2CJEA

The crystal structure of a complex of leishmania major dutpase with substrate analogue dupnhp
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
258
structure length
258
Chain Sequence
NIPGAILHSLAELQDGLNAMIDPSWRAVRSLDNWALAITMESTELLDSYPWKWWKNLNATPDLANVRIELVDIFHFSLSGAMQMRSTPDDEIPAASLKPLKEVMTTFLPAKECTSDPYGFVFFPLTDTQNAIASFRNIIQLANAYRFDVIIECIIYAAEDLGFNLVAYYIAKHTLNCIRQLSGYKDGSYVKVNNGVEDNSLLHNCIKDVSLDEVLDADKYVQAWNSIMANVYEAFQIKESDRKDAERWFALAKENRLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords DUTPASE
publication title The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine.
pubmed doi rcsb
source organism Leishmania major
total genus 92
structure length 258
sequence length 258
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2006-03-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08761 dUTPase_2 dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1670.10 Mainly Alpha Up-down Bundle all-alpha NTP pyrophosphatase Type II deoxyuridine triphosphatase 2cjeA02
1.20.1680.10 Mainly Alpha Up-down Bundle all-alpha NTP pyrophosphatases Type II deoxyuridine triphosphatase 2cjeA01
4DK2A 1OGKA 2YB0A 2YAZA 2CJEA 1OGLA 2YAYA
chains in the Genus database with same CATH superfamily
4DK2A 1OGKA 2YB0A 2YAZA 2CJEA 1OGLA 2YAYA
chains in the Genus database with same CATH topology
4DLCA 4DK2A 4DKBA 1OGKA 2CICA 2YB0A 4DK4A 2YAZA 1W2YA 2CJEA 1OGLA 2YAYA 4DL8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DK2 A;  1OGK A;  2YB0 A;  2YAZ A;  2CJE A;  1OGL A;  2YAY A; 
#chains in the Genus database with same CATH topology
 4DK2 A;  1OGK A;  2YB0 A;  2YAZ A;  2CJE A;  1OGL A;  2YAY A; 
#chains in the Genus database with same CATH homology
 4DLC A;  4DK2 A;  4DKB A;  1OGK A;  2CIC A;  2YB0 A;  4DK4 A;  2YAZ A;  1W2Y A;  2CJE A;  1OGL A;  2YAY A;  4DL8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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