2LWLA

Structural basis for the interaction of human β-defensin 6 and its putative chemokine receptor ccr2 and breast cancer microvesicles
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
45
structure length
45
Chain Sequence
FFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPSGSIID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Interaction of Human beta-Defensin 6 and Its Putative Chemokine Receptor CCR2 and Breast Cancer Microvesicles.
pubmed doi rcsb
molecule tags Antimicrobial protein
source organism Homo sapiens
molecule keywords Beta-defensin 106
total genus 9
structure length 45
sequence length 45
ec nomenclature
pdb deposition date 2012-08-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13841 Defensin_beta_2 Beta defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.360.10 Alpha Beta Roll Antimicrobial Peptide, Beta-defensin 2; Chain A Antimicrobial Peptide, Beta-defensin 2; Chain A 2lwlA00
1FQQA 1KJ6A 1FD3A 2LXOA 2LWLA 1FD4A
chains in the Genus database with same CATH superfamily
3MHDD 1FQQA 2MJKA 1KJ6A 1FD3A 3QD6R 2LXOA 3MI8D 4E4DR 2LWLA 1FD4A 2UWIA
chains in the Genus database with same CATH topology
3MHDD 1FQQA 2MJKA 1KJ6A 1FD3A 3QD6R 2LXOA 3MI8D 4E4DR 2LWLA 1FD4A 2UWIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FQQ A;  1KJ6 A;  1FD3 A;  2LXO A;  2LWL A;  1FD4 A; 
#chains in the Genus database with same CATH topology
 3MHD D;  1FQQ A;  2MJK A;  1KJ6 A;  1FD3 A;  3QD6 R;  2LXO A;  3MI8 D;  4E4D R;  2LWL A;  1FD4 A;  2UWI A; 
#chains in the Genus database with same CATH homology
 3MHD D;  1FQQ A;  2MJK A;  1KJ6 A;  1FD3 A;  3QD6 R;  2LXO A;  3MI8 D;  4E4D R;  2LWL A;  1FD4 A;  2UWI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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