2KU5A

Mouse prion protein (121-231) with mutation d167s
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
113
structure length
113
Chain Sequence
SVVGGLGGYMLGSAMSRPMIHFGNDWEDRYYRENMYRYPNQVYYRPVSQYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCVTQYQKESQAYYDGRRSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Horse prion protein NMR structure and comparisons with related variants of the mouse prion protein.
pubmed doi rcsb
molecule tags Unknown function
source organism Mus musculus
molecule keywords Major prion protein
total genus 31
structure length 113
sequence length 113
ec nomenclature
pdb deposition date 2010-02-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.790.10 Mainly Alpha Orthogonal Bundle Major Prion Protein Prion/Doppel protein, beta-ribbon domain 2ku5A00
1DX1A 1TQBA 1Y2SA 1FO7A 3HERA 1XYXA 3HAFA 1XYWA 2W9EA 1QM1A 1U5LA 1B10A 3HESA 2L1HA 2L40A 2K56A 1Y15A 1Y16A 1I17A 2KFMA 1QM2A 2LSBA 2KFLA 2KU4A 2MV8A 3HJXA 3HAKA 1HJNA 1UW3A 2K5OA 1QLXA 3O79A 1E1GA 1QM0A 1E1PA 1XYQA 2FJ3A 2LH8A 3HJ5A 1TPXA 1LG4A 2L1KA 1H0LA 1E1UA 4DGIA 1E1WA 1E1SA 2LEJA 1HJMA 1XYUA 1DWZA 3HEQA 1QLZA 1AG2A 2JOMA 2JOHA 2L39A 2K1DA 1U3MA 2KUNA 2L1EA 1FKCA 1XYJA 1DWYA 1QM3A 2KTMA 2LFTA 2KU6A 2KU5A 1I4MA 1XYKA 1DX0A 1TQCA 2KFOA 1XU0A 1E1JA 2L1DA
chains in the Genus database with same CATH superfamily
1DX1A 1TQBA 1Y2SA 1FO7A 3HERA 1XYXA 3HAFA 1XYWA 2W9EA 1QM1A 1U5LA 1B10A 3HESA 2MDZA 2L1HA 2L40A 2LL0A 2K56A 1Y15A 1Y16A 1I17A 2KFMA 1QM2A 2LSBA 2KFLA 2KU4A 2MV8A 3HJXA 3HAKA 1HJNA 1UW3A 2K5OA 1QLXA 3O79A 1E1GA 1QM0A 1E1PA 1XYQA 2FJ3A 2LH8A 3HJ5A 1TPXA 1LG4A 2L1KA 1H0LA 1E1UA 4DGIA 1E1WA 1E1SA 2LEJA 1HJMA 1XYUA 1DWZA 3HEQA 1QLZA 1AG2A 2JOMA 2JOHA 2L39A 2K1DA 1U3MA 2KUNA 2L1EA 1FKCA 1XYJA 1DWYA 1QM3A 2KTMA 2LFTA 2KU6A 2KU5A 1I4MA 1XYKA 1DX0A 1TQCA 2KFOA 1XU0A 1E1JA 2KZCA 2L1DA
chains in the Genus database with same CATH topology
1DX1A 1TQBA 1Y2SA 1FO7A 3HERA 1XYXA 3HAFA 1XYWA 2W9EA 1QM1A 1U5LA 1B10A 3HESA 2L1HA 2L40A 2K56A 1Y15A 1Y16A 1I17A 2KFMA 1QM2A 2LSBA 2KFLA 2KU4A 2MV8A 3HJXA 3HAKA 1HJNA 1UW3A 2K5OA 1QLXA 3O79A 1E1GA 1QM0A 1E1PA 1XYQA 2FJ3A 2LH8A 3HJ5A 1TPXA 1LG4A 2L1KA 1H0LA 1E1UA 4DGIA 1E1WA 1E1SA 2LEJA 1HJMA 1XYUA 1DWZA 3HEQA 1QLZA 1AG2A 2JOMA 2JOHA 2L39A 2K1DA 1U3MA 2KUNA 2L1EA 1FKCA 1XYJA 1DWYA 1QM3A 2KTMA 2LFTA 2KU6A 2KU5A 1I4MA 1XYKA 1DX0A 1TQCA 2KFOA 1XU0A 1E1JA 2L1DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DX1 A;  1TQB A;  1Y2S A;  1FO7 A;  3HER A;  1XYX A;  3HAF A;  1XYW A;  2W9E A;  1QM1 A;  1U5L A;  1B10 A;  3HES A;  2L1H A;  2L40 A;  2K56 A;  1Y15 A;  1Y16 A;  1I17 A;  2KFM A;  1QM2 A;  2LSB A;  2KFL A;  2KU4 A;  2MV8 A;  3HJX A;  3HAK A;  1HJN A;  1UW3 A;  2K5O A;  1QLX A;  3O79 A;  1E1G A;  1QM0 A;  1E1P A;  1XYQ A;  2FJ3 A;  2LH8 A;  3HJ5 A;  1TPX A;  1LG4 A;  2L1K A;  1H0L A;  1E1U A;  4DGI A;  1E1W A;  1E1S A;  2LEJ A;  1HJM A;  1XYU A;  1DWZ A;  3HEQ A;  1QLZ A;  1AG2 A;  2JOM A;  2JOH A;  2L39 A;  2K1D A;  1U3M A;  2KUN A;  2L1E A;  1FKC A;  1XYJ A;  1DWY A;  1QM3 A;  2KTM A;  2LFT A;  2KU6 A;  2KU5 A;  1I4M A;  1XYK A;  1DX0 A;  1TQC A;  2KFO A;  1XU0 A;  1E1J A;  2L1D A; 
#chains in the Genus database with same CATH topology
 1DX1 A;  1TQB A;  1Y2S A;  1FO7 A;  3HER A;  1XYX A;  3HAF A;  1XYW A;  2W9E A;  1QM1 A;  1U5L A;  1B10 A;  3HES A;  2MDZ A;  2L1H A;  2L40 A;  2LL0 A;  2K56 A;  1Y15 A;  1Y16 A;  1I17 A;  2KFM A;  1QM2 A;  2LSB A;  2KFL A;  2KU4 A;  2MV8 A;  3HJX A;  3HAK A;  1HJN A;  1UW3 A;  2K5O A;  1QLX A;  3O79 A;  1E1G A;  1QM0 A;  1E1P A;  1XYQ A;  2FJ3 A;  2LH8 A;  3HJ5 A;  1TPX A;  1LG4 A;  2L1K A;  1H0L A;  1E1U A;  4DGI A;  1E1W A;  1E1S A;  2LEJ A;  1HJM A;  1XYU A;  1DWZ A;  3HEQ A;  1QLZ A;  1AG2 A;  2JOM A;  2JOH A;  2L39 A;  2K1D A;  1U3M A;  2KUN A;  2L1E A;  1FKC A;  1XYJ A;  1DWY A;  1QM3 A;  2KTM A;  2LFT A;  2KU6 A;  2KU5 A;  1I4M A;  1XYK A;  1DX0 A;  1TQC A;  2KFO A;  1XU0 A;  1E1J A;  2KZC A;  2L1D A; 
#chains in the Genus database with same CATH homology
 1DX1 A;  1TQB A;  1Y2S A;  1FO7 A;  3HER A;  1XYX A;  3HAF A;  1XYW A;  2W9E A;  1QM1 A;  1U5L A;  1B10 A;  3HES A;  2L1H A;  2L40 A;  2K56 A;  1Y15 A;  1Y16 A;  1I17 A;  2KFM A;  1QM2 A;  2LSB A;  2KFL A;  2KU4 A;  2MV8 A;  3HJX A;  3HAK A;  1HJN A;  1UW3 A;  2K5O A;  1QLX A;  3O79 A;  1E1G A;  1QM0 A;  1E1P A;  1XYQ A;  2FJ3 A;  2LH8 A;  3HJ5 A;  1TPX A;  1LG4 A;  2L1K A;  1H0L A;  1E1U A;  4DGI A;  1E1W A;  1E1S A;  2LEJ A;  1HJM A;  1XYU A;  1DWZ A;  3HEQ A;  1QLZ A;  1AG2 A;  2JOM A;  2JOH A;  2L39 A;  2K1D A;  1U3M A;  2KUN A;  2L1E A;  1FKC A;  1XYJ A;  1DWY A;  1QM3 A;  2KTM A;  2LFT A;  2KU6 A;  2KU5 A;  1I4M A;  1XYK A;  1DX0 A;  1TQC A;  2KFO A;  1XU0 A;  1E1J A;  2L1D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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