1YHQX

Crystal structure of azithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
82
structure length
82
Chain Sequence
ERVVTIPLRDARAEPNHKRADKAMILIREHLAKHFSVDEDAVRLDPSINEAAWARGRANTPSKIRVRAARFEEEGEAIVEAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 21
structure length 82
sequence length 82
ec nomenclature
pdb deposition date 2005-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01198 Ribosomal_L31e Ribosomal protein L31e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.440.10 Alpha Beta Roll Ribosomal Protein L31e; Chain: W; Ribosomal Protein L31e; Chain: W; 1yhqX00
3CPWW 3CCQX 1YITX 2OTJX 1VQ6X 1W2BW 1VQKX 1VQ9X 1YIJX 1S72X 3G71X 3CCUX 1QVFW 3CCJX 3CCLX 3OW2W 1VQOX 1YHQX 1NJIY 1VQ4X 1Q7YY 1YI2X 3CXCW 3CCRX 1KC8Y 1VQ7X 1QVGW 1YJNX 1M90Y 1VQ8X 1KQSW 1YJWX 1VQMX 2QA4X 1N8RY 3CCEX 1Q81Y 1K8AY 1M1KY 3I56X 1K9MY 3CCMX 3G6EX 3CMEX 1VQ5X 3CCVX 1Q82Y 1Q86Y 1VQNX 3CCSX 3I55X 3G4SX 3CD6X 1K73Y 3CMAX 2QEXX 3CC4X 1VQLX 3CC7X 1KD1Y 2OTLX 3CC2X 1JJ2W 1YJ9X 1VQPX
chains in the Genus database with same CATH superfamily
3CPWW 3CCQX 1YITX 2OTJX 1VQ6X 1W2BW 1VQKX 1VQ9X 1YIJX 1S72X 3G71X 3CCUX 1QVFW 3CCJX 3CCLX 3OW2W 1VQOX 1YHQX 1NJIY 1VQ4X 1Q7YY 1YI2X 3CXCW 3CCRX 1KC8Y 1VQ7X 1QVGW 1YJNX 1M90Y 1VQ8X 1KQSW 1YJWX 1VQMX 2QA4X 1N8RY 3CCEX 1Q81Y 1K8AY 1M1KY 3I56X 1K9MY 3CCMX 3G6EX 3CMEX 1VQ5X 3CCVX 1Q82Y 1Q86Y 1VQNX 3CCSX 3I55X 3G4SX 3CD6X 1K73Y 3CMAX 2QEXX 3CC4X 1VQLX 3CC7X 1KD1Y 2OTLX 3CC2X 1JJ2W 1YJ9X 1VQPX
chains in the Genus database with same CATH topology
3CPWW 3CCQX 1YITX 2OTJX 1VQ6X 1W2BW 1VQKX 1VQ9X 1YIJX 1S72X 3G71X 3CCUX 1QVFW 3CCJX 3CCLX 3OW2W 1VQOX 1YHQX 1NJIY 1VQ4X 1Q7YY 1YI2X 3CXCW 3CCRX 1KC8Y 1VQ7X 1QVGW 1YJNX 1M90Y 1VQ8X 1KQSW 1YJWX 1VQMX 2QA4X 1N8RY 3CCEX 1Q81Y 1K8AY 1M1KY 3I56X 1K9MY 3CCMX 3G6EX 3CMEX 1VQ5X 3CCVX 1Q82Y 1Q86Y 1VQNX 3CCSX 3I55X 3G4SX 3CD6X 1K73Y 3CMAX 2QEXX 3CC4X 1VQLX 3CC7X 1KD1Y 2OTLX 3CC2X 1JJ2W 1YJ9X 1VQPX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CPW W;  3CCQ X;  1YIT X;  2OTJ X;  1VQ6 X;  1W2B W;  1VQK X;  1VQ9 X;  1YIJ X;  1S72 X;  3G71 X;  3CCU X;  1QVF W;  3CCJ X;  3CCL X;  3OW2 W;  1VQO X;  1YHQ X;  1NJI Y;  1VQ4 X;  1Q7Y Y;  1YI2 X;  3CXC W;  3CCR X;  1KC8 Y;  1VQ7 X;  1QVG W;  1YJN X;  1M90 Y;  1VQ8 X;  1KQS W;  1YJW X;  1VQM X;  2QA4 X;  1N8R Y;  3CCE X;  1Q81 Y;  1K8A Y;  1M1K Y;  3I56 X;  1K9M Y;  3CCM X;  3G6E X;  3CME X;  1VQ5 X;  3CCV X;  1Q82 Y;  1Q86 Y;  1VQN X;  3CCS X;  3I55 X;  3G4S X;  3CD6 X;  1K73 Y;  3CMA X;  2QEX X;  3CC4 X;  1VQL X;  3CC7 X;  1KD1 Y;  2OTL X;  3CC2 X;  1JJ2 W;  1YJ9 X;  1VQP X; 
#chains in the Genus database with same CATH topology
 3CPW W;  3CCQ X;  1YIT X;  2OTJ X;  1VQ6 X;  1W2B W;  1VQK X;  1VQ9 X;  1YIJ X;  1S72 X;  3G71 X;  3CCU X;  1QVF W;  3CCJ X;  3CCL X;  3OW2 W;  1VQO X;  1YHQ X;  1NJI Y;  1VQ4 X;  1Q7Y Y;  1YI2 X;  3CXC W;  3CCR X;  1KC8 Y;  1VQ7 X;  1QVG W;  1YJN X;  1M90 Y;  1VQ8 X;  1KQS W;  1YJW X;  1VQM X;  2QA4 X;  1N8R Y;  3CCE X;  1Q81 Y;  1K8A Y;  1M1K Y;  3I56 X;  1K9M Y;  3CCM X;  3G6E X;  3CME X;  1VQ5 X;  3CCV X;  1Q82 Y;  1Q86 Y;  1VQN X;  3CCS X;  3I55 X;  3G4S X;  3CD6 X;  1K73 Y;  3CMA X;  2QEX X;  3CC4 X;  1VQL X;  3CC7 X;  1KD1 Y;  2OTL X;  3CC2 X;  1JJ2 W;  1YJ9 X;  1VQP X; 
#chains in the Genus database with same CATH homology
 3CPW W;  3CCQ X;  1YIT X;  2OTJ X;  1VQ6 X;  1W2B W;  1VQK X;  1VQ9 X;  1YIJ X;  1S72 X;  3G71 X;  3CCU X;  1QVF W;  3CCJ X;  3CCL X;  3OW2 W;  1VQO X;  1YHQ X;  1NJI Y;  1VQ4 X;  1Q7Y Y;  1YI2 X;  3CXC W;  3CCR X;  1KC8 Y;  1VQ7 X;  1QVG W;  1YJN X;  1M90 Y;  1VQ8 X;  1KQS W;  1YJW X;  1VQM X;  2QA4 X;  1N8R Y;  3CCE X;  1Q81 Y;  1K8A Y;  1M1K Y;  3I56 X;  1K9M Y;  3CCM X;  3G6E X;  3CME X;  1VQ5 X;  3CCV X;  1Q82 Y;  1Q86 Y;  1VQN X;  3CCS X;  3I55 X;  3G4S X;  3CD6 X;  1K73 Y;  3CMA X;  2QEX X;  3CC4 X;  1VQL X;  3CC7 X;  1KD1 Y;  2OTL X;  3CC2 X;  1JJ2 W;  1YJ9 X;  1VQP X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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