2YAYA

The crystal structure of leishmania major dutpase in complex with substrate analogue dupnpp
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
257
structure length
257
Chain Sequence
NIPGAILHSLAELQDGLNAMIDPSWRAVRSLDNWALAITMESTELLDSYPWKWWKNLNATPDLANVRIELVDIFHFSLSGAMQMRSTPDDEIPAASLKPLKEVMTTFLPAKECTSDPYGFVFFPLTDTQNAIASFRNIIQLANAYRFDVIIECIIYAAEDLGFNLVAYYIAKHTLNCIRQLSGYKDGSYVKVNNGVEDNSLLHNCIKDVSLDEVLDADKYVQAWNSIMANVYEAFQIKESDRKDAERWFALAKENRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine.
pubmed doi rcsb
molecule tags Hydrolase
source organism Leishmania major
molecule keywords DUTPASE
total genus 95
structure length 257
sequence length 257
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2011-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08761 dUTPase_2 dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1670.10 Mainly Alpha Up-down Bundle all-alpha NTP pyrophosphatase Type II deoxyuridine triphosphatase 2yayA02
1.20.1680.10 Mainly Alpha Up-down Bundle all-alpha NTP pyrophosphatases Type II deoxyuridine triphosphatase 2yayA01
1OGKA 2YAYA 2CJEA 2YB0A 4DK2A 2YAZA 1OGLA
chains in the Genus database with same CATH superfamily
1OGKA 2YAYA 2CJEA 2YB0A 4DK2A 2YAZA 1OGLA
chains in the Genus database with same CATH topology
1OGKA 2CJEA 2YAYA 2YB0A 4DK2A 4DK4A 2CICA 4DKBA 4DLCA 1W2YA 4DL8A 2YAZA 1OGLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OGK A;  2YAY A;  2CJE A;  2YB0 A;  4DK2 A;  2YAZ A;  1OGL A; 
#chains in the Genus database with same CATH topology
 1OGK A;  2YAY A;  2CJE A;  2YB0 A;  4DK2 A;  2YAZ A;  1OGL A; 
#chains in the Genus database with same CATH homology
 1OGK A;  2CJE A;  2YAY A;  2YB0 A;  4DK2 A;  4DK4 A;  2CIC A;  4DKB A;  4DLC A;  1W2Y A;  4DL8 A;  2YAZ A;  1OGL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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