3HK8A

Crystal structure of uronate isomerase from bacillus halodurans complexed with zinc and d-arabinohydroxamate
Total Genus 164
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
164
sequence length
409
structure length
409
Chain Sequence
SREVLAEKVKNAVNNQPVTDMHTHLFSPNFGEILLWDIDELLTYHYLVAEVMRWTDVSIEAFWAMSKREQADLIWEELFIKRSPVSEACRGVLTCLQGLGLDPATRDLQVYREYFAKKTSEEQVDTVLQLANVSDVVMTNDPFDDNERISWLEGKQPDSRFHAALRLDPLLNEYEQTKHRLRDWGYKVNDEWNEGSIQEVKRFLTDWIERMDPVYMAVSLPPTFSFPEESNRGRIIRDCLLPVAEKHNIPFAMMIGVKKRVHPALGDAGDFVGKASMDGVEHLLREYPNNKFLVTMLSRENQHELVVLARKFSNLMIFGCWWFMNNPEIINEMTRMRMEMLGTSFIPQHSDARVLEQLIYKWHHSKSIIAEVLIDKYDDILQAGWEVTEEEIKRDVADLFSRNFWRFVG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily.
pubmed doi rcsb
molecule tags Isomerase
source organism Bacillus halodurans c-125
molecule keywords Uronate isomerase
total genus 164
structure length 409
sequence length 409
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-05-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.2020.10 Mainly Alpha Orthogonal Bundle uronate isomerase, domain 2, chain A uronate isomerase, domain 2, chain A 3hk8A02
1J5SA 2Q01A 2QEEA 3HKAA 4I6VA 3HK9A 3IACA 2Q6EA 2PNKA 3HK8A 2Q08A 3HK7A 3HK5A
chains in the Genus database with same CATH superfamily
1J5SA 2Q01A 2QEEA 3HKAA 4I6VA 3HK9A 3IACA 2Q6EA 2PNKA 3HK8A 2Q08A 3HK7A 3HK5A
chains in the Genus database with same CATH topology
1J5SA 2Q01A 2QEEA 3HKAA 4I6VA 3HK9A 3IACA 2Q6EA 2PNKA 3HK8A 2Q08A 3HK7A 3HK5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J5S A;  2Q01 A;  2QEE A;  3HKA A;  4I6V A;  3HK9 A;  3IAC A;  2Q6E A;  2PNK A;  3HK8 A;  2Q08 A;  3HK7 A;  3HK5 A; 
#chains in the Genus database with same CATH topology
 1J5S A;  2Q01 A;  2QEE A;  3HKA A;  4I6V A;  3HK9 A;  3IAC A;  2Q6E A;  2PNK A;  3HK8 A;  2Q08 A;  3HK7 A;  3HK5 A; 
#chains in the Genus database with same CATH homology
 1J5S A;  2Q01 A;  2QEE A;  3HKA A;  4I6V A;  3HK9 A;  3IAC A;  2Q6E A;  2PNK A;  3HK8 A;  2Q08 A;  3HK7 A;  3HK5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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