1QLXA

Human prion protein
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
104
structure length
104
Chain Sequence
LGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title NMR Solution Structure of the Human Prion Protein
pubmed doi rcsb
molecule tags Prion protein
source organism Homo sapiens
molecule keywords PRION PROTEIN
total genus 33
structure length 104
sequence length 104
ec nomenclature
pdb deposition date 1999-09-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.790.10 Mainly Alpha Orthogonal Bundle Major Prion Protein Prion/Doppel protein, beta-ribbon domain 1qlxA00
4DGIA 1I17A 1I4MA 1E1WA 2KU4A 1E1UA 2K56A 1XYKA 1XYQA 2L39A 2L1KA 1QM2A 1FO7A 1TPXA 1Y16A 2K1DA 1QM0A 1U5LA 1FKCA 3HESA 1DX1A 3HAKA 2JOMA 3HEQA 3HJ5A 1QLXA 1XYXA 2JOHA 1E1SA 2MV8A 2KUNA 2KU6A 2L1EA 2LH8A 1E1JA 1TQBA 3HAFA 1HJMA 1XYJA 1HJNA 2L1HA 1XYWA 2KTMA 2KFOA 1LG4A 1B10A 2KU5A 2LEJA 3HERA 2W9EA 1DX0A 2L40A 2LSBA 1Y2SA 1DWZA 1H0LA 1AG2A 3HJXA 1E1PA 2K5OA 2L1DA 1Y15A 1UW3A 1U3MA 1E1GA 2KFMA 2FJ3A 2KFLA 1XU0A 1QLZA 2LFTA 1XYUA 1QM1A 1DWYA 1QM3A 1TQCA 3O79A
chains in the Genus database with same CATH superfamily
4DGIA 1I17A 1I4MA 1E1WA 2KU4A 1E1UA 2K56A 1XYKA 1XYQA 2L39A 2L1KA 1QM2A 1FO7A 1TPXA 2KZCA 1Y16A 2K1DA 1QM0A 1U5LA 1FKCA 3HESA 1DX1A 3HAKA 2JOMA 3HEQA 3HJ5A 1QLXA 1XYXA 2JOHA 1E1SA 2MV8A 2KUNA 2KU6A 2L1EA 2LH8A 1E1JA 1TQBA 3HAFA 2MDZA 1HJMA 1XYJA 1HJNA 2L1HA 1XYWA 2KTMA 2KFOA 1LG4A 1B10A 2KU5A 2LEJA 3HERA 2W9EA 1DX0A 2L40A 2LSBA 1Y2SA 1DWZA 1H0LA 1AG2A 3HJXA 1E1PA 2K5OA 2LL0A 2L1DA 1Y15A 1UW3A 1U3MA 1E1GA 2KFMA 2FJ3A 2KFLA 1XU0A 1QLZA 2LFTA 1XYUA 1QM1A 1DWYA 1QM3A 1TQCA 3O79A
chains in the Genus database with same CATH topology
4DGIA 1I17A 1I4MA 1E1WA 2KU4A 1E1UA 2K56A 1XYKA 1XYQA 2L39A 2L1KA 1QM2A 1FO7A 1TPXA 1Y16A 2K1DA 1QM0A 1U5LA 1FKCA 3HESA 1DX1A 3HAKA 2JOMA 3HEQA 3HJ5A 1QLXA 1XYXA 2JOHA 1E1SA 2MV8A 2KUNA 2KU6A 2L1EA 2LH8A 1E1JA 1TQBA 3HAFA 1HJMA 1XYJA 1HJNA 2L1HA 1XYWA 2KTMA 2KFOA 1LG4A 1B10A 2KU5A 2LEJA 3HERA 2W9EA 1DX0A 2L40A 2LSBA 1Y2SA 1DWZA 1H0LA 1AG2A 3HJXA 1E1PA 2K5OA 2L1DA 1Y15A 1UW3A 1U3MA 1E1GA 2KFMA 2FJ3A 2KFLA 1XU0A 1QLZA 2LFTA 1XYUA 1QM1A 1DWYA 1QM3A 1TQCA 3O79A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DGI A;  1I17 A;  1I4M A;  1E1W A;  2KU4 A;  1E1U A;  2K56 A;  1XYK A;  1XYQ A;  2L39 A;  2L1K A;  1QM2 A;  1FO7 A;  1TPX A;  1Y16 A;  2K1D A;  1QM0 A;  1U5L A;  1FKC A;  3HES A;  1DX1 A;  3HAK A;  2JOM A;  3HEQ A;  3HJ5 A;  1QLX A;  1XYX A;  2JOH A;  1E1S A;  2MV8 A;  2KUN A;  2KU6 A;  2L1E A;  2LH8 A;  1E1J A;  1TQB A;  3HAF A;  1HJM A;  1XYJ A;  1HJN A;  2L1H A;  1XYW A;  2KTM A;  2KFO A;  1LG4 A;  1B10 A;  2KU5 A;  2LEJ A;  3HER A;  2W9E A;  1DX0 A;  2L40 A;  2LSB A;  1Y2S A;  1DWZ A;  1H0L A;  1AG2 A;  3HJX A;  1E1P A;  2K5O A;  2L1D A;  1Y15 A;  1UW3 A;  1U3M A;  1E1G A;  2KFM A;  2FJ3 A;  2KFL A;  1XU0 A;  1QLZ A;  2LFT A;  1XYU A;  1QM1 A;  1DWY A;  1QM3 A;  1TQC A;  3O79 A; 
#chains in the Genus database with same CATH topology
 4DGI A;  1I17 A;  1I4M A;  1E1W A;  2KU4 A;  1E1U A;  2K56 A;  1XYK A;  1XYQ A;  2L39 A;  2L1K A;  1QM2 A;  1FO7 A;  1TPX A;  2KZC A;  1Y16 A;  2K1D A;  1QM0 A;  1U5L A;  1FKC A;  3HES A;  1DX1 A;  3HAK A;  2JOM A;  3HEQ A;  3HJ5 A;  1QLX A;  1XYX A;  2JOH A;  1E1S A;  2MV8 A;  2KUN A;  2KU6 A;  2L1E A;  2LH8 A;  1E1J A;  1TQB A;  3HAF A;  2MDZ A;  1HJM A;  1XYJ A;  1HJN A;  2L1H A;  1XYW A;  2KTM A;  2KFO A;  1LG4 A;  1B10 A;  2KU5 A;  2LEJ A;  3HER A;  2W9E A;  1DX0 A;  2L40 A;  2LSB A;  1Y2S A;  1DWZ A;  1H0L A;  1AG2 A;  3HJX A;  1E1P A;  2K5O A;  2LL0 A;  2L1D A;  1Y15 A;  1UW3 A;  1U3M A;  1E1G A;  2KFM A;  2FJ3 A;  2KFL A;  1XU0 A;  1QLZ A;  2LFT A;  1XYU A;  1QM1 A;  1DWY A;  1QM3 A;  1TQC A;  3O79 A; 
#chains in the Genus database with same CATH homology
 4DGI A;  1I17 A;  1I4M A;  1E1W A;  2KU4 A;  1E1U A;  2K56 A;  1XYK A;  1XYQ A;  2L39 A;  2L1K A;  1QM2 A;  1FO7 A;  1TPX A;  1Y16 A;  2K1D A;  1QM0 A;  1U5L A;  1FKC A;  3HES A;  1DX1 A;  3HAK A;  2JOM A;  3HEQ A;  3HJ5 A;  1QLX A;  1XYX A;  2JOH A;  1E1S A;  2MV8 A;  2KUN A;  2KU6 A;  2L1E A;  2LH8 A;  1E1J A;  1TQB A;  3HAF A;  1HJM A;  1XYJ A;  1HJN A;  2L1H A;  1XYW A;  2KTM A;  2KFO A;  1LG4 A;  1B10 A;  2KU5 A;  2LEJ A;  3HER A;  2W9E A;  1DX0 A;  2L40 A;  2LSB A;  1Y2S A;  1DWZ A;  1H0L A;  1AG2 A;  3HJX A;  1E1P A;  2K5O A;  2L1D A;  1Y15 A;  1UW3 A;  1U3M A;  1E1G A;  2KFM A;  2FJ3 A;  2KFL A;  1XU0 A;  1QLZ A;  2LFT A;  1XYU A;  1QM1 A;  1DWY A;  1QM3 A;  1TQC A;  3O79 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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