1W85I

The crystal structure of pyruvate dehydrogenase e1 bound to the peripheral subunit binding domain of e2
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
42
structure length
42
Chain Sequence
RVIAMPSVRKYAREKGVDIRLVQGTGKNGRVLKEDIDAFLAG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
molecule keywords PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT
publication title A molecular switch and proton wire synchronize the active sites in thiamine enzymes.
pubmed doi rcsb
source organism Geobacillus stearothermophilus
total genus 11
structure length 42
sequence length 42
chains with identical sequence J
ec nomenclature ec 2.3.1.12: Dihydrolipoyllysine-residue acetyltransferase.
pdb deposition date 2004-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF02817 E3_binding e3 binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.320.10 Few Secondary Structures Irregular Dihydrolipoamide Transferase E3-binding domain 1w85I00
1W4JA 1ZY8K 2F60K 2PDEA 2F5ZK 1BALA 2PDDA 1W85I 3RNME 4QOYE 1W4GA 2EQ9C 1W4EA 1W4IA 1ZWVA 3DVAI 1W4KA 1W88I 2BTHA 1EBDC 1W4HA 2BTGA 1W3DA 3DV0I 1W4FA 2WXCA
chains in the Genus database with same CATH superfamily
1W4JA 1ZY8K 2F60K 2PDEA 2F5ZK 1BALA 2PDDA 1W85I 3RNME 4QOYE 1W4GA 2EQ9C 1W4EA 1W4IA 1ZWVA 3DVAI 1W4KA 1W88I 2BTHA 1EBDC 1W4HA 2BTGA 1W3DA 3DV0I 1W4FA 2WXCA
chains in the Genus database with same CATH topology
1W4JA 1ZY8K 2F60K 2PDEA 2F5ZK 1BALA 2PDDA 1W85I 3RNME 4QOYE 1W4GA 2EQ9C 1W4EA 1W4IA 1ZWVA 3DVAI 1W4KA 1W88I 2BTHA 1EBDC 1W4HA 2BTGA 1W3DA 3DV0I 1W4FA 2WXCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W4J A;  1ZY8 K;  2F60 K;  2PDE A;  2F5Z K;  1BAL A;  2PDD A;  1W85 I;  3RNM E;  4QOY E;  1W4G A;  2EQ9 C;  1W4E A;  1W4I A;  1ZWV A;  3DVA I;  1W4K A;  1W88 I;  2BTH A;  1EBD C;  1W4H A;  2BTG A;  1W3D A;  3DV0 I;  1W4F A;  2WXC A; 
#chains in the Genus database with same CATH topology
 1W4J A;  1ZY8 K;  2F60 K;  2PDE A;  2F5Z K;  1BAL A;  2PDD A;  1W85 I;  3RNM E;  4QOY E;  1W4G A;  2EQ9 C;  1W4E A;  1W4I A;  1ZWV A;  3DVA I;  1W4K A;  1W88 I;  2BTH A;  1EBD C;  1W4H A;  2BTG A;  1W3D A;  3DV0 I;  1W4F A;  2WXC A; 
#chains in the Genus database with same CATH homology
 1W4J A;  1ZY8 K;  2F60 K;  2PDE A;  2F5Z K;  1BAL A;  2PDD A;  1W85 I;  3RNM E;  4QOY E;  1W4G A;  2EQ9 C;  1W4E A;  1W4I A;  1ZWV A;  3DVA I;  1W4K A;  1W88 I;  2BTH A;  1EBD C;  1W4H A;  2BTG A;  1W3D A;  3DV0 I;  1W4F A;  2WXC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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