2XAVA

Ribonucleotide reductase y731no2y and y730f modified r1 subunit of e. coli
Total Genus 278
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
278
sequence length
734
structure length
727
Chain Sequence
NLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLFQNTRDG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
source organism Escherichia coli k-12
publication title Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
pubmed doi rcsb
molecule keywords RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA
total genus 278
structure length 727
sequence length 734
chains with identical sequence B, C
ec nomenclature ec 1.17.4.1: Ribonucleoside-diphosphate reductase.
pdb deposition date 2010-03-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00317 Ribonuc_red_lgN Ribonucleotide reductase, all-alpha domain
A PF02867 Ribonuc_red_lgC Ribonucleotide reductase, barrel domain
A PF03477 ATP-cone ATP cone domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.70.20 Alpha Beta Alpha-Beta Barrel Anaerobic Ribonucleotide-triphosphate Reductase Large Chain Anaerobic Ribonucleotide-triphosphate Reductase Large Chain 2xavA02
2CVXA 1XJGA 4X3VA 1H18A 3S8AA 2X0XA 2YAJA 2EUDA 1RLRA 2CVUA 1H7BA 2XAPA 1PEOA 5CNTA 5CNVA 1L1LA 1H16A 1XJFA 1PEMA 1H7AA 1ZZDA 3O0QA 1QHMA 2PFLA 2CVYA 5R1RA 3HNEA 2XAZA 2ZLGA 3HNFA 1MZOA 2XAVA 1H79A 7R1RA 1PEQA 2CVSA 2XO5A 4R1RA 1XJEA 5CNUA 4MTJA 6R1RA 3HNCA 1H17A 1CM5A 1R1RA 2CVVA 3R1RA 1H78A 1ZYZA 2XAWA 2XAKA 2BQ1E 3TBAA 2ZLFA 2XO4A 1R9DA 1XJMA 2CVWA 5CNSA 1XJNA 2F3OA 3HNDA 3S87A 1HK8A 3S8CA 3PFLA 3O0NA 1XJJA 3RSRA 1R8WA 3S8BA 1PEUA 2Y8NA 2HA9A 2XAYA 3O0OA 2R1RA 1XJKA 2WGHA 4ERMA 3K8TA 2XAXA 3TB9A 2CVTA
chains in the Genus database with same CATH superfamily
2CVXA 5FAYA 1XJGA 4X3VA 1H18A 3S8AA 5FAUA 2X0XA 2YAJA 5A0ZA 2EUDA 1RLRA 2CVUA 1H7BA 2XAPA 1PEOA 5CNTA 5CNVA 1L1LA 5A0UA 1H16A 1XJFA 1PEMA 1H7AA 1ZZDA 3O0QA 1QHMA 2PFLA 2CVYA 5R1RA 3HNEA 2XAZA 2ZLGA 3HNFA 5KDPA 1MZOA 2XAVA 1H79A 5FAWA 7R1RA 1PEQA 2CVSA 2XO5A 4R1RA 1XJEA 5CNUA 4MTJA 6R1RA 3HNCA 1H17A 1CM5A 1R1RA 2CVVA 3R1RA 1H78A 1ZYZA 2XAWA 2XAKA 2BQ1E 3TBAA 2ZLFA 2XO4A 1R9DA 1XJMA 2CVWA 5CNSA 1XJNA 2F3OA 3HNDA 3S87A 1HK8A 3S8CA 3PFLA 3O0NA 1XJJA 3RSRA 1R8WA 3S8BA 1PEUA 5FAVA 2Y8NA 2HA9A 2XAYA 3O0OA 2R1RA 1XJKA 2WGHA 4ERMA 3K8TA 2XAXA 3TB9A 2CVTA
chains in the Genus database with same CATH topology
2CVXA 5FAYA 1XJGA 4X3VA 1H18A 3S8AA 5FAUA 2X0XA 2YAJA 5A0ZA 2EUDA 1RLRA 2CVUA 1H7BA 2XAPA 1PEOA 5CNTA 5CNVA 1L1LA 5A0UA 1H16A 1XJFA 1PEMA 1H7AA 1ZZDA 3O0QA 1QHMA 2PFLA 2CVYA 5R1RA 3HNEA 2XAZA 2ZLGA 3HNFA 5KDPA 1MZOA 2XAVA 1H79A 5FAWA 7R1RA 1PEQA 2CVSA 2XO5A 4R1RA 1XJEA 5CNUA 4MTJA 6R1RA 3HNCA 1H17A 1CM5A 1R1RA 2CVVA 3R1RA 1H78A 1ZYZA 2XAWA 2XAKA 2BQ1E 3TBAA 2ZLFA 2XO4A 1R9DA 1XJMA 2CVWA 5CNSA 1XJNA 2F3OA 3HNDA 3S87A 1HK8A 3S8CA 3PFLA 3O0NA 1XJJA 3RSRA 1R8WA 3S8BA 1PEUA 5FAVA 2Y8NA 2HA9A 2XAYA 3O0OA 2R1RA 1XJKA 2WGHA 4ERMA 3K8TA 2XAXA 3TB9A 2CVTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CVX A;  1XJG A;  4X3V A;  1H18 A;  3S8A A;  2X0X A;  2YAJ A;  2EUD A;  1RLR A;  2CVU A;  1H7B A;  2XAP A;  1PEO A;  5CNT A;  5CNV A;  1L1L A;  1H16 A;  1XJF A;  1PEM A;  1H7A A;  1ZZD A;  3O0Q A;  1QHM A;  2PFL A;  2CVY A;  5R1R A;  3HNE A;  2XAZ A;  2ZLG A;  3HNF A;  1MZO A;  2XAV A;  1H79 A;  7R1R A;  1PEQ A;  2CVS A;  2XO5 A;  4R1R A;  1XJE A;  5CNU A;  4MTJ A;  6R1R A;  3HNC A;  1H17 A;  1CM5 A;  1R1R A;  2CVV A;  3R1R A;  1H78 A;  1ZYZ A;  2XAW A;  2XAK A;  2BQ1 E;  3TBA A;  2ZLF A;  2XO4 A;  1R9D A;  1XJM A;  2CVW A;  5CNS A;  1XJN A;  2F3O A;  3HND A;  3S87 A;  1HK8 A;  3S8C A;  3PFL A;  3O0N A;  1XJJ A;  3RSR A;  1R8W A;  3S8B A;  1PEU A;  2Y8N A;  2HA9 A;  2XAY A;  3O0O A;  2R1R A;  1XJK A;  2WGH A;  4ERM A;  3K8T A;  2XAX A;  3TB9 A;  2CVT A; 
#chains in the Genus database with same CATH topology
 2CVX A;  5FAY A;  1XJG A;  4X3V A;  1H18 A;  3S8A A;  5FAU A;  2X0X A;  2YAJ A;  5A0Z A;  2EUD A;  1RLR A;  2CVU A;  1H7B A;  2XAP A;  1PEO A;  5CNT A;  5CNV A;  1L1L A;  5A0U A;  1H16 A;  1XJF A;  1PEM A;  1H7A A;  1ZZD A;  3O0Q A;  1QHM A;  2PFL A;  2CVY A;  5R1R A;  3HNE A;  2XAZ A;  2ZLG A;  3HNF A;  5KDP A;  1MZO A;  2XAV A;  1H79 A;  5FAW A;  7R1R A;  1PEQ A;  2CVS A;  2XO5 A;  4R1R A;  1XJE A;  5CNU A;  4MTJ A;  6R1R A;  3HNC A;  1H17 A;  1CM5 A;  1R1R A;  2CVV A;  3R1R A;  1H78 A;  1ZYZ A;  2XAW A;  2XAK A;  2BQ1 E;  3TBA A;  2ZLF A;  2XO4 A;  1R9D A;  1XJM A;  2CVW A;  5CNS A;  1XJN A;  2F3O A;  3HND A;  3S87 A;  1HK8 A;  3S8C A;  3PFL A;  3O0N A;  1XJJ A;  3RSR A;  1R8W A;  3S8B A;  1PEU A;  5FAV A;  2Y8N A;  2HA9 A;  2XAY A;  3O0O A;  2R1R A;  1XJK A;  2WGH A;  4ERM A;  3K8T A;  2XAX A;  3TB9 A;  2CVT A; 
#chains in the Genus database with same CATH homology
 2CVX A;  5FAY A;  1XJG A;  4X3V A;  1H18 A;  3S8A A;  5FAU A;  2X0X A;  2YAJ A;  5A0Z A;  2EUD A;  1RLR A;  2CVU A;  1H7B A;  2XAP A;  1PEO A;  5CNT A;  5CNV A;  1L1L A;  5A0U A;  1H16 A;  1XJF A;  1PEM A;  1H7A A;  1ZZD A;  3O0Q A;  1QHM A;  2PFL A;  2CVY A;  5R1R A;  3HNE A;  2XAZ A;  2ZLG A;  3HNF A;  5KDP A;  1MZO A;  2XAV A;  1H79 A;  5FAW A;  7R1R A;  1PEQ A;  2CVS A;  2XO5 A;  4R1R A;  1XJE A;  5CNU A;  4MTJ A;  6R1R A;  3HNC A;  1H17 A;  1CM5 A;  1R1R A;  2CVV A;  3R1R A;  1H78 A;  1ZYZ A;  2XAW A;  2XAK A;  2BQ1 E;  3TBA A;  2ZLF A;  2XO4 A;  1R9D A;  1XJM A;  2CVW A;  5CNS A;  1XJN A;  2F3O A;  3HND A;  3S87 A;  1HK8 A;  3S8C A;  3PFL A;  3O0N A;  1XJJ A;  3RSR A;  1R8W A;  3S8B A;  1PEU A;  5FAV A;  2Y8N A;  2HA9 A;  2XAY A;  3O0O A;  2R1R A;  1XJK A;  2WGH A;  4ERM A;  3K8T A;  2XAX A;  3TB9 A;  2CVT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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