The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
274
|
sequence length |
721
|
structure length |
717
|
Chain Sequence |
EISLSAEFIDRVKASVKPHWGKLGWVTYKRTYARWLPEKGRSENWDETVKRVVEGNINLDPRLQDSPSLELKQSLTEEAERLYKLIYGLGATPSGRNLWISGTDYQRRTGDSLNNCWFVAIRPQKYGDSKIVPSYLGKQEKAVSMPFSFLFDELMKGGGVGFSVARSNISQIPRVDFAIDLQLVVDETSESYDASVKVGAVGKNELVQDADSIYYRLPDTREGWVLANALLIDLHFAQTNPDRKQKLILDLSDIRPYGAEIHGFGGTASGPMPLISMLLDVNEVLNNKAGGRLTAVDAADICNLIGKAVVAGNAELALGSNDDQDFISMKQDQEKLMHHRWASNNSVAVDSAFSGYQPIAAGIRENGEPGIVNLDLSKNYGRIVDGYQAGIDGDVEGTNPCGEISLANGEPCNLFEVFPLIAEEQGWDLQEVFALAARYAKRVTFSPYDWEISREIIQKNRRIGISMSGIQDWLLTRLGNRVVTGFKDDFDPETHEAIKVPVYDKRAIKMVDQLYKAVVKADQDYSKTLGCNESIKHTTVKPSGTVAKLAGASEGMHFHYGAYLIQRIRFQDSDPLLPALKACGYRTEADIYTENTTCVEFPIKAVGADNPNFASAGTVSIAEQFATQAFLQTYWSDNAVSCTITFQDSEGDQVESLLRQYRFITKSTSLLPYFGGSLQQAPKEPIDKETYEKRSQEITGNVEEVFSQLNSDVKDLE
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer.
pubmed doi rcsb |
| molecule keywords |
RIBONUCLEOSIDE TRIPHOSPHATE REDUCTASE
|
| molecule tags |
Oxidoreductase
|
| source organism |
Lactobacillus leichmannii
|
| total genus |
274
|
| structure length |
717
|
| sequence length |
721
|
| chains with identical sequence |
B, C, D
|
| ec nomenclature |
ec
1.17.4.2: Ribonucleoside-triphosphate reductase (thioredoxin). |
| pdb deposition date | 2002-02-18 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02867 | Ribonuc_red_lgC | Ribonucleotide reductase, barrel domain |
| A | PF17975 | RNR_Alpha | Ribonucleotide reductase alpha domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Alpha-Beta Barrel | Anaerobic Ribonucleotide-triphosphate Reductase Large Chain | Anaerobic Ribonucleotide-triphosphate Reductase Large Chain | ||
| Alpha Beta | 2-Layer Sandwich | b-12 dependent (class ii) ribonucleotide reductase, Chain A, Domain 2 | b-12 dependent (class ii) ribonucleotide reductase, Chain A, Domain 2 | ||
| Alpha Beta | Alpha-Beta Complex | b-12 dependent (class ii) ribonucleotide reductase, chain A, domain 3 | b-12 dependent (class ii) ribonucleotide reductase, chain A, domain 3 |
#chains in the Genus database with same CATH superfamily 2ZLF A; 3HNC A; 1ZZD A; 2CVY A; 3K8T A; 1H79 A; 1QHM A; 5CNV A; 1H7B A; 7R1R A; 2CVS A; 2CVX A; 3S87 A; 5R1R A; 1R1R A; 4R1R A; 2YAJ A; 3TBA A; 3S8B A; 1H78 A; 3O0Q A; 2BQ1 E; 2XAV A; 2XAY A; 5CNT A; 2XAP A; 1H7A A; 3TB9 A; 2EUD A; 1PEO A; 2CVT A; 2XAX A; 3HND A; 4X3V A; 3HNE A; 1XJJ A; 1H17 A; 1H16 A; 2XAW A; 3O0N A; 2WGH A; 4ERM A; 1L1L A; 1RLR A; 2CVU A; 1R9D A; 1PEU A; 3S8C A; 1R8W A; 2Y8N A; 3HNF A; 2R1R A; 1HK8 A; 2ZLG A; 5CNS A; 2PFL A; 1CM5 A; 5CNU A; 1XJM A; 1ZYZ A; 2X0X A; 2HA9 A; 2CVV A; 1PEQ A; 1MZO A; 2F3O A; 2XO5 A; 3PFL A; 3RSR A; 1XJE A; 3R1R A; 6R1R A; 1H18 A; 4MTJ A; 1XJF A; 1XJK A; 2XAZ A; 2CVW A; 3O0O A; 1XJG A; 3S8A A; 1XJN A; 1PEM A; 2XAK A; 2XO4 A; #chains in the Genus database with same CATH topology 2ZLF A; 3HNC A; 1ZZD A; 2CVY A; 3K8T A; 1H79 A; 1QHM A; 5CNV A; 1H7B A; 7R1R A; 2CVS A; 2CVX A; 3S87 A; 5FAW A; 5R1R A; 1R1R A; 5FAV A; 4R1R A; 2YAJ A; 3TBA A; 3S8B A; 1H78 A; 3O0Q A; 2BQ1 E; 5FAY A; 2XAV A; 2XAY A; 5CNT A; 2XAP A; 1H7A A; 3TB9 A; 2EUD A; 1PEO A; 2CVT A; 2XAX A; 3HND A; 4X3V A; 3HNE A; 1XJJ A; 1H17 A; 1H16 A; 2XAW A; 3O0N A; 2WGH A; 4ERM A; 1L1L A; 1RLR A; 2CVU A; 5A0U A; 1R9D A; 1PEU A; 5A0Z A; 3S8C A; 1R8W A; 2Y8N A; 3HNF A; 2R1R A; 1HK8 A; 2ZLG A; 5CNS A; 2PFL A; 1CM5 A; 5CNU A; 1XJM A; 5FAU A; 1ZYZ A; 2X0X A; 2HA9 A; 2CVV A; 1PEQ A; 1MZO A; 2F3O A; 2XO5 A; 3PFL A; 3RSR A; 1XJE A; 3R1R A; 6R1R A; 1H18 A; 4MTJ A; 1XJF A; 1XJK A; 2XAZ A; 2CVW A; 3O0O A; 1XJG A; 1XJN A; 3S8A A; 1PEM A; 5KDP A; 2XAK A; 2XO4 A; #chains in the Genus database with same CATH homology 2ZLF A; 3HNC A; 1ZZD A; 2CVY A; 3K8T A; 1H79 A; 1QHM A; 5CNV A; 1H7B A; 7R1R A; 2CVS A; 2CVX A; 3S87 A; 5FAW A; 5R1R A; 1R1R A; 5FAV A; 4R1R A; 2YAJ A; 3TBA A; 3S8B A; 1H78 A; 3O0Q A; 2BQ1 E; 5FAY A; 2XAV A; 2XAY A; 5CNT A; 2XAP A; 1H7A A; 3TB9 A; 2EUD A; 1PEO A; 2CVT A; 2XAX A; 3HND A; 4X3V A; 3HNE A; 1XJJ A; 1H17 A; 1H16 A; 2XAW A; 3O0N A; 2WGH A; 4ERM A; 1L1L A; 1RLR A; 2CVU A; 5A0U A; 1R9D A; 1PEU A; 5A0Z A; 3S8C A; 1R8W A; 2Y8N A; 3HNF A; 2R1R A; 1HK8 A; 2ZLG A; 5CNS A; 2PFL A; 1CM5 A; 5CNU A; 1XJM A; 5FAU A; 1ZYZ A; 2X0X A; 2HA9 A; 2CVV A; 1PEQ A; 1MZO A; 2F3O A; 2XO5 A; 3PFL A; 3RSR A; 1XJE A; 3R1R A; 6R1R A; 1H18 A; 4MTJ A; 1XJF A; 1XJK A; 2XAZ A; 2CVW A; 3O0O A; 1XJG A; 1XJN A; 3S8A A; 1PEM A; 5KDP A; 2XAK A; 2XO4 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
