1Z0QA

Aqueous solution structure of the alzheimer's disease abeta peptide (1-42)
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
42
structure length
42
Chain Sequence
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The alpha-to-beta Conformational Transition of Alzheimer's Abeta-(1-42) Peptide in Aqueous Media is Reversible: A Step by Step Conformational Analysis Suggests the Location of beta Conformation Seeding
pubmed doi rcsb
molecule keywords Alzheimer's disease amyloid
molecule tags Protein binding
total genus 7
structure length 42
sequence length 42
ec nomenclature
pdb deposition date 2005-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03494 Beta-APP Beta-amyloid peptide (beta-APP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.230.10 Few Secondary Structures Irregular Amyloid A4 Amyloidogenic glycoprotein, amyloid-beta peptide 1z0qA00
1Z0QA 1BA4A 1IYTA 1AMLA
chains in the Genus database with same CATH superfamily
1Z0QA 1BA4A 1IYTA 1AMLA
chains in the Genus database with same CATH topology
1Z0QA 1BA4A 1IYTA 1AMLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Z0Q A;  1BA4 A;  1IYT A;  1AML A; 
#chains in the Genus database with same CATH topology
 1Z0Q A;  1BA4 A;  1IYT A;  1AML A; 
#chains in the Genus database with same CATH homology
 1Z0Q A;  1BA4 A;  1IYT A;  1AML A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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