1L8CA

Structural basis for hif-1alpha/cbp recognition in the cellular hypoxic response
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
95
structure length
95
Chain Sequence
ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response.
pubmed doi rcsb
molecule tags Gene regulation
source organism Mus musculus
molecule keywords CREB-binding protein
total genus 29
structure length 95
sequence length 95
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2002-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02135 zf-TAZ TAZ zinc finger
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1020.10 Mainly Alpha Up-down Bundle CREB-binding Protein; Chain A TAZ domain 1l8cA00
3T92A 2K8FA 1R8UB 2KA6A 3P57P 2LWWA 2MH0B 2KJEA 2MZDA 1F81A 1L3EB 1P4QB 5HP0A 2KA4A 3IO2A 1U2NA 1L8CA
chains in the Genus database with same CATH superfamily
3T92A 2K8FA 1R8UB 2KA6A 3P57P 2LWWA 2MH0B 2KJEA 2MZDA 1F81A 1L3EB 1P4QB 5HP0A 2KA4A 3IO2A 1U2NA 1L8CA
chains in the Genus database with same CATH topology
3T92A 2K8FA 1R8UB 2KA6A 3P57P 2LWWA 2MH0B 2KJEA 2MZDA 1F81A 1L3EB 1P4QB 5HP0A 2KA4A 3IO2A 1U2NA 1L8CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T92 A;  2K8F A;  1R8U B;  2KA6 A;  3P57 P;  2LWW A;  2MH0 B;  2KJE A;  2MZD A;  1F81 A;  1L3E B;  1P4Q B;  5HP0 A;  2KA4 A;  3IO2 A;  1U2N A;  1L8C A; 
#chains in the Genus database with same CATH topology
 3T92 A;  2K8F A;  1R8U B;  2KA6 A;  3P57 P;  2LWW A;  2MH0 B;  2KJE A;  2MZD A;  1F81 A;  1L3E B;  1P4Q B;  5HP0 A;  2KA4 A;  3IO2 A;  1U2N A;  1L8C A; 
#chains in the Genus database with same CATH homology
 3T92 A;  2K8F A;  1R8U B;  2KA6 A;  3P57 P;  2LWW A;  2MH0 B;  2KJE A;  2MZD A;  1F81 A;  1L3E B;  1P4Q B;  5HP0 A;  2KA4 A;  3IO2 A;  1U2N A;  1L8C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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