1P4QB

Solution structure of the cited2 transactivation domain in complex with the p300 ch1 domain
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
101
structure length
101
Chain Sequence
MGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2.
pubmed doi rcsb
molecule tags Transcription/transferase
source organism Homo sapiens
molecule keywords Cbp/p300-interacting transactivator 2
total genus 25
structure length 101
sequence length 101
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2003-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02135 zf-TAZ TAZ zinc finger
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1020.10 Mainly Alpha Up-down Bundle CREB-binding Protein; Chain A TAZ domain 1p4qB00
3T92A 1F81A 1L8CA 2KA6A 2KJEA 3P57P 3IO2A 2KA4A 5HP0A 2K8FA 1R8UB 2MH0B 1P4QB 2MZDA 1U2NA 2LWWA 1L3EB
chains in the Genus database with same CATH superfamily
3T92A 1F81A 1L8CA 2KA6A 2KJEA 3P57P 3IO2A 2KA4A 5HP0A 2K8FA 1R8UB 2MH0B 1P4QB 2MZDA 1U2NA 2LWWA 1L3EB
chains in the Genus database with same CATH topology
3T92A 1F81A 1L8CA 2KA6A 2KJEA 3P57P 3IO2A 2KA4A 5HP0A 2K8FA 1R8UB 2MH0B 1P4QB 2MZDA 1U2NA 2LWWA 1L3EB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T92 A;  1F81 A;  1L8C A;  2KA6 A;  2KJE A;  3P57 P;  3IO2 A;  2KA4 A;  5HP0 A;  2K8F A;  1R8U B;  2MH0 B;  1P4Q B;  2MZD A;  1U2N A;  2LWW A;  1L3E B; 
#chains in the Genus database with same CATH topology
 3T92 A;  1F81 A;  1L8C A;  2KA6 A;  2KJE A;  3P57 P;  3IO2 A;  2KA4 A;  5HP0 A;  2K8F A;  1R8U B;  2MH0 B;  1P4Q B;  2MZD A;  1U2N A;  2LWW A;  1L3E B; 
#chains in the Genus database with same CATH homology
 3T92 A;  1F81 A;  1L8C A;  2KA6 A;  2KJE A;  3P57 P;  3IO2 A;  2KA4 A;  5HP0 A;  2K8F A;  1R8U B;  2MH0 B;  1P4Q B;  2MZD A;  1U2N A;  2LWW A;  1L3E B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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