2PVAA

Oxidized penicillin v acylase from b. sphaericus
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
341
structure length
331
Chain Sequence
SSLSIRTTDDKSLFARTMDFTMEPDSKVIIVPRNYGIRLLEKENVVINNSYAFVGMGSTDITSPVLYDGVNEKGLMGAMLYYATFATYADEPKKGTTGINPVYVISQVLGNCVTVDDVIEKLTSYTLLNEANIILGFAPPLHYTFTDASGESIVIEPDKTGITIHRKTIGVMTNSPGYEWHQTNLRAYIGVTPNPPQDIMMGDLDLTPFGQGAGGLGLPGDFTPSARFLRVAYWKKYTEKAKNETEGVTNLFHILSSVNIPKGVVLTNEGKTDYTIYTSAMCAQSKNYYFKLYDNSRISAVSLMAENLNSQDLITFEWDRKQDIKQLNQVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
publication title Penicillin V acylase crystal structure reveals new Ntn-hydrolase family members.
pubmed doi rcsb
molecule keywords PENICILLIN V ACYLASE
total genus 96
structure length 331
sequence length 341
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.11: Penicillin amidase.
pdb deposition date 1998-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02275 CBAH Linear amide C-N hydrolases, choloylglycine hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.60.10 Alpha Beta 4-Layer Sandwich Penicillin V Acylase; Chain A Penicillin V Acylase; Chain A 2pvaA00
2X1CA 2X1EA 2RLCA 2RG2A 2X1DA 2BJGA 3MJIA 2PVAA 2HF0A 2OQCA 5HKEA 3GVZA 4WL2A 2BJFA 3HBCA 2HEZA 2Z71A 3PVAA 4WL3A 2QUYA 2RF8A 2IWMA
chains in the Genus database with same CATH superfamily
2X1CA 2X1EA 2RLCA 2RG2A 2X1DA 2BJGA 3FBXA 3MJIA 2PVAA 2HF0A 2OQCA 5HKEA 3FGRB 4BWCB 3GVZA 4WL2A 2BJFA 3HBCA 2HEZA 2Z71A 3PVAA 4WL3A 2QUYA 2RF8A 2IWMA 3FGWA 3FGTB
chains in the Genus database with same CATH topology
2X1CA 2X1EA 2RLCA 2RG2A 2X1DA 2BJGA 3FBXA 3MJIA 2PVAA 2HF0A 2OQCA 5HKEA 3FGRB 4BWCB 3GVZA 4WL2A 2BJFA 3HBCA 2HEZA 2Z71A 3PVAA 4WL3A 2QUYA 2RF8A 2IWMA 3FGWA 3FGTB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X1C A;  2X1E A;  2RLC A;  2RG2 A;  2X1D A;  2BJG A;  3MJI A;  2PVA A;  2HF0 A;  2OQC A;  5HKE A;  3GVZ A;  4WL2 A;  2BJF A;  3HBC A;  2HEZ A;  2Z71 A;  3PVA A;  4WL3 A;  2QUY A;  2RF8 A;  2IWM A; 
#chains in the Genus database with same CATH topology
 2X1C A;  2X1E A;  2RLC A;  2RG2 A;  2X1D A;  2BJG A;  3FBX A;  3MJI A;  2PVA A;  2HF0 A;  2OQC A;  5HKE A;  3FGR B;  4BWC B;  3GVZ A;  4WL2 A;  2BJF A;  3HBC A;  2HEZ A;  2Z71 A;  3PVA A;  4WL3 A;  2QUY A;  2RF8 A;  2IWM A;  3FGW A;  3FGT B; 
#chains in the Genus database with same CATH homology
 2X1C A;  2X1E A;  2RLC A;  2RG2 A;  2X1D A;  2BJG A;  3FBX A;  3MJI A;  2PVA A;  2HF0 A;  2OQC A;  5HKE A;  3FGR B;  4BWC B;  3GVZ A;  4WL2 A;  2BJF A;  3HBC A;  2HEZ A;  2Z71 A;  3PVA A;  4WL3 A;  2QUY A;  2RF8 A;  2IWM A;  3FGW A;  3FGT B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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