2CJEA

The crystal structure of a complex of leishmania major dutpase with substrate analogue dupnhp
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
258
structure length
258
Chain Sequence
NIPGAILHSLAELQDGLNAMIDPSWRAVRSLDNWALAITMESTELLDSYPWKWWKNLNATPDLANVRIELVDIFHFSLSGAMQMRSTPDDEIPAASLKPLKEVMTTFLPAKECTSDPYGFVFFPLTDTQNAIASFRNIIQLANAYRFDVIIECIIYAAEDLGFNLVAYYIAKHTLNCIRQLSGYKDGSYVKVNNGVEDNSLLHNCIKDVSLDEVLDADKYVQAWNSIMANVYEAFQIKESDRKDAERWFALAKENRLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine.
pubmed doi rcsb
molecule tags Hydrolase
source organism Leishmania major
molecule keywords DUTPASE
total genus 92
structure length 258
sequence length 258
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2006-03-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08761 dUTPase_2 dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1670.10 Mainly Alpha Up-down Bundle all-alpha NTP pyrophosphatase Type II deoxyuridine triphosphatase 2cjeA02
1.20.1680.10 Mainly Alpha Up-down Bundle all-alpha NTP pyrophosphatases Type II deoxyuridine triphosphatase 2cjeA01
2YB0A 2YAYA 2YAZA 2CJEA 1OGLA 1OGKA 4DK2A
chains in the Genus database with same CATH superfamily
2YB0A 2YAYA 2YAZA 2CJEA 1OGLA 1OGKA 4DK2A
chains in the Genus database with same CATH topology
4DL8A 4DLCA 4DKBA 1W2YA 2YB0A 2YAYA 2YAZA 2CICA 2CJEA 1OGLA 4DK4A 1OGKA 4DK2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YB0 A;  2YAY A;  2YAZ A;  2CJE A;  1OGL A;  1OGK A;  4DK2 A; 
#chains in the Genus database with same CATH topology
 2YB0 A;  2YAY A;  2YAZ A;  2CJE A;  1OGL A;  1OGK A;  4DK2 A; 
#chains in the Genus database with same CATH homology
 4DL8 A;  4DLC A;  4DKB A;  1W2Y A;  2YB0 A;  2YAY A;  2YAZ A;  2CIC A;  2CJE A;  1OGL A;  4DK4 A;  1OGK A;  4DK2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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