2K8FA

Structural basis for the regulation of p53 function by p300
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
90
structure length
90
Chain Sequence
ATQSPGDSRRLSIQRAIQSLVHAAQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALAAYHAKHCQENKCPVPFCLNIKQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation.
pubmed doi rcsb
molecule tags Transferase/transcription
source organism Homo sapiens
molecule keywords Histone acetyltransferase p300
total genus 26
structure length 90
sequence length 90
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2008-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02135 zf-TAZ TAZ zinc finger
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1020.10 Mainly Alpha Up-down Bundle CREB-binding Protein; Chain A TAZ domain 2k8fA00
5HP0A 2MH0B 1P4QB 2KA6A 1F81A 3T92A 3IO2A 2LWWA 1U2NA 2MZDA 3P57P 2K8FA 1L8CA 2KJEA 2KA4A 1L3EB 1R8UB
chains in the Genus database with same CATH superfamily
5HP0A 2MH0B 1P4QB 2KA6A 1F81A 3T92A 3IO2A 2LWWA 1U2NA 2MZDA 3P57P 2K8FA 1L8CA 2KJEA 2KA4A 1L3EB 1R8UB
chains in the Genus database with same CATH topology
5HP0A 2MH0B 1P4QB 2KA6A 1F81A 3T92A 3IO2A 2LWWA 1U2NA 2MZDA 3P57P 2K8FA 1L8CA 2KJEA 2KA4A 1L3EB 1R8UB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HP0 A;  2MH0 B;  1P4Q B;  2KA6 A;  1F81 A;  3T92 A;  3IO2 A;  2LWW A;  1U2N A;  2MZD A;  3P57 P;  2K8F A;  1L8C A;  2KJE A;  2KA4 A;  1L3E B;  1R8U B; 
#chains in the Genus database with same CATH topology
 5HP0 A;  2MH0 B;  1P4Q B;  2KA6 A;  1F81 A;  3T92 A;  3IO2 A;  2LWW A;  1U2N A;  2MZD A;  3P57 P;  2K8F A;  1L8C A;  2KJE A;  2KA4 A;  1L3E B;  1R8U B; 
#chains in the Genus database with same CATH homology
 5HP0 A;  2MH0 B;  1P4Q B;  2KA6 A;  1F81 A;  3T92 A;  3IO2 A;  2LWW A;  1U2N A;  2MZD A;  3P57 P;  2K8F A;  1L8C A;  2KJE A;  2KA4 A;  1L3E B;  1R8U B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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