1UW0A

Solution structure of the zinc-finger domain from dna ligase iiia
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
117
structure length
117
Chain Sequence
MAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIGKVVPNPFSESGGDMKEWYHIKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQITQHIADLSSKAAGTPKKKAVVQAKLTT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
molecule keywords DNA LIGASE III
publication title Solution Structure and DNA Binding of the Zinc-Finger Domain from DNA Ligase Iiialpha
pubmed doi rcsb
source organism Homo sapiens
total genus 12
structure length 117
sequence length 117
ec nomenclature ec 6.5.1.1: DNA ligase (ATP).
pdb deposition date 2004-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00645 zf-PARP Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1740.10 Alpha Beta 2-Layer Sandwich first zn-finger domain of poly(adp-ribose) polymerase-1 Zinc finger, PARP-type 1uw0A01
2CS2A 3ODAA 4DQYA 4OQAA 2DMJA 2L30A 2L31A 3ODCA 3ODEA 3OD8A 4AV1A 4OPXA 4OQBA 1V9XA 2N8AA 1UW0A
chains in the Genus database with same CATH superfamily
5FLXa 4OQAA 2N8AA 1UW0A 2CS2A 4DQYA 5IT9a 4AV1A 3JAMa 3ODCA 3ODEA 4OQBA 1V9XA 5A2Qa 3ODAA 2DMJA 2L30A 3OD8A 3J81a 4OPXA 3J7A3 2L31A 3J80a 5LL6e
chains in the Genus database with same CATH topology
2CS2A 3ODAA 4DQYA 4OQAA 2DMJA 2L30A 2L31A 3ODCA 3ODEA 3OD8A 4AV1A 4OPXA 4OQBA 1V9XA 2N8AA 1UW0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CS2 A;  3ODA A;  4DQY A;  4OQA A;  2DMJ A;  2L30 A;  2L31 A;  3ODC A;  3ODE A;  3OD8 A;  4AV1 A;  4OPX A;  4OQB A;  1V9X A;  2N8A A;  1UW0 A; 
#chains in the Genus database with same CATH topology
 5FLX a;  4OQA A;  2N8A A;  1UW0 A;  2CS2 A;  4DQY A;  5IT9 a;  4AV1 A;  3JAM a;  3ODC A;  3ODE A;  4OQB A;  1V9X A;  5A2Q a;  3ODA A;  2DMJ A;  2L30 A;  3OD8 A;  3J81 a;  4OPX A;  3J7A 3;  2L31 A;  3J80 a;  5LL6 e; 
#chains in the Genus database with same CATH homology
 2CS2 A;  3ODA A;  4DQY A;  4OQA A;  2DMJ A;  2L30 A;  2L31 A;  3ODC A;  3ODE A;  3OD8 A;  4AV1 A;  4OPX A;  4OQB A;  1V9X A;  2N8A A;  1UW0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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