus database with same CATH topology
 2LWL A;  1FD3 A;  1FD4 A;  4E4D R;  2MJK A;  2LXO A;  3QD6 R;  2UWI A;  1FQQ A;  3MI8 D;  1KJ6 A;  3MHD D; 
#chains in the Genus database with same CATH homology
 2LWL A;  1FD3 A;  1FD4 A;  4E4D R;  2MJK A;  2LXO A;  3QD6 R;  2UWI A;  1FQQ A;  3MI8 D;  1KJ6 A;  3MHD D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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