2L1EA

Mouse prion protein (121-231) containing the substitution f175a
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
114
structure length
114
Chain Sequence
GSVVGGLGGYMLGSAMSRPMIHFGNDWEDRYYRENMYRYPNQVYYRPVDQYSNQNNAVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCVTQYQKESQAYYDGRRSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Prion Protein mPrP[F175A](121-231): Structure and Stability in Solution.
pubmed doi rcsb
molecule tags Membrane protein
source organism Mus musculus
molecule keywords Major prion protein
total genus 32
structure length 114
sequence length 114
ec nomenclature
pdb deposition date 2010-07-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.790.10 Mainly Alpha Orthogonal Bundle Major Prion Protein Prion/Doppel protein, beta-ribbon domain 2l1eA00
3HEQA 1U3MA 2KFLA 3HJ5A 1XYKA 3HERA 1HJNA 1FO7A 1QM0A 1DWYA 1QM3A 2L40A 3HESA 2FJ3A 2K56A 1DX1A 3O79A 2L1EA 1E1PA 2LH8A 1U5LA 3HJXA 1XYJA 2L1HA 1H0LA 1XYWA 2KU6A 1QLXA 3HAFA 1TQBA 2LSBA 2KTMA 1E1WA 1I17A 2KFOA 2L1DA 2KUNA 1I4MA 2L39A 1QLZA 1FKCA 2JOHA 1XYUA 2KU4A 1E1SA 2MV8A 2LEJA 1UW3A 1B10A 3HAKA 1DX0A 1AG2A 2K5OA 1XU0A 2L1KA 1TQCA 2LFTA 1E1UA 2KFMA 1E1GA 4DGIA 2KU5A 1Y16A 1TPXA 1HJMA 2K1DA 1DWZA 1XYQA 2W9EA 1QM2A 1LG4A 1E1JA 1QM1A 2JOMA 1Y2SA 1Y15A 1XYXA
chains in the Genus database with same CATH superfamily
3HEQA 1U3MA 2KFLA 3HJ5A 1XYKA 3HERA 1HJNA 1FO7A 1QM0A 1DWYA 1QM3A 2L40A 3HESA 2FJ3A 2K56A 1DX1A 3O79A 2L1EA 1E1PA 2LH8A 2LL0A 1U5LA 2KZCA 3HJXA 1XYJA 2L1HA 1H0LA 1XYWA 2KU6A 1QLXA 3HAFA 1TQBA 2LSBA 2KTMA 1E1WA 1I17A 2KFOA 2L1DA 2KUNA 1I4MA 2L39A 1QLZA 1FKCA 2JOHA 1XYUA 2KU4A 1E1SA 2MV8A 2LEJA 1UW3A 1B10A 3HAKA 2MDZA 1DX0A 1AG2A 2K5OA 1XU0A 2L1KA 1TQCA 2LFTA 1E1UA 2KFMA 1E1GA 4DGIA 2KU5A 1Y16A 1TPXA 1HJMA 2K1DA 1DWZA 1XYQA 2W9EA 1QM2A 1LG4A 1E1JA 1QM1A 2JOMA 1Y2SA 1Y15A 1XYXA
chains in the Genus database with same CATH topology
3HEQA 1U3MA 2KFLA 3HJ5A 1XYKA 3HERA 1HJNA 1FO7A 1QM0A 1DWYA 1QM3A 2L40A 3HESA 2FJ3A 2K56A 1DX1A 3O79A 2L1EA 1E1PA 2LH8A 1U5LA 3HJXA 1XYJA 2L1HA 1H0LA 1XYWA 2KU6A 1QLXA 3HAFA 1TQBA 2LSBA 2KTMA 1E1WA 1I17A 2KFOA 2L1DA 2KUNA 1I4MA 2L39A 1QLZA 1FKCA 2JOHA 1XYUA 2KU4A 1E1SA 2MV8A 2LEJA 1UW3A 1B10A 3HAKA 1DX0A 1AG2A 2K5OA 1XU0A 2L1KA 1TQCA 2LFTA 1E1UA 2KFMA 1E1GA 4DGIA 2KU5A 1Y16A 1TPXA 1HJMA 2K1DA 1DWZA 1XYQA 2W9EA 1QM2A 1LG4A 1E1JA 1QM1A 2JOMA 1Y2SA 1Y15A 1XYXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HEQ A;  1U3M A;  2KFL A;  3HJ5 A;  1XYK A;  3HER A;  1HJN A;  1FO7 A;  1QM0 A;  1DWY A;  1QM3 A;  2L40 A;  3HES A;  2FJ3 A;  2K56 A;  1DX1 A;  3O79 A;  2L1E A;  1E1P A;  2LH8 A;  1U5L A;  3HJX A;  1XYJ A;  2L1H A;  1H0L A;  1XYW A;  2KU6 A;  1QLX A;  3HAF A;  1TQB A;  2LSB A;  2KTM A;  1E1W A;  1I17 A;  2KFO A;  2L1D A;  2KUN A;  1I4M A;  2L39 A;  1QLZ A;  1FKC A;  2JOH A;  1XYU A;  2KU4 A;  1E1S A;  2MV8 A;  2LEJ A;  1UW3 A;  1B10 A;  3HAK A;  1DX0 A;  1AG2 A;  2K5O A;  1XU0 A;  2L1K A;  1TQC A;  2LFT A;  1E1U A;  2KFM A;  1E1G A;  4DGI A;  2KU5 A;  1Y16 A;  1TPX A;  1HJM A;  2K1D A;  1DWZ A;  1XYQ A;  2W9E A;  1QM2 A;  1LG4 A;  1E1J A;  1QM1 A;  2JOM A;  1Y2S A;  1Y15 A;  1XYX A; 
#chains in the Genus database with same CATH topology
 3HEQ A;  1U3M A;  2KFL A;  3HJ5 A;  1XYK A;  3HER A;  1HJN A;  1FO7 A;  1QM0 A;  1DWY A;  1QM3 A;  2L40 A;  3HES A;  2FJ3 A;  2K56 A;  1DX1 A;  3O79 A;  2L1E A;  1E1P A;  2LH8 A;  2LL0 A;  1U5L A;  2KZC A;  3HJX A;  1XYJ A;  2L1H A;  1H0L A;  1XYW A;  2KU6 A;  1QLX A;  3HAF A;  1TQB A;  2LSB A;  2KTM A;  1E1W A;  1I17 A;  2KFO A;  2L1D A;  2KUN A;  1I4M A;  2L39 A;  1QLZ A;  1FKC A;  2JOH A;  1XYU A;  2KU4 A;  1E1S A;  2MV8 A;  2LEJ A;  1UW3 A;  1B10 A;  3HAK A;  2MDZ A;  1DX0 A;  1AG2 A;  2K5O A;  1XU0 A;  2L1K A;  1TQC A;  2LFT A;  1E1U A;  2KFM A;  1E1G A;  4DGI A;  2KU5 A;  1Y16 A;  1TPX A;  1HJM A;  2K1D A;  1DWZ A;  1XYQ A;  2W9E A;  1QM2 A;  1LG4 A;  1E1J A;  1QM1 A;  2JOM A;  1Y2S A;  1Y15 A;  1XYX A; 
#chains in the Genus database with same CATH homology
 3HEQ A;  1U3M A;  2KFL A;  3HJ5 A;  1XYK A;  3HER A;  1HJN A;  1FO7 A;  1QM0 A;  1DWY A;  1QM3 A;  2L40 A;  3HES A;  2FJ3 A;  2K56 A;  1DX1 A;  3O79 A;  2L1E A;  1E1P A;  2LH8 A;  1U5L A;  3HJX A;  1XYJ A;  2L1H A;  1H0L A;  1XYW A;  2KU6 A;  1QLX A;  3HAF A;  1TQB A;  2LSB A;  2KTM A;  1E1W A;  1I17 A;  2KFO A;  2L1D A;  2KUN A;  1I4M A;  2L39 A;  1QLZ A;  1FKC A;  2JOH A;  1XYU A;  2KU4 A;  1E1S A;  2MV8 A;  2LEJ A;  1UW3 A;  1B10 A;  3HAK A;  1DX0 A;  1AG2 A;  2K5O A;  1XU0 A;  2L1K A;  1TQC A;  2LFT A;  1E1U A;  2KFM A;  1E1G A;  4DGI A;  2KU5 A;  1Y16 A;  1TPX A;  1HJM A;  2K1D A;  1DWZ A;  1XYQ A;  2W9E A;  1QM2 A;  1LG4 A;  1E1J A;  1QM1 A;  2JOM A;  1Y2S A;  1Y15 A;  1XYX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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