The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
29
|
sequence length |
142
|
structure length |
142
|
Chain Sequence |
GQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYKRESQAYYQRGSS
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism.
pubmed doi rcsb |
| molecule tags |
Membrane protein
|
| source organism |
Homo sapiens
|
| molecule keywords |
Major prion protein
|
| total genus |
29
|
| structure length |
142
|
| sequence length |
142
|
| ec nomenclature | |
| pdb deposition date | 2011-07-14 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Major Prion Protein | Prion/Doppel protein, beta-ribbon domain |
#chains in the Genus database with same CATH superfamily 2KFL A; 2L1K A; 1DWY A; 2KU5 A; 1AG2 A; 2L39 A; 2K5O A; 4DGI A; 3HES A; 1QM3 A; 1B10 A; 1DWZ A; 1TQC A; 1Y2S A; 1QM1 A; 2JOM A; 2FJ3 A; 2L40 A; 2L1D A; 1XYX A; 1DX1 A; 1UW3 A; 1XYK A; 1E1J A; 3HAK A; 1XU0 A; 2LH8 A; 1U5L A; 2W9E A; 2K56 A; 2L1H A; 1I4M A; 1XYJ A; 2KU6 A; 1QLX A; 1H0L A; 1XYQ A; 1E1G A; 1TPX A; 2LSB A; 1FO7 A; 2LEJ A; 1LG4 A; 1E1U A; 2KU4 A; 3O79 A; 1XYU A; 2KFM A; 2KUN A; 2LFT A; 1E1W A; 1Y16 A; 2MV8 A; 1QM2 A; 1HJN A; 3HJ5 A; 3HAF A; 2JOH A; 1DX0 A; 1FKC A; 3HER A; 1E1S A; 3HJX A; 2KTM A; 1TQB A; 1QLZ A; 1E1P A; 3HEQ A; 1XYW A; 2K1D A; 1U3M A; 2L1E A; 1HJM A; 1I17 A; 1Y15 A; 2KFO A; 1QM0 A; #chains in the Genus database with same CATH topology 2KFL A; 2L1K A; 1DWY A; 2KU5 A; 1AG2 A; 2L39 A; 2K5O A; 4DGI A; 3HES A; 1QM3 A; 1B10 A; 1DWZ A; 2KZC A; 1TQC A; 1Y2S A; 1QM1 A; 2JOM A; 2FJ3 A; 2L40 A; 2L1D A; 1XYX A; 1DX1 A; 1UW3 A; 1XYK A; 1E1J A; 3HAK A; 1XU0 A; 2LH8 A; 1U5L A; 2W9E A; 2K56 A; 2L1H A; 1I4M A; 1XYJ A; 2KU6 A; 1QLX A; 1H0L A; 1XYQ A; 1E1G A; 1TPX A; 2LSB A; 1FO7 A; 2LEJ A; 1LG4 A; 1E1U A; 2KU4 A; 3O79 A; 1XYU A; 2MDZ A; 2KFM A; 2KUN A; 2LFT A; 1E1W A; 1Y16 A; 2MV8 A; 1QM2 A; 1HJN A; 3HJ5 A; 3HAF A; 2JOH A; 1DX0 A; 1FKC A; 3HER A; 1E1S A; 3HJX A; 2KTM A; 1TQB A; 1QLZ A; 1E1P A; 3HEQ A; 1XYW A; 2K1D A; 1U3M A; 2L1E A; 1HJM A; 1I17 A; 1Y15 A; 2KFO A; 2LL0 A; 1QM0 A; #chains in the Genus database with same CATH homology 2KFL A; 2L1K A; 1DWY A; 2KU5 A; 1AG2 A; 2L39 A; 2K5O A; 4DGI A; 3HES A; 1QM3 A; 1B10 A; 1DWZ A; 1TQC A; 1Y2S A; 1QM1 A; 2JOM A; 2FJ3 A; 2L40 A; 2L1D A; 1XYX A; 1DX1 A; 1UW3 A; 1XYK A; 1E1J A; 3HAK A; 1XU0 A; 2LH8 A; 1U5L A; 2W9E A; 2K56 A; 2L1H A; 1I4M A; 1XYJ A; 2KU6 A; 1QLX A; 1H0L A; 1XYQ A; 1E1G A; 1TPX A; 2LSB A; 1FO7 A; 2LEJ A; 1LG4 A; 1E1U A; 2KU4 A; 3O79 A; 1XYU A; 2KFM A; 2KUN A; 2LFT A; 1E1W A; 1Y16 A; 2MV8 A; 1QM2 A; 1HJN A; 3HJ5 A; 3HAF A; 2JOH A; 1DX0 A; 1FKC A; 3HER A; 1E1S A; 3HJX A; 2KTM A; 1TQB A; 1QLZ A; 1E1P A; 3HEQ A; 1XYW A; 2K1D A; 1U3M A; 2L1E A; 1HJM A; 1I17 A; 1Y15 A; 2KFO A; 1QM0 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
