3G4SX

Co-crystal structure of tiamulin bound to the large ribosomal subunit
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
82
structure length
82
Chain Sequence
ERVVTIPLRDARAEPNHKRADKAMILIREHLAKHFSVDEDAVRLDPSINEAAWARGRANTPSKIRVRAARFEEEGEAIVEAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule keywords 23S ribosomal RNA
molecule tags Ribosome
total genus 20
structure length 82
sequence length 82
ec nomenclature
pdb deposition date 2009-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01198 Ribosomal_L31e Ribosomal protein L31e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.440.10 Alpha Beta Roll Ribosomal Protein L31e; Chain: W; Ribosomal Protein L31e; Chain: W; 3g4sX00
3CXCW 1VQ8X 1M1KY 1YJWX 2QA4X 1JJ2W 1Q86Y 1KQSW 1VQNX 2OTLX 3G6EX 1N8RY 1QVGW 1VQLX 1W2BW 1M90Y 3G71X 1YJNX 3CCRX 1K8AY 1VQ6X 3CCJX 3CCQX 3G4SX 1VQ9X 1VQ5X 1VQ7X 3CMEX 3CCEX 1S72X 1YIJX 2QEXX 2OTJX 3OW2W 1VQKX 1KD1Y 3CCSX 1YHQX 1VQ4X 3CC2X 3I55X 1K9MY 3CPWW 3CC4X 1QVFW 3CD6X 1KC8Y 3CCVX 1YI2X 1K73Y 1YJ9X 1VQOX 1Q7YY 3CCMX 1Q82Y 1YITX 1VQPX 1VQMX 1NJIY 3CCUX 3CCLX 1Q81Y 3I56X 3CC7X 3CMAX
chains in the Genus database with same CATH superfamily
3CXCW 1VQ8X 1M1KY 1YJWX 2QA4X 1JJ2W 1Q86Y 1KQSW 1VQNX 2OTLX 3G6EX 1N8RY 1QVGW 1VQLX 1W2BW 1M90Y 3G71X 1YJNX 3CCRX 1K8AY 1VQ6X 3CCJX 3CCQX 3G4SX 1VQ9X 1VQ5X 1VQ7X 3CMEX 3CCEX 1S72X 1YIJX 2QEXX 2OTJX 3OW2W 1VQKX 1KD1Y 3CCSX 1YHQX 1VQ4X 3CC2X 3I55X 1K9MY 3CPWW 3CC4X 1QVFW 3CD6X 1KC8Y 3CCVX 1YI2X 1K73Y 1YJ9X 1VQOX 1Q7YY 3CCMX 1Q82Y 1YITX 1VQPX 1VQMX 1NJIY 3CCUX 3CCLX 1Q81Y 3I56X 3CC7X 3CMAX
chains in the Genus database with same CATH topology
3CXCW 1VQ8X 1M1KY 1YJWX 2QA4X 1JJ2W 1Q86Y 1KQSW 1VQNX 2OTLX 3G6EX 1N8RY 1QVGW 1VQLX 1W2BW 1M90Y 3G71X 1YJNX 3CCRX 1K8AY 1VQ6X 3CCJX 3CCQX 3G4SX 1VQ9X 1VQ5X 1VQ7X 3CMEX 3CCEX 1S72X 1YIJX 2QEXX 2OTJX 3OW2W 1VQKX 1KD1Y 3CCSX 1YHQX 1VQ4X 3CC2X 3I55X 1K9MY 3CPWW 3CC4X 1QVFW 3CD6X 1KC8Y 3CCVX 1YI2X 1K73Y 1YJ9X 1VQOX 1Q7YY 3CCMX 1Q82Y 1YITX 1VQPX 1VQMX 1NJIY 3CCUX 3CCLX 1Q81Y 3I56X 3CC7X 3CMAX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CXC W;  1VQ8 X;  1M1K Y;  1YJW X;  2QA4 X;  1JJ2 W;  1Q86 Y;  1KQS W;  1VQN X;  2OTL X;  3G6E X;  1N8R Y;  1QVG W;  1VQL X;  1W2B W;  1M90 Y;  3G71 X;  1YJN X;  3CCR X;  1K8A Y;  1VQ6 X;  3CCJ X;  3CCQ X;  3G4S X;  1VQ9 X;  1VQ5 X;  1VQ7 X;  3CME X;  3CCE X;  1S72 X;  1YIJ X;  2QEX X;  2OTJ X;  3OW2 W;  1VQK X;  1KD1 Y;  3CCS X;  1YHQ X;  1VQ4 X;  3CC2 X;  3I55 X;  1K9M Y;  3CPW W;  3CC4 X;  1QVF W;  3CD6 X;  1KC8 Y;  3CCV X;  1YI2 X;  1K73 Y;  1YJ9 X;  1VQO X;  1Q7Y Y;  3CCM X;  1Q82 Y;  1YIT X;  1VQP X;  1VQM X;  1NJI Y;  3CCU X;  3CCL X;  1Q81 Y;  3I56 X;  3CC7 X;  3CMA X; 
#chains in the Genus database with same CATH topology
 3CXC W;  1VQ8 X;  1M1K Y;  1YJW X;  2QA4 X;  1JJ2 W;  1Q86 Y;  1KQS W;  1VQN X;  2OTL X;  3G6E X;  1N8R Y;  1QVG W;  1VQL X;  1W2B W;  1M90 Y;  3G71 X;  1YJN X;  3CCR X;  1K8A Y;  1VQ6 X;  3CCJ X;  3CCQ X;  3G4S X;  1VQ9 X;  1VQ5 X;  1VQ7 X;  3CME X;  3CCE X;  1S72 X;  1YIJ X;  2QEX X;  2OTJ X;  3OW2 W;  1VQK X;  1KD1 Y;  3CCS X;  1YHQ X;  1VQ4 X;  3CC2 X;  3I55 X;  1K9M Y;  3CPW W;  3CC4 X;  1QVF W;  3CD6 X;  1KC8 Y;  3CCV X;  1YI2 X;  1K73 Y;  1YJ9 X;  1VQO X;  1Q7Y Y;  3CCM X;  1Q82 Y;  1YIT X;  1VQP X;  1VQM X;  1NJI Y;  3CCU X;  3CCL X;  1Q81 Y;  3I56 X;  3CC7 X;  3CMA X; 
#chains in the Genus database with same CATH homology
 3CXC W;  1VQ8 X;  1M1K Y;  1YJW X;  2QA4 X;  1JJ2 W;  1Q86 Y;  1KQS W;  1VQN X;  2OTL X;  3G6E X;  1N8R Y;  1QVG W;  1VQL X;  1W2B W;  1M90 Y;  3G71 X;  1YJN X;  3CCR X;  1K8A Y;  1VQ6 X;  3CCJ X;  3CCQ X;  3G4S X;  1VQ9 X;  1VQ5 X;  1VQ7 X;  3CME X;  3CCE X;  1S72 X;  1YIJ X;  2QEX X;  2OTJ X;  3OW2 W;  1VQK X;  1KD1 Y;  3CCS X;  1YHQ X;  1VQ4 X;  3CC2 X;  3I55 X;  1K9M Y;  3CPW W;  3CC4 X;  1QVF W;  3CD6 X;  1KC8 Y;  3CCV X;  1YI2 X;  1K73 Y;  1YJ9 X;  1VQO X;  1Q7Y Y;  3CCM X;  1Q82 Y;  1YIT X;  1VQP X;  1VQM X;  1NJI Y;  3CCU X;  3CCL X;  1Q81 Y;  3I56 X;  3CC7 X;  3CMA X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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