2YAYA

The crystal structure of leishmania major dutpase in complex with substrate analogue dupnpp
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
257
structure length
257
Chain Sequence
NIPGAILHSLAELQDGLNAMIDPSWRAVRSLDNWALAITMESTELLDSYPWKWWKNLNATPDLANVRIELVDIFHFSLSGAMQMRSTPDDEIPAASLKPLKEVMTTFLPAKECTSDPYGFVFFPLTDTQNAIASFRNIIQLANAYRFDVIIECIIYAAEDLGFNLVAYYIAKHTLNCIRQLSGYKDGSYVKVNNGVEDNSLLHNCIKDVSLDEVLDADKYVQAWNSIMANVYEAFQIKESDRKDAERWFALAKENRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords DUTPASE
publication title The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine.
pubmed doi rcsb
source organism Leishmania major
total genus 95
structure length 257
sequence length 257
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2011-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08761 dUTPase_2 dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1670.10 Mainly Alpha Up-down Bundle all-alpha NTP pyrophosphatase Type II deoxyuridine triphosphatase 2yayA02
1.20.1680.10 Mainly Alpha Up-down Bundle all-alpha NTP pyrophosphatases Type II deoxyuridine triphosphatase 2yayA01
2YAZA 1OGKA 4DK2A 2YAYA 1OGLA 2YB0A 2CJEA
chains in the Genus database with same CATH superfamily
2YAZA 1OGKA 4DK2A 2YAYA 1OGLA 2YB0A 2CJEA
chains in the Genus database with same CATH topology
4DL8A 4DK4A 2CICA 2YAZA 1OGKA 4DK2A 2YAYA 1OGLA 1W2YA 4DKBA 4DLCA 2YB0A 2CJEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YAZ A;  1OGK A;  4DK2 A;  2YAY A;  1OGL A;  2YB0 A;  2CJE A; 
#chains in the Genus database with same CATH topology
 2YAZ A;  1OGK A;  4DK2 A;  2YAY A;  1OGL A;  2YB0 A;  2CJE A; 
#chains in the Genus database with same CATH homology
 4DL8 A;  4DK4 A;  2CIC A;  2YAZ A;  1OGK A;  4DK2 A;  2YAY A;  1OGL A;  1W2Y A;  4DKB A;  4DLC A;  2YB0 A;  2CJE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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